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30.9.2011 - Theta-paced flickering between place-cell maps in the hippocampus. Nature 2011

Article published in prestige journal–Nature (IF=34.1)Jezek, K.-Henriksen, E.J.-Treves, A.–Moser, E.I.- Moser, M-B. Theta-paced flickering between place-cell maps in the hippocampus. Nature, published online 28 September 2011, doi:10.1038/nature10439

The paper describes process of switching between two memory states in hippocampus. Analysis in high temporal resolution showed that after stimulus change, the original and new memory often compete before the later one gets stabilized. The study identifies hippocampal theta oscillation as pacemaker controlling this process. It showes that neuronal patterns of activity (believed to be neuronal substrates of memory) are expressed in quantal units or packets, once every cca 125 miliseconds. This allows the memory system to constantly reprocess the incoming stimuli and express the proper activity pattern in order to facilitate error correction and enhance discriminative power in the presence of weak and ambiguous input cues.

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature10439.html

Author: karel.jezek@biomed.cas.cz




01.1.2013 - BIOCEV
BIOTECHNOLOGY AND BIOMEDICINE CENTER OF THE ACADEMY OF SCIENCES AND CHARLES UNIVERSITY IN VESTEC

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31.1.2012 - Post doctoral positions
The Center of Biomedical Research, Institute of Physiology, Academy of Sciences, Prague, Videnska 1083, 14220, Czech Republic is seeking applicants for eight Post doctoral positions,

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16.11.2011 - The Josef Hlávka Medal
Prof. RNDr. František Vyskočil, DSc., has been awarded the Josef Hlávka Medal

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19.9.2011 - Yeast Physiology
Czech- Spanish workshop, September 19

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04.7.2011 - The Honourable Mention of Mensa
Prof. Helena Illnerová, DSc, has been awarded by The Honourable Mention of Mensa

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07.6.2011 - The J. E. Purkyně Honorary Medal
Prof. RNDr. František Vyskočil, DSc, has been awarded by The Jan Evangelista Purkyně Honorary Medal

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01.6.2011 - RNDr. Lydie Plecitá-Hlavatá, PhD, and Mgr, Martin Horák, Ph.D. were awarded the Otto Wichterle Prem
RNDr. Lydie Plecitá-Hlavatá, PhD, and Mgr. Martin Horák, PhD, were awarded the Otto Wichterle Premium

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25.5.2011 - PharmDr, Alena Sumová, DSc, has been awarded by the Lauberger Medal
PharmDr. Alena Sumová, DSc, has been awarded by the Lauberger Medal

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25.5.2011 - Josef Zicha, MD, DSc,
has been awarded by Honourable membership in CzPA JEP

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25.5.2011 - Prof. Bohuslav Ostadal, MD, DSc, has been awarded by the Purkyně Gold Medal of CzMA
Prof. Bohuslav Ostadal, MD, DSc, has been awarded by the Purkyně Gold Medal of CzMA

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