Group of Biochemistry of Antimetabolites

Ivan Votruba, PhD., Head

DEPARTMENT OF NUCLEIC ACID CHEMISTRY
Institute of Organic Chemistry and Biochemistry, Prague, Czech Republic

INTRODUCTION
PROJECTS
STAFF
SUPPORT
PAPERS
COLLABORATION
Research Projects:
  1. Interaction of the phosphates of phosphonomethoxyalkyl purines with NDP kinase
     
  2. Interaction of the diphosphates of phosphonomethoxyalkyl purines with telomerase
     
  3. N6-Substituted derivatives of PMEDAP as pro-drugs of PMEG
     
  4. Inhibitors of thymidine phosphorylase - potential anti-angiogenic agents
     
  5. The influence of methylation cofactors (SAH, SAM) levels on DNA methylation