Journal Club - Archiv - 2008

2007, 2008, 2009
Laboratory of Č. Vlček organizes Journal Clubs on Mondays at 9:00 in the seminar room on the 2nd floor.

January 7 - Presentation by Jana Šáchová
January 14 - Presentation by Petr Vojta
 
Laboratories of L. Krásný (Inst. Microbiol.) together with laboratories of D. Staněk (IMG) and J. Malinsky Lab (Inst. Exp. Med.) organize Journal Clubs on Mondays at 15:00 p in the Blue Lecture Room (LB building - 2nd floor). More information and the selected papers to be discussed during the sessions are available below.  (webside)



Laboratories of Z. Kozmik organize joint Journal Clubs on Tuesdays at 9:00 in the seminar room on the 2nd floor.



Laboratory of Pa. Dráber organizes Journal Club on Wednesdays at 10:30 a.m. in the Seminar Room (3rd floor). More information and the papers to be discussed during the sessions are available below.

January 2 - A.V. Nikonov, H. P. Hauri, B. Lauring, G. Kreibich: Climp-63-mediated binding of microtubules to the ER affects the lateral mobility of translocon complexes. J Cell Sci 120: 2248-2258, 2007.  PubMed
January 30 - J.T. Smyth, W.I. DeHaven, G.S. Bird, J. W. Putney: Role of the microtubule cytoskeleton in the function of the store-operated Ca2+ channel activator STIM1, J Cell Sci.120, 3762-71, 2007. PubMed
February 20 - L. J. Terry, E. B. Shows, S. R. Wente: Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport. Science 318: 1412-1416, 2007.  PubMed
March 12 - B. Manavathi, F. Acconcia, S. K. Rayala, R. Kumar. An inherent role of microtubule network in the action of nuclear receptor.Proc Natl Acad Sci USA 103, 15981-6, 2006. Pubmed
April 2 - D Stanislav Vinopal - Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW Jr, Hoogenraad CC, Akhmanova A. STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol. 18(3): 177-82, 2008. PubMed
April 16 - Presentation by Barbora Horejsi - Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW Jr, Hoogenraad CC, Akhmanova A. STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol. 18(3): 177-82, 2008. PubMed
April 30 - N. Izumi, K. Fumoto, S. Izumi, A. Kikuchi: GSK-3beta regulates proper mitotic spindle formation in cooperation with a component of the gamma -tubulin ring complex, GCP5.J Biol Chem. 2008 Mar 3; [Epub ahead of print]
July 9 - Smyth JT, Dehaven WI, Bird GS, Putney JW Jr.: Ca2+-store-dependent and -independent reversal of Stim1 localization and function. J Cell Sci. 2008 Mar 15;121(Pt 6):762-72. Epub 2008 Feb 19. PubMed
August 20 - Barrett SL, Albertini DF Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte. Biol Reprod. 2007 Jun;76(6):949-57. Epub 2007 Feb 7. PubMed
November 26 - S.V. Bratman, F. Chang - Mechanisms for maintaining microtubule bundles. Trends Cell Biol. 566, 2008 [Epub ahead of print] PubMed

Laboratory of M. Lipoldová organizes Journal Club on Wednesdays at 13:00 a.m. in the Seminar Room (1st floor). More information and the papers to be discussed during the next session are available below.

January 16 - Presentation by Vanda Valentová - Levine B, Deretic V.: Unveiling the roles of autophagy in innate and adaptive immunity. Nat. Rev. Immunol. 7: 767-777, 2007. Detail
Laboratory of J. Forejt and P. Svoboda organizes Journal Club on Thursdays at 8:30 a.m. in the Seminar Room (1st floor). More information and the papers to be discussed during the next session are available below.



Laboratories of V. Hořejší and D. Filipp organize joint Journal Clubs on Thursdays at 12:30 in the seminar room on the 2nd floor. More information and the papers to be discussed during the sessions are available below.

January 10 - Presentation by Ondřej Ballek - Filby A, Seddon B, Kleczkowska J, Salmond R, Tomlinson P, Smida M, Lindquist JA, Schraven B, Zamoyska R.:  Fyn Regulates the Duration of TCR Engagement Needed for Commitment to Effector Function  J Immunol 179: 4635-4644 , 2007. Detail
January 24 - Presentation by Vaclav Hořejší -
1)  Posevitz-Fejfár A, Smída M, Kliche S, Hartig R, Schraven B, Lindquist JA.
A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration.
Eur J Immunol. 2008 Jan;38(1):250-9. Detail
2) Tauzin S, Ding H, Khatib K, Ahmad I, Burdevet D, van Echten-Deckert G, Lindquist JA, Schraven B, Ud-Din N, Borisch B, Hoessli DC.
Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts. Blood. 2007 Dec 10; [Epub ahead of print] Detail
January 31 - Presentation by Karel Drbal - Yoshihisa Kaizuka, Adam D. Douglass, Rajat Varma, Michael L. Dustin, and Ronald D. Vale: Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. PNAS 104(51), 20296-20301, 2007.
February 7 - Presented by Pavel Otáhal - Chichili GR, Rodgers W. Clustering of membrane raft proteins by the actin cytoskeleton. J Biol Chem. 282(50): 36682-91, 2007.  Detail
February 14 - Presentation by Václav Hořejší - Recent important immunological papers of general interest - a brief overview.
February 21 - Presentation by Ondřej Štěpánek - Peer D, Park EJ, Morishita Y, Carman CV, Shimaoka M.: Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science. 2008 Feb 1;319(5863):627-30.  Detail
February 28 - Presentation by Matouš Hrdinka -
Matza D, Badou A, Kobayashi KS, Goldsmith-Pestana K, Masuda Y, Komuro A, McMahon-Pratt D, Marchesi VT, Flavell RA. A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation. Immunity. 2008 Jan;28(1):64-74. Detail
Radermacher AN, Crabtree GR. Monster protein controls calcium entry and fights infection.
Immunity. 2008 Jan;28(1):13-4. Detail
March 6 - Presentation by Peter Dráber - Depoil D, Fleire S, Treanor BL, Weber M, Harwood NE, Marchbank KL, Tybulewicz VL, Batista FD.  CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand.  Nat Immunol. 2008 Jan;9(1):63-72. Epub 2007 Dec 2. Detail
March 13 - Presentation by Lukáš Chmátal - Chu CL, Yu YL, Shen KY, Lowell CA, Lanier LL, Hamerman JA. Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma.Eur J Immunol. 2008 Jan;38(1):166-73.  Detail
March 20 - Presentation by Ivana Vonková - Martha S. Jordan, Jennifer E. Smith, Jeremy C. Burns, Jessica-Elise T. Austin, Kim E. Nichols, Anna C.  Aschenbrenner and Gary A. Koretzky: Complementation In Trans of Altered Thymocyte Development in Mice Expressing Mutant Forms of the Adaptor Molecule SLP76.Immunity 28, 359–369, 2008.  Detail
March 27 - Presentation by Tereza Havlová:
Rebeaud F, Hailfinger S, Posevitz-Fejfar A, Tapernoux M, Moser R, Rueda D, Gaide O, Guzzardi M, Iancu EM, Rufer N, Fasel N, Thome M. The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat Immunol. 9(3): 272-81, 2008.  Detail
- McAllister-Lucas LM, Lucas PC. Finally, MALT1 is a protease! Nat Immunol. 9(3):231-3, 2008. Detail
April 10 - Presentation by Dominik Filipp Mark E. Kleinman et al: Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
Nature,doi:10.1038/nature06765; Published online 26 March 2008 Detail
April 17 - Presentation by Tomáš Brdička -
1) Oh-Hora M, Yamashita M, Hogan PG, Sharma S, Lamperti E, Chung W, Prakriya M, Feske S, Rao A. Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nat Immunol. 2008 Apr;9(4):432-43. Detail
2) Baba Y, Nishida K, Fujii Y, Hirano T, Hikida M, Kurosaki T. Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses. Nat Immunol. 2008 Jan;9(1):81-8. Detail
May 15 - Presentation by Ondřej Ballek - Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, Xue Y, Mellman I, Banchereau J, Connolly JE.  Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nat Immunol. 2008 May;9(5):551-7. Detail
May 29 - Presentation by Aleš Neuwirth - Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP. Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.  Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):63 . Detail
August 20 Presentation by Pavel Otáhal - Holst J, et al:  Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures  effective negative selection and prevents autoimmunity. Nat Immunol. 2008 Jun;9(6):658-66.  Comment in: Nat Immunol. 2008 Jun;9(6):583-4. PubMed
October 23 - Presentation by Matouš Hrdinka - Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression.Cell. 2008 Jul 11;134(1):62-73.  PubMed
October 30 Presentation by Peter Dráber - Yokosuka T, Kobayashi W, Sakata-Sogawa K, Takamatsu M, Hashimoto-Tane A, Dustin ML, Tokunaga M, Saito T. Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C theta Translocation.
Immunity 29, 589–601, October 17, 2008. PubMed
November 6 - Presentation by Ondřej Štěpánek - 
  • Oberdoerffer S, Moita LF, Neems D, Freitas RP, Hacohen N, Rao A. Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Science. 2008 Aug 1;321(5889):686-91. PubMed
  • Topp JD, Jackson J, Melton AA, Lynch KW. A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4. RNA. 2008 Oct;14(10):2038-49. PubMed
  • Commentary: Holmes N. A splicing switch for T cells. Science. 2008 Aug 1;321(5889):646-7. PubMed
November 20 - Presentation by Ivana Vonková - Haase H, Ober-Blöbaum JL, Engelhardt G, Hebel S, Heit A, Heine H, Rink L. Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes. J Immunol. 2008 Nov 1;181(9):6491-502. PubMed
December 11 - presentation by Václav Hořejší - Veracini L, Simon V, Richard V, Schraven B, Horejsi V, Roche S, Benistant C.
The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1. J Cell Biol. 2008 Aug 11;182(3):603-14.  PubMed
 
Laboratories of M. Reiniš and V. Holáň organizes Journal Club on Thursdays at 3:00 p.m. in the Seminar Room (2nd floor). More information and the papers to be discussed during the next session are available below.

February 7 - Butte at al.: Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses. Immunity 2007. PubMed
February 21 - Elias et al.: Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway, Blood 2008. PubMed
March 27 - Prevosto C, Zancolli M, Canevali P, Zocchi  MR, Poggi A. Generation of CD4+ or CD8+ regulatory cells upon mesenchymal stem cell-lymphocyte interaction. Haematologica 92: 881-8, 2007. PubMed
 
Laboratories of P. Bartůněk, M. Dvořák and J. Hejnar organizes Journal Club on every 2nd Thursdays at 5:00 p.m. in the Seminar Room (3rd floor). More information and the papers to be discussed during the next session are available below.

January 10 - Presentation by Jiří Plachý - Feng Yang, Rena R. Xian, Yingying Li, Tatjana S. Polony, and Karen L. Beemon: Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas. PNAS 104: 18952–18957, 2007.  Detail
January 24 - Presentation by Jan Kosla
Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ. Irf6 is a key determinant of
he keratinocyte proliferation-differentiation switch. Nat Genet. 2006 Nov; 38(11):1329-34. Epub 2006 Oct 15.
PubMed
February 7 - Presented by Jana Blažková - Tyagi M, Karn J.: CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency.  EMBO J. 26(24): 4985-95, 2007. PubMed
March 6 - Presentation by Magda Matoušková Mangeney M, Renard M, Schlecht-Louf G, Bouallaga I, Heidmann O, Letzelter C, Richaud A, Ducos B, Heidmann T. Placental syncytins: Genetic disjunction betweenthe fusogenic and immunosuppressive activity of retroviral envelope proteins. PNAS 104: 20534–20539, 2007. PubMed
March 20 - Sima N, Wang W, Kong D, Deng D, Xu Q, Zhou J, Xu G, Meng L, Lu Y, Wang S, Ma D. RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53. Apoptosis 13(2): 273-81, 2008. PubMed
April 3 - Presentation by Filip Šenigl - A Poleshko, I Palagin, R Zhang, P Boimel, C Castagna, P D Adams, A M Skalka, R A Katz. Identification of Cellular Proteins That Maintain Retroviral EpigeneticSilencing: Evidence for an Antiviral Response. Journal of Virology 82: 2313–2323, 2008. PubMed
May 15 -  Burnside J, Ouyang M, Anderson A, Bernberg E, Lu C, Meyers BC, Green PJ, Markis M, Isaacs GK, Huang E, Morgan RW. Deep Sequencing of Chicken microRNAs. BMC Genomics. 2008 Apr 22;9(1):185 [Epub ahead of print] PMID: 18430245 [PubMed - as supplied by publisher] PubMed  
October 30 Presentation by Kateřina Trejbalová -  Suzuki et al. Closed Chromatin Architecture Is Induced by an RNA Duplex Targeting the HIV-1 Promoter Region. J. Biol. Chem. 283, 23353-23363, 2008.  PubMed
November 20 - Presentationby Magda Matoušková - Esnault C, Priet S, Ribet D, Vernochet C, Bruls T, Lavialle C, Weissenbach J, Heidmann T. A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2. Proc Natl Acad Sci U S A 105(45):17532-7, 2008. PubMed
 
Laboratory of Pe. Dráber organizes Journal Club on Fridays at 8:15 a.m. in the Seminar Room (2nd floor). More information and the papers to be discussed during the sessions are available below.

January 18 - Presentation by Martin Machyna
Laboratory of P. Hozák organizes Journal Club on Fridays at 10:00 a.m. in the Seminar Room (1st floor). More information and the papers to be discussed during the sessions are available below.

   
Laboratory of R. Sedláček organizes Journal Club on Friday at 12:00 a.m. in the Seminar Room (3nd floor). More information and the papers to be discussed during the next session are available below.

December 12 - Presentation by Alexandra Mayer - Popov Y, Patsenker E, Stickel F, Zaks J, Bhaskar KR, Niedobitek G,  Kolb A, Friess H, Schuppan D: Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies, J Hepatol 48: 453–464, 2008. PubMed