Research topics
Haematopoietic and neuronal cell development, differentiation, cell fate, leukaemia, nuclear hormone receptors, growth factor receptors, cell cycle regulators, chemical genetics
Current Grant Support
Ministry of Education, Youth and Sports of the Czech Republic, Center for Chemical Genetics (grant No. LC06077)
Ministry of Industry and Trade (grant No. FT-TA5/136)
European Comission (FP6 Integrated Project CRESCENDO Project No. 018652)
Academy of Sciences of the Czech Republic (grant No. IAA500520705)
Grant Agency of the Czech Republic (grants No. GA310/08/0878, GA204/09/1905)
Most important recent papers
(2003-present; names of the lab members underlined)Bartunek, P., Kralova, J., Blendinger, G., Dvorak, M., Zenke, M.: GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter. Oncogene 22: 1927-1935, 2003. (PubMed)
Karafiat, V., Dvorakova, M., Krejci, E., Kralova, J., Pajer, P., Snajdr, P., Mandikova, S., Bartunek, P., Grim, M., Dvorak, M.: Transcription factor c-Myb is involved in the regulation of the epithelial-mesenchymal transition in the avian neural crest. Cell Mol. Life Sci. 62: 2516-2525, 2005. (PubMed)
Kaspar, P., Pajer, P., Sedlak, D., Tamaoki, T., Dvorak, M.: c-Myb inhibits myogenic differentiation through repression of MyoD. Exp. Cell Res. 309: 419-428, 2005. (PubMed)
Bartunek, P., Karafiat, V., Bartunkova, J., Pajer, P., Dvorakova, M., Kralova, J. , Zenke, M., Dvorak M.: The impact of chicken thrombopoietin and its receptor c-Mpl on hematopoietic cell development. Exp. Hematol. 36: 495-505, 2008. (PubMed)
Zikova, M., Corlett, A., Bendova, A., Pajer, P., Bartunek, P.: DISP3, a sterol-sensing domain containing protein: a new molecular link between thyroid hormone action and cholesterol metabolism. Mol. Endocrinol. 23: xxx-xxx, 2009. (PubMed)