03.12.2008 - Journal article in prestige journal Nature Genetics

The article in prestige journal Nature Genetics on molecular-genetic basis of severe inherited mitochondrial disease – neonatal encephalo-cardiomyopathy.

Studies on pathogenic mechanism of novel mitochondrial disorder resulted in identification of disease causing mutation in the TMEM70 gene which encodes a new type of ancillary factor essential for biogenesis of ATP synthase that is unique for higher eukaryotes. Results of collaborative studies performed at the Institute of Physiology ASCR, Institute of Inherited Metabolic Disorders and Pediatric Department of the 1st Medical Faculty CU were published in Nature Genetics.

Cízková A, Stránecký V, Mayr JA, Tesarová M, Havlícková V, Paul J, Ivánek R, Kuss AW, Hansíková H, Kaplanová V, Vrbacký M, Hartmannová H, Nosková L, Honzík T, Drahota Z, Magner M, Hejzlarová K, Sperl W, Zeman J, Houstek J, Kmoch S.: TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy. Nat. Genet. 2008, 40, 1288-1290 IF= 25.55

Author: houstek@biomed.cas.cz

22.3.2010 - 25th International Symposium on MicroScale Bioseparations Prague, March 21-25, 2010
Welcome to the 25th International Symposium on MicroScale Bioseparations Prague, March 21-25, 2010

11.6.2009 - Laser microdissection system Leica LMD600
Laser microdissection system Leica LMD600 was installed in the Institute of Physiology.

03.6.2009 - FLIM seminar
June 3, 2009: Seminar on Fluorescence Lifetime Imaging Techniques at the Institute of Physiology

28.5.2009 -  INVITATION
8th EUROPEAN FORUM FOR SCIENCE AND TECHNOLOGY

21.5.2009 - Special Award for Dr. Pavel Flachs
Dr. P. Flachs was awarded with Otto Wichterle Premium

18.2.2009 - The Honorary Medal of J. E. Purkynje for Dr. Jaroslav Kunes
The Honorary Medal of J. E. Purkynje for Dr. Jaroslav Kunes

03.12.2008 - Review articles in prestige journal Nature Genetics
Identification of distribution and functional impact of DNA copy number variation in the rat

03.12.2008 - Review articles in prestige journal Nature Genetics
Identification of renal Cd36 as a genetic determinant of blood pressure and risk for hypertension

27.8.2008 - IMPORTANT INFORMATION FOR FOREIGNERS FROM THIRD COUNTRIES
Nowadays, the research workers can apply for the long-term residence permission (not anymore for the visa granted for a stay longer than 90 days) for the purpose of scientific research.