Fyziologický ústav

Oddělení: Membránové receptory

Seznam publikací v časopisech s impaktem.

Autoři z oddělení jsou označeni červeně.
Autoři FGU podtržením jména.
Aktualizováno 11.2.2010

2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993

2010

1.
Petráčková D. - Šemberová L. - Halada P. - Svoboda P. - Svobodová J.
Stress Proteins in the Cytoplasmic Membrane Fraction of Bacillus subtilis.
Folia Microbiologica, 55(5), 427-434, 2010
IF = 0.978(09)

2.
Drastichová Z. - Bouřová L. - Hejnová L. - Jedelský P. - Svoboda P. - Novotný J.
Protein alterations induced by long-term agonist treatment of HEK293 cells expressing thyrotropin-releasing hormone receptor and G11alpha protein.
Journal of Cellular Biochemistry, 109(1), 255-264, 2010
IF = 2.935(09)

3.
Řežábková L. - Bouřa E. - Herman P. - Večeř J. - Bouřová L. - Šulc M. - Svoboda P. - Obšilová V. - Obšil T.
14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
Journal of Structural Biology, 170(3), 451-461, 2010
IF = 3.673(09)

4.
Bouřová L. - Vošahlíková M. - Kagan D. - Dlouhá K. - Novotný J. - Svoboda P.
Long-term adaptation to high doses of morphine causes desensitization of micro-OR- and delta-OR-stimulated G-protein response in forebrain cortex but does not decrease the amount of G-protein alpha subunits.
Medical Science Monitor, 16(8), BR260-BR270, 2010
IF = 1.543(09)

5.
Burdíková Z. - Čapek M. - Ostašov P. - Machač J. - Pelc R. - Mitchell E.A.D. - Kubínová L.
Testate Amoebae Examined by Confocal and Two-Photon Microscopy: Implications for Taxonomy and Ecophysiology.
Microscopy and Microanalysis, 16(6), 735-746, 2010
IF = 3.035(09)

6.
Folbergrová J. - Ješina P. - Haugvicová R. - Lisý V. - Houštěk J.
Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid.
Neurochemistry International, 56(3), 394-403, 2010
IF = 3.541(09)

2009

1.
Sýkora J. - Bouřová L. - Hof M. - Svoboda P.
The effect of detergents on trimeric G-protein activity in isolated plasma membranes from rat brain cortex: Correlation with studies of DPH and Laurdan fluorescence.
Biochimica Et Biophysica Acta-Biomembranes, 1788(2), 324-332, 2009
IF = 3.998(09)

2.
Bouřová L. - Stöhr J. - Lisý V. - Rudajev V. - Novotný J. - Svoboda P.
G-protein activity in Percoll-purified plasma membranes, bulk plasma membranes, and low-density plasma membranes isolated from rat cerebral cortex.
Medical Science Monitor, 15(4), BR111-BR122, 2009
IF = 1.543(09)

2008

1.
Ostašov P. - Krůšek J. - Durchánková D. - Svoboda P. - Novotný J.
Ca2plus responses to thyrotropin-releasing hormone and angiotensin II: the role of plasma membrane integrity and effect of G11 protein overexpression on homologous and heterologous desensitization.
Cell Biochemistry and Function, 26(2), 264-274, 2008
IF = 1.333(08)

2.
Drastichová Z. - Bouřová L. - Lisý V. - Hejnová L. - Rudajev V. - Stöhr J. - Durchánková D. - Ostašov P. - Teisinger J. - Soukup T. - Novotný J. - Svoboda P.
Subcellular redistribution of trimeric G-proteins – potential mechanism of desensitization of hormone response: internalisation, solubilization, down-regulation.
Physiological Research, 57, S1-S10, 2008
IF = 1.653(08)

3.
Durchánková D. - Novotný J. - Svoboda P.
The time-course of agonist-induced solubilization of trimeric Gq?/G11? proteins resolved by two-dimensional electrophoresis.
Physiological Research, 57(2), 195-203, 2008
IF = 1.653(08)

2007

1.
Folbergrová J. - Ješina P. - Drahota Z. - Lisý V. - Haugvicová R. - Vojtíšková A. - Houštěk J.
Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizures.
Experimental Neurology, 204(2), 597-609, 2007
IF = 3.982(07)

2.
Ostašov P. - Bouřová L. - Hejnová L. - Novotný J. - Svoboda P.
Disruption of the Plasma Membrane Integrity by Cholesterol Depletion Impairs Effectiveness of TRH Receptor-Mediated Signal Transduction via Gq/G11 Proteins.
Journal of Receptors and Signal Transduction, 27, 335-352, 2007
IF = 1.815(07)

2006

1.
Novotný J. - Durchánková D. - Ward R. J. - Carrillo J. J. - Svoboda P. - Milligan G.
Functional interactions between the alpha(1b)-adrenoceptor and Galpha(11) are compromised by de-palmitoylation of the G protein but not of the receptor.
Cellular Signalling, 18(8), 1244-1251, 2006
IF = 4.887(06)

2005

1.
Matoušek P. - Durchánková D. - Švandová I. - Novotný J. - Svoboda P.
Agonist-induced tyrosine phosphorylation of Gq/G11 alpha requires the intact structure of membrane domains.
Biochemical and Biophysical Research Communications, 328(2), 526-532, 2005
IF = 3(05)

2.
Mazna P. - Berka K. - Jelínková I. - Balík A. - Svoboda P. - Obšilová V. - Obšil T. - Teisinger J.
Ligand binding to the human MT2 melatonin receptor: The role of residues in transmembrane domains 3, 6, and 7.
Biochemical and Biophysical Research Communications, 332(3), 726-734, 2005
IF = 3(05)

3.
Stöhr J. - Novotný J. - Svoboda P.
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding.
Canadian Journal of Physiology and Pharmacology, 83(7), 573-581, 2005
IF = 1.522(05)

4.
Matoušek P. - Novotný J. - Rudajev V. - Svoboda P.
Prolonged agonist stimulation does not alter the protein composition of membrane domains in spite of dramatic changes induced in a specific signaling cascade.
Cell Biochemistry and Biophysics, 42(1), 21-40, 2005
IF = 2.138(05)

5.
Rudajev V. - Novotný J. - Hejnová L. - Milligan G. - Svoboda P.
Dominant portion of thyrotropin-releasing hormone receptor is excluded from lipid domains. Detergent-resistant and detergent-sensitive pools of TRH receptor and Gq alpha/G11 alpha protein.
Journal of Biochemistry, 138(2), 111-125, 2005
IF = 1.827(05)

6.
Stöhr J. - Novotný J. - Bouřová L. - Svoboda P.
Modulation of adenylyl cyclase activity in young and adult rat brain cortex. Identification of suramin as a direct inhibitor of adenylyl cyclase.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 9(4), 940-952, 2005
IF = 3.606(05)

7.
Holáň V. - Pindjáková J. - Zajícová A. - Krulová M. - Železná B. - Matoušek P. - Svoboda P.
The activity of inducible nitric oxide synthase in rejected skin xenografts is selectively inhibited by a factor produced by grafted cells.
Xenotransplantation, 12(3), 227-234, 2005
IF = 2.114(05)

2004

1.
Moravcová Z. - Rudajev V. - Stöhr J. - Novotný J. - Černý J. - Parenti M. - Milligan G. - Svoboda P.
Long-term agonist stimulation of IP prostanoid receptor depletes the cognate G(s)alpha protein in membrane domains but does not change the receptor level.
Biochimica et Biophysica Acta-Molecular Cell Research, 1691(1), 51-65, 2004
IF = 3.482(04)

2.
Stöhr J. - Bouřová L. - Hejnová L. - Ihnatovych I. - Novotný J. - Svoboda P.
Increased baclofen-stimulated G protein coupling and deactivation in rat brain cortex during development.
Developmental Brain Research, 151(1-2), 67-73, 2004
IF = 1.854(04)

3.
Mazna P. - Obšilová V. - Jelínková I. - Balík A. - Berka K. - Sovová Ž. - Ettrich R. - Svoboda P. - Obšil T. - Teisinger J.
Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.
Journal of Neurochemistry, 91(4), 836-842, 2004
IF = 4.824(04)

4.
Matoušek P. - Novotný J. - Svoboda P.
Resolution of G(s)alpha and G(q)alpha/G(11)alpha proteins in membrane domains by two-dimensional electrophoresis: the effect of long-term agonist stimulation.
Physiological Research, 53(3), 295-303, 2004
IF = 1.14(04)

5.
Svoboda P. - Teisinger J. - Novotný J. - Bouřová L. - Drmota T. - Hejnová L. - Moravcová Z. - Lisý V. - Rudajev V. - Stöhr J. - Vokurková A. - Švandová I. - Durchánková D.
Biochemistry of transmembrane signaling mediated by trimeric G proteins.
Physiological Research, 53(Suppl. 1), S141-S152, 2004
IF = 1.14(04)

6.
Šťastný F. - Lisý V. - Mareš V. - Lisá V. - Balcar V.J. - Santamaría A.
Quinolinic acid induced NMDA receptor-mediated lipid peroxidation in rat brain microvessels.
Redox Report, 9(4), 229-233, 2004
IF = 1.724(04)

2003

1.
Matoušek P. - Hodný Z. - Švandová I. - Svoboda P.
Different methods of membrane domains isolation result in similar 2-D distribution patterns of membrane domain proteins.
Biochemistry and Cell Biology, 81(6), 365-372, 2003
IF = 2.456(03)

2.
Hrbasová M. - Novotný J. - Hejnová L. - Kolář F. - Neckář J. - Svoboda P.
Altered myocardial Gs protein and adenylyl cyclase signaling in rats exposed to chronic hypoxia and normoxic recovery.
Journal of Applied Physiology, 94(6), 2423-2432, 2003
IF = 3.027(03)

3.
Bouřová L. - Koštrnová A. - Hejnová L. - Moravcová Z. - Moon H.E. - Novotný J. - Milligan G. - Svoboda P.
Delta-Opioid receptors exhibit high efficiency when activating trimeric G proteins in membrane domains.
Journal of Neurochemistry, 85(1), 34-49, 2003
IF = 4.825(03)

4.
Novotný J. - Hrbasová M. - Kolář F. - Svoboda P.
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
Molecular and Cellular Biochemistry, 245(1-2), 157-166, 2003
IF = 1.763(03)

2002

1.
Johannessen E.A. - Weaver J.M.R. - Bouřová L. - Svoboda P. - Cobbold P.H. - Cooper J.M.
Micromachined nanocalorimetric sensor for ultra-low-volume cell-based assays.
Analytical Chemistry, 74(9), 2190-2197, 2002
IF = 5.094(02)

2.
Flachs P. - Novotný J. - Baumruk F. - Bardová K. - Bouřová L. - Mikšík I. - Šponarová J. - Svoboda P. - Kopecký J.
Impaired noradrenaline-induced lipolysis in white fat of aP2-Ucp1 transgenic mice is associated with changes in G-protein levels.
Biochemical Journal, 364(2), 369-376, 2002
IF = 4.589(02)

3.
Svoboda P. - Novotný J.
Hormone-induced subcellular redistribution of trimeric G proteins.
Cellular and Molecular Life Sciences, 59(3), 501-512, 2002
IF = 5.259(02)

4.
Ihnatovych I. - Novotný J. - Haugvicová R. - Bouřová L. - Mareš P. - Svoboda P.
Opposing changes of trimeric G protein levels during ontogenetic development of rat brain.
Developmental Brain Research, 133(1), 57-67, 2002
IF = 1.562(02)

5.
Ihnatovych I. - Novotný J. - Haugvicová R. - Bouřová L. - Mareš P. - Svoboda P.
Ontogenetic development of the G protein-mediated adenylyl cyclase signalling in rat brain.
Developmental Brain Research, 133(1), 69-75, 2002
IF = 1.562(02)

6.
Šťastný F. - Schwendt M. - Lisý V. - Ježová D.
Main subunits of ionotropic glutamate receptors are expressed in isolated rat brain microvessels.
Neurological Research, 24(1), 93-96, 2002
IF = 0.969(02)

7.
Hejnová L. - Ihnatovych I. - Novotný J. - Kubová H. - Mareš P. - Svoboda P.
Modulation of adenylyl cyclase activity by baclofen in the developing rat brain: difference between cortex, thalamus and hippocampus.
Neuroscience Letters, 330(1), 9-12, 2002
IF = 2.1(02)

8.
Lisý V. - Šťastný F.
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.
Physiological Research, 51(3), 299-307, 2002
IF = 0.984(02)

2001

1.
Kotyk A. - Ihnatovych I. - Lapathitis G. - Lamash N. - Svoboda P.
Subcellular shifts of trimeric G-proteins following activation of baker’s yeast by glucose.
Folia Microbiologica, 46(5), 391-396, 2001
IF = 0.776(01)

2.
Novotný J. - Bouřová L. - Kolář F. - Svoboda P.
Membrane-bound and cytosolic forms of heterotrimeric G proteins in young and adult rat myocardium: influence of neonatal hypo- and hyperthyroidism.
Journal of Cellular Biochemistry, 82(2), 215-224, 2001
IF = 2.536(01)

3.
Ihnatovych I. - Hejnová L. - Koštrnová A. - Mareš P. - Svoboda P. - Novotný J.
Maturation of rat brain is accompanied by differential expression of the long and short splice variants of G(s)alpha protein: identification of cytosolic forms of G(s)alpha.
Journal of Neurochemistry, 79(1), 88-97, 2001
IF = 4.834(01)

4.
Santamaria A. - Galván-Arzate S. - Lisý V. - Ali S.F. - Duhart H.M. - Osorio-Rico L. - Rios C. - Šťastný F.
Quinolinic acid induces oxidative stress in rat brain synaptosomes.
Neuroreport, 12(4), 871-874, 2001
IF = 2.374(01)

2000

1.
Bouřová L. - Pešanová Z. - Novotný J. - Bengtsson T. - Svoboda P.
Differentation of cultured brown adipocytes is associated with a selective increase in the short variant of Gsalfa protein. Evidence for higher functional activity of GsalfaS.
Molecular and Cellular Endocrinology, 167(1-2), 23-31, 2000
IF = 2.369(00)

1999

1.
Drmota T. - Novotný J. - Gould G.W. - Svoboda P. - Milligan G.
Visualization of distinct patterns of subcellular redistribution of the thyrotropin-releasing hormone receptor-1 and Gq alpha/G11 alpha induced by agonist stimulation.
Biochemical Journal, 340, 529-538, 1999
IF = 4.349(99)

2.
Pešanová Z. - Novotný J. - Černý J. - Milligan G. - Svoboda P.
Thyrotropin-releasing hormone-induced depletion of Gq alpha/G11 alpha proteins from detergent-insensitive membrane domains.
FEBS Letters, 464(1-2), 35-40, 1999
IF = 3.72(99)

3.
Novotný J. - Bouřová L. - Málková O. - Svoboda P. - Kolář F.
G proteins, beta-adrenoreceptors and beta-adrenergic responsiveness in immature and adult rat ventricular myocardium: Influence of neonatal hypo- and hyperthyroidism.
Journal of Molecular and Cellular Cardiology, 31, 761-772, 1999
IF = 2.923(99)

4.
Bouřová L. - Novotný J. - Svoboda P.
The decrease in the short variant of Gs alpha protein is associated with an increase in [3H]CGP12177 binding, [3H]ouabain binding and Na,K- ATPase activity in brown adipose tissue plasma membranes of cold-acclimated hamsters.
Journal of Molecular Endocrinology, 22, 55-64, 1999
IF = 2.331(99)

5.
Bouřová L. - Novotný J. - Svoboda P.
Resolution and identification of Gg/G11alpha and Gialpha/Goalpha proteins in brown adipose tissue: effect of cold acclimation.
Journal of Molecular Endocrinology, 23(2), 223-229, 1999
IF = 2.331(99)

6.
Novotný J. - Krůšek J. - Drmota T. - Svoboda P.
Overexpression of the G protein G11 alpha prevents desensitization of Ca2+ response to thyrotropin-releasing hormone.
Life Sciences, 65(9), 889-900, 1999
IF = 1.774(99)

1998

1.
Schooning K. - Bolmstedt A. - Novotný J. - Lund O.S. - Olofsson S. - Hansen J.E.S.
Induction of antibodies against epitopes inaccessible on the HIV type 1 envelope oligomer by immunization with recombinant monomeric glycoprotein 120.
Aids Research and Human Retroviruses, 14(16), 1451-1456, 1998
IF = 2.609(98)

2.
Drmota T. - Novotný J. - Kim G.D. - Eidne K.A. - Milligan G. - Svoboda P.
Agonist-induced internalization of the G protein G11alpha and thyrotropin-releasing hormone receptors proceed on different time scales.
Journal of Biological Chemistry, 273(34), 21699-21707, 1998
IF = 7.199(98)

3.
Novotný J. - Svoboda P.
The long (Gsalpha-L) and short (Gsalpha-S) variants of the stimulatory guanine nucleotide-binding protein. Do they behave in an identical way?
Journal of Molecular Endocrinology, 20(2), 163-173, 1998
IF = 1.88(98)

1997

1.
Šťastný F. - Dvořáková L. - Lisý V.
Biochemical characteristics of gamma-glutamyl transpeptidase in capillaries from entorhinohippocampal complex of quinolinate-lesioned rat brain.
Molecular and Chemical Neuropathology, 32, 143-161, 1997
IF = 0.78(97)

2.
Folbergrová J. - Lisý V. - Haugvicová R. - Šťastný F.
Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: Effect of homocysteine-induced seizures.
Neurochemical Research, 22(5), 637-646, 1997
IF = 1.31(97)

1996

1.
Svoboda P. - Unelius L. - Dicker A. - Cannon B. - Milligan G. - Nedergaard J.
Cold-induced reduction in GiÓ proteins in brown adipose tissue. Effects on the cellular hypersensitization to noradrenaline caused by pertussis-toxin treatment.
Biochemical Journal, 314(3), 761-768, 1996
IF = 3.687(96)

2.
Dvořáková L. - Krůšek J. - Šťastný F. - Lisý V.
Relationship between kinetic properties of gamma-glutamyl transpeptidase and the structure of its saccharide moiety.
Biochimica et Biophysica Acta, 1292(1), 163-167, 1996
IF = 2.43(96)

3.
Dvořáková L. - Krůšek J. - Šťastný F. - Lisý V.
Analysis of kinetic properties of gamma-glutamyl transpeptidase from rat kidney.
General Physiology and Biophysics, 15, 403-413, 1996
IF = 0.349(96)

4.
Svoboda P. - Kim G.D. - Grassie M.A. - Eidne K.A. - Milligan G.
Thyrotropin-releasing hormone-induced subcellular redistribution and down-regulation of G11 alpha: Analysis of agoinst regulation of coexpressed G11 alpha species variants.
Molecular Pharmacology, 49(4), 646-655, 1996
IF = 6.58(96)

5.
Mullaney I. - Caulfield M.P. - Svoboda P. - Milligan G.
Activation, cellular redistribution and enhanced degradation of the G proteins Gq and G11 by endogenously expressed and transfected phospholipase C-coupled muscarinic m1 acetylcholine receptors.
Progress in Brain Research, 109, 181-187, 1996
IF = 1.488(96)

1995

1.
Milligan G. - Wise A. - MacEvan D.J. - Grassie M.A. - Kennedy F.R. - Lee T.W. - Adie E.J. - Kim G.D. - MacCallum F.J. - Burt A. - Carr I.C. - Svoboda P. - Shah B.H. - Mullaney I.
Mechanisms of agoinst-induced G-protein elimination.
Biochemical Society Transactions, 23, 166-170, 1995
IF = 1.275(95)

2.
Hejnová L. - Tuček S. - El-Fakahany E.E.
Positive and negative allosteric interactions on muscarinic receptors.
European Journal of Pharmacology, 291, 427-430, 1995
IF = 2.637(95)

3.
Kunclová D. - Liška V. - Svoboda P. - Svobodová J.
Cold-shock response of protein, RNA, DNA and phospholipid synthesis in bacillus subtilis.
Folia Microbiologica, 40(6), 627-632, 1995
IF = 0.147(95)

4.
Svobodová J. - Konopásek I. - Kaprálek F. - Svoboda P.
Effect of benzyl alcohol and ethanol on cold-shock response of bacillus subtilis.
Folia Microbiologica, 40(6), 633-638, 1995
IF = 0.147(95)

1994

1.
Milligan G. - Svoboda P. - Brown CH. M.
Why are there so many adrenoreceptor subtypes?
Biochemical Pharmacology, 48(6), 1059-1071, 1994
IF = 2.263(94)

2.
Dvořáková L. - Šťastný F. - Lisý V.
Relationship between gamma-glutamyl transpeptidase activity and sialic acid content in some organs and brain regions of the developing rat.
Biochemistry and Molecular Biology International, 34(6), 1137-1145, 1994
IF = 0.566(94)

3.
Kvapil P. - Novotny J. - Svoboda P. - Rannsnäs L. A.
The short and long forms of the Ó subunit of the stimulatory guanine-nucleotide-binding protein are unequally redistributed during (-)-isoproterenol-mediated desensitization of intact S49 lymphoma cells.
European Journal of Biochemistry, 226(1), 193-199, 1994
IF = 3.578(94)

4.
Svoboda P. - Milligan G.
Agonist-induced transfer of the Ó subunits of the guanine-nucleotide-binding regulatory proteins G+q and G+11 and of muscarinic m1 acetylcholine receptors from plasma membranes to a light-vesicular membrane fraction.
European Journal of Biochemistry, 224(2), 455-462, 1994
IF = 3.578(94)

5.
Lisý V. - Dvořáková L. - Šťastný F.
Altered Glutamate Binding Following Qionolinate Lesions in Developing Rat Brain.
Experimental Neurology, 125(1), 82-86, 1994
IF = 2.803(94)

1993

1.
Svoboda P. - Unelius L. - Cannon B. - Nedergaard J.
Attenuation of G+S Ó coupling efficiency in brown-adipose-tissue plasma membranes from cold-acclimated hamsters.
Biochemical Journal, 295(3), 655-661, 1993
IF = 3.659(93)

2.
Lisý V. - Šťastný F.
Effect of repeated hyperammonemia on Na++-dependent binding of glutamate in rat cortical and hippocampal synaptic membranes.
Neuroscience Letters, 158(1), 113-116, 1993
IF = 2.645(93)