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List of scientific communications awarded the Prize of AS CR



List of ten papers dealing with the significance of membrane microdomains and their novel protein components in immunoreceptor signalling:
1) Brdička T, Pavlištová D, Leo A, Bruyns E, Kořínek V, Angelisová P, Scherer J, Shevchenko A, Hilgert I, Černý J, Drbal K, Kuramitsu Y, Kornacker B, Hořejší V, Schraven B: Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase Csk and is involved in regulation of T cell activation. J. Exp. Med. 191: 1591-1604, 2000. (PubMed)

2) Brdičková N, Brdička T, Anděra L, Špička J, Angelisová P, Milgram SL, Hořejší V: Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton. FEBS Lett. 507:133-6, 2001. (PubMed)

3) Hořejší V: Membrane rafts in immunoreceptor signaling: new doubts, new proofs? Trends Immunol. 23: 562-564, 2002. (PubMed)

4) Brdička T, Imrich M, Angelisová P, Brdičková N, Horváth O, Špička J, Hilgert I, Lusková P, Dráber P, Novák P, Engels N, Wienands J, Simeoni L,  Osterreicher J, Aguado E, Malissen M, Schraven B, Hořejší V: NTAL (Non-T cell activation linker): a transmembrane adaptor protein involved in immunoreceptor signaling. J. Exp. Med. 196: 1617-1626, 2002. (PubMed)

5) Kropshofer H, Spindeldreher S, Rohn TA, Platania N, Grygar C, Daniel N,Wolpl A, Langen H, Hořejší V, Vogt AB: Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes. Nature Immunol. 3: 61-8, 2002. (PubMed)

6) Leo A, Wienands J, Baier G, Hořejší V, Schraven B: Adapters in lymphocyte signaling. J. Clin. Invest. 109:301-9, 2002. (PubMed)

7) Baumgartner M, Angelisová P, Setterblad N, Mooney N, Werling D, Hořejší V, Langsley G: Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes. Blood. 101:1874-81, 2003. (PubMed)

8) Hořejší V: The roles of membrane microdomains (rafts) in T cell activation. Immunol. Rev. 191: 148-64, 2003. (PubMed)

9) Brdičková N, Brdička T, Angelisová P, Horváth O, Špička J, Hilgert I, Pačes J, Simeoni L, Kliche S, Merten C, Schraven B, Hořejší V: LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling. J. Exp. Med. 198:1453-62, 2003. (PubMed)

10) Hořejší V, Zhang W, Schraven B: Transmembrane adaptor proteins: organizers of immunoreceptor signalling. Nature Rev. Immunol. 4: 603-16, 2004. (PubMed)

Team of authors of the scientific communication:
Head:   Václav Hořejší
Members:   Ladislav Anděra, Pavla Angelisová,  Tomáš Brdička, Naděžda Brdičková, Jan Černý, Karel Drbal, Ivan Hilgert, Ondrej Horváth, Vladimír Kořínek, Jiří Špička


 



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