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Senior Scientist, Project Leader
Chemistry of Functional Molecules Research Group
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic
Phone: (+420) 220 183 382 (465)
Fax: (+420) 220 183 133
E-mail: petrholy@uochb.cas.cz
http://www.cfm.uochb.cz
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Petr Holý - Background
Personal data
Born in Prague, Czech Republic, in 1949
Professional preparation
| 1979 |
Ph.D. (CSc.) in Organic Chemistry, under supervision of Prof. M. Janda, Institute of Chemical Technology, Prague |
| 1973 |
M.Sc. (Ing.) in Organic Chemistry, under supervision of Prof. M. Janda, Institute of Chemical Technology, Prague |
Experience
| 1989-1990 |
Postdoctoral fellow with Prof. W. Simon, ETH Zürich, Switzerland |
Appointments
| Currently |
Senior scientist and a project leader in the Chemistry of Functional Molecules Research Group,
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague |
| 1994-2006 |
Head of the Supramolecular group at Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague |
| Since 1986 |
He has joined the Department of Organic Chemistry, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague
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| 1979-1985 |
Research worker with Prof. Z. Vodrážka at the Biochemical Department of the Institute of Hematology and Blood Transfusion, Prague
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Awards and organizations
| Since 2002 |
Member of the Editorial Board of the Czech national chemical journal "Chemické listy" |
Research interest
Synthetic organic chemistry, supramolecular chemistry, crystal engineering.
Petr Holý - Selected papers
Rybáčková, M.; Bělohradský, M.; Holý, P.; Pohl, R.; Dekoj, V.; Závada, J.
Synthesis 2007, 1554-1558.
Synthesis of Highly Symmetrical Triptycene Tetra- and Hexacarboxylates.
Rybáček, J.; Rybáčková, M.; Høj, M.; Bělohradský, M.; Holý, P.; Kilså, K.; Nielsen M.B.
Tetrahedron 2007, 63, 8840-8854.
Tetrathiafulvalene-Functionalized Triptycenes: Synthetic Protocols and
Elucidation of Intramolecular Coulomb Repulsions in the Oxidized Species.
Holý, P.; Havlík, M.; Tichý, M.; Závada, J.; Císařová, I.
Collect. Czech. Chem. Commun. 2006, 71, 138-154.
Synthesis ans self-assembly of 9,9´-spirobifluorene-2,2´,7,7´-tetracarboxylic
acid and its tetraamide. Non-catenated formation of achiral grid layers with large chiral pores.
Holý, P.; Kováč, M.; Tichý, M.; Závada, J.; Buděšínský, M.; Císařová, I.
Tetrahedron: Asymmetry 2005, 16, 2031-2038.
Interpenetrating chiral 2D grid nets: hetero- versus homochiral 3D polycatenation in the crystal self-assembly of (RS)- and
(R)-1,1´-binaphthalene-2,2´,6,6´-tetracarboxylic acids.
Holý, P.; Sehnal P., Tichý, M.; Závada, J.; Císařová, I.
Tetrahedron: Asymmetry 2004, 15, 3805-3810.
Crystal structure of 1,1´-biphenyl-2,2´,3,3´-tetracarboxylic and 1,1´-biphenyl-2,2´,3,3´,5,5´,6,6´-octacarboxylic acids:
solid state chiralization and dissociation.
Bělohradský, M.; Buděšínský, M.; Císařová, I.; Dekoj, V.; Holý, P.; Závada, J.
Tetrahedron 2003, 59, 7751-7760.
Macrocyclic cis- and trans- Bis(α-amino Acids)
and their Intraannular Cu(II) Complexes. Conformational in-out Dichotomy and Crystal Packing.
Holý, P.; Sehnal P., Tichý, M.; Závada, J.; Císařová, I.
Tetrahedron: Asymmetry 2003, 14, 245-253.
Self-assembly of chiral hydrogen-bonded grid layers from terephthalic Siamese twins.
Bělohradský, M.; Císařová, I.; Holý, P.; Pastor, J.; Závada, J.
Tetrahedron 2002, 58, 8811-8823.
α-Amino Acids and Dioxopiperazines Crowned at the α-Carbons with
Polyether Macrorings. Synthesis, Complexation and Self-Assembling Properties.
Sehnal, P.; Holý, P.; Tichý, M.; Závada, J.; Císařová, I.
Collect. Czech. Chem. Commun. 2002, 67, 1236-1246.
Synthesis and self-assembling properties of the free base and the
1:1 silver(I)triflate complex.
Holý, P.; Závada, J.; Císařová, I.; Podlaha, J.
Tetrahedron: Asymmetry 2001, 12, 3035-3045.
Self-assembly of enantiopure and racemic 2,2´,6,6´-tetrasubstituted biaryl
tectons into hydrogen bonded chiral squares and infinite chiral square layers.
Tichý, M.; Holý, P.; Závada, J.; Císařová, I.; Podlaha, J.
Tetrahedron: Asymmetry 2001, 12, 2295-2300.
Helix-forming self-assembly of enantiopure 2,2´-dimethylbiphenyl-6,6´-dipropiolic
acid and amide organized by hydrogen bonds.
Holý, P.; Závada, J.; Zezula, J.; Císařová, I.; Podlaha, J.
Collect. Czech. Chem. Commun. 2001, 66, 820-832.
Formation of infinite grids with chiral square compartments by self-assembly
of achiral 1,1´-biphenyl-2,2´,6,6´-tetracarboxylic acids. Effect of 4,4´-substitution on the grid stacking.
Holý, P.; Podlaha, J.; Císařová, I.; Závada, J.
Collect. Czech. Chem. Commun. 2001, 66, 947-958.
Self-assembly of 1,1´-biphenyl-2,2´,6,6´-tetracarboxamides. Effect of
substitution at the amidic nitrogen.
Holý, P.; Závada, J.;, Podlaha, J.; Císařová, I.
Angew. Chem. Int. Ed., 1999, 38, 381-383.
Self-assembly of 1,1´-biphenyl-2,2´,6,6´-tetracarboxylic acid: Formation of an
achiral grid with chiral compartments.
Tichý, M.; Ridvan, L.; Holý, P.; Závada, J.; Císařová, I.; Podlaha, J.
Tetrahedron: Asymmetry 1998, 9, 227-234.
Axially chiral dilactams. Synthesis, racemization barriers and crystal structures.
Holý, P.; Havránek, M.; Pánková, M.; Ridvan, L.; Závada, J.
Tetrahedron 1997, 53, 8195-8210.
Solvent and leaving group effects on the mono- vs. dialkylation of alkali salts
of diethyl malonate with 1,2-bis-, 1,2,4,5-tetrakis- and 1,2,3,4,5,6-hexakis(halomethyl)benzenes. A new insight into selectivity control
of malonester synthesis.
Bělohradský, M.; Buděšínský, M.; Günterová, J.; Hodačová, J.; Holý, P.; Závada, J.; Císařová, J.; Podlaha, J.
Tetrahedron 1996, 52, 11013-11024
C-C coupling reaction of 1,5-dibromo-2,6-dihydroxynaphthalene with alkali 2-naphthoxide.
Opposite effects of counterion coordination and hydrogen bonding on stereoselectivity in the formation of cis- and
trans-1,1':5',1''-ternaphthyls.
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