1. Cellular and molecular mechanisms of pain transmission at spinal cord level.

2. Mechanisms of spinothalamic tract neurons sensitization in relation to hyperalgesia and allodynia.

3. The role of dorsal column pathway and postsynaptic dorsal column neurons in visceral pain.

4. Effect of exo- and endogenous factors on muscle differentiation, mRNA and protein isoforms of contractile and Ca 2+ transporting proteins.

5. Morphological substrate of muscle pain, properties and distribution of nociceptive primary afferent fibres in fast and slow skeletal muscles.

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