Ameboid Invasivity of Tumour Cells

Brábek J., Rösel D.

Invasivity of malignant tumour cells is a critical stage in the onset of metastases. At present two main types of invasion process in cells are known: mesenchymal invasivity based on degradation of intercellular substances and a newly described ameboid invasivity characterized by enhanced activity of the enzyme Rho-kinase. Various opinions on the mechanism of ameboid invasivity are discussed.

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