In this work, we will present the varieties of effects of the tropospheric-generated acoustic-gravity-waves (AGWs) in the generation and suppression of plasma bubbles. Using three-dimensional coupled simulation model of AGW-plasma bubble, it will be shown that AGW is a possible candidate for the seeding of collisional-interchange instability (CII). It provides the wind perpendicular to the Earthś magnetic field that has strong vertical shear. Such wind and associated shear may efficiently excite the CII and plasma bubble. On the other hand, AGW also provides wind parallel to Earthś magnetic field that may act to suppress the CII and plasma bubble. The competing role of wind components associated with AGWs to excite and suppress the plasma bubble will be examined in this work.