2012

Holakovska B, Grycova L, Jirku M, Sulc M, Bumba L, Teisinger J.

Calmodulin and S100A1 interact with N-terminus of TRPM3 channel.

J Biol Chem. 2012 March 26

IF = 5.328(11)

Veisova D, Macakova E, Rezabkova L, Sulc M, Vacha P, Sychrova H, Obsil T, Obsilova V.

Role of individual phosphorylation sites for the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.

Biochem J. 2012 Feb 9.

IF = 5.016(11)

2011

Rezabkova L, Man P, Novak P, Herman P, Vecer J, Obsilova V, Obsil T.

Structural basis for the 14-3-3 protein-dependent inhibition of the regulator of G-Protein signaling 3 (RGS3) function.

J Biol Chem. 2011 Dec 16;286(50):43527-36.

IF = 5.328(11)

Obsil T, Obsilova V.:

Structural basis of 14-3-3 protein functions.

Semin Cell Dev Biol. 2011 Sep;22(7):663-72.  

IF = 6.342(10)

Obsil T, Obsilova V.

Structural basis for DNA recognition by FOXO proteins.

Biochim Biophys Acta. 2011 Nov;1813(11):1946-53.

IF = 4.374(10)

Coddou C, Yan Z, Obsil T, Huidobro-Toro JP, Stojilkovic SS.

Activation and regulation of purinergic P2X receptor channels.

Pharmacol Rev. 2011 Sep;63(3):641-83.

IF = 18.861(10)

Valis K, Prochazka L, Boura E, Chladova J, Obsil T, Rohlena J, Truksa J, Dong LF, Ralph SJ, Neuzil J.

Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner.

Cancer Res. 2011 Feb 1;71(3):946-54.

IF = 7.543(10)

Touska F, Marsakova L, Teisinger J, Vlachova V.

A "Cute" Desensitization of TRPV1.

Curr Pharm Biotechnol. 12(1):122-9. Review. 2011

IF = 3.455(10)

Samad A, Sura L, Benedikt J, Ettrich R, Minofar B, Teisinger J, Vlachova V.

The C-terminal basic residues contribute to the chemical and voltage-dependent activation of TRPA1.

Biochem J. 433(1):197-204. 2011

IF = 5.016(10)

Holakovska B, Grycova L, Bily J, Teisinger J.

Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails.

Amino Acids 40(2):741-8. 2011

IF = 4.106(10)

2010

Stojilkovic SS, Yan Z, Obsil T, Zemkova H.

Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.

Cell Mol Neurobiol. 2010 Nov;30(8):1251-8.

IF = 3.226(09)

Veisova, D., Rezabkova, L., Stepanek, M., Novotna, P., Herman, P., Vecer, J., Obsil, T., Obsilova, V.

C-terminal segment of yeast BMH proteins exhibits different structure compared to other 14-3-3 protein isoforms.

Biochemistry 49(18), 3853-3861, 2010

IF = 3.226(09)

Rezabkova, L., Boura, E., Herman, P., Vecer, J., Bourova, L., Sulc, M., Svoboda, P., Obsilova, V., Obsil

14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G-protein signaling 3 (RGS3).

J. Struct. Biol. 170(3), 451-461, 2010

IF = 3.673(09)

Boura E, Rezabkova L, Brynda J, Obsilova V, Obsil T.:

Crystal structure of human FOXO4-DBD/DNA complex at 1.9 A resolution reveals new details on FOXO binding to the DNA

Acta Crystallographica Section D, 2010 [Epub ahead of print].

IF = 6.326(10)

Friedlova E, Grycova L, Holakovska B, Silhan J, Janouskova H, Sulc M, Obsilova V, Obsil T, Teisinger J.

The interactions of the C-terminal region of the TRPC6 channel with calmodulin.

Neurochem Int. 2010 Jan;56(2):363-6.

IF = 3.541(09)

Boukalova S, Marsakova L, Teisinger J, Vlachova V.

Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive TRPV channels.

J Biol Chem. 285(53):41455-62. 2010

IF = 5.328(09)

Rokic M, Tvrdonova V, Vavra V, Jindrichova M, Obsil T, Stojilkovic SS, Zemkova H.

Roles of conserved ectodomain cysteines of the rat P2X4 purinoreceptor in agonist binding and channel gating.

Physiol Res. 59(6):927-35. 2010

IF = 1.653(08)

2009

Gryčová L. - Sklenovský P. - Lánský Z. - Janovská M. - Otyepka M. - Amler E. - Teisinger J. - Kubala M.

ATP and magnesium drive conformational changes of the Na+/K+-ATPase cytoplasmic headpiece.

Biochimica Et Biophysica Acta-Biomembranes, 1788(5), 1081-1091, 2009
IF = 4.18(08)

Benedikt J. - Samad A. - Ettrich R. - Teisinger J. - Vlachová V.
Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

Biochimica Et Biophysica Acta-Molecular Cell Research, 1793(7), 1279-1288, 2009
IF = 4.893(08)

Kubala M. - Gryčová L. - Lánský Z. - Sklenovský P. - Janovská M. - Otyepka M. - Teisinger J.
Changes in electrostatic surface potential of Na+/K+-ATPase cytoplasmic headpiece induced by cytoplasmic ligand(s) binding.

Biophysical Journal, 97(6), 1756-1764, 2009
IF = 4.683(08)

Šilhán J. - Vácha P. - Strnadová P. - Večeř J. - Herman P. - Šulc M. - Teisinger J. - Obšilová V. - Obšil T.
14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.
Journal of Biological Chemistry, 284(29), 19349-19360, 2009
IF = 5.52(08)

Jindřichová M. - Vávra V. - Obšil T. - Stojilkovic S. S. - Zemková H.
Functional relevance of aromatic residues in the first transmembrane domain of P2X receptors.
Journal of Neurochemistry, 109(3), 923-934, 2009
IF = 4.5(08)

2008

Gryčová L. - Lánský Z. - Friedlová E. - Obšilová V. - Janoušková H. - Obšil T. - Teisinger J.
Ionic interactions are essential for TRPV1 C-terminus binding to calmodulin.

Biochemical and Biophysical Research Communications, 375(4), 680-683, 2008
IF = 2.648(08)

Obšilová V. - Nedbálková E. - Šilhán J. - Bouřa E. - Herman P. - Večeř J. - Šulc M. - Teisinger J. - Dyda F. - Obšil T.
The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase.

Biochemistry, 47(6), 1768-1777, 2008
IF = 3.379(08)

Mazna P. - Gryčová L. - Balík A. - Zemková H. - Friedlová E. - Obšilová V. - Obšil T. - Teisinger J.
The role of proline residues in the structure and function of human MT2 melatonin receptor

Journal of Pineal Research, 45(4), 361-372, 2008
IF = 5.056(08)

Obšil T. - Obšilová V.
Structure/function relationships underlying regulation of FOXO transcription factors.
Oncogene, 27(16), 2263-2275, 2008
IF = 7.216(08)

Jelínková I. - Vávra V. - Jindřichová M. - Obšil T. - Zemková H.W. - Zemková H. - Stojilkovic S. S.
Identification of P2X(4) receptor transmembrane residues contributing to channel gating and interaction with ivermectin.

Pflügers Archiv, 465(5), 939-950, 2008
IF = 3.526(08)

Obsilová V, Silhan J, Boura E, Teisinger J, Obsil T.

14-3-3 proteins: a family of versatile molecular regulators.

Physiol Res. 57 Suppl 3:S11-21, 2008. Review.

IF = 1.653(08)

Drastichová Z. - Bouřová L. - Lisý V. - Hejnová L. - Rudajev V. - Stöhr J. - Durchánková D. - Ostašov P. - Teisinger J. - Soukup T. - Novotný J. - Svoboda P.
Subcellular redistribution of trimeric G-proteins--potential mechanism of desensitization of hormone response: internalization, solubilization, down-regulation.

Physiological Research, 57, S1-S10, 2008
IF = 1.653(08)

2007

Gryčová L. - Lánský Z. - Friedlová E. - Vlachová V. - Kubala M. - Obšilová V. - Obšil T. - Teisinger J.
ATP binding site on the C-terminus of the vanilloid receptor.

Archives of Biochemistry and Biophysics, 465(2), 389-398, 2007
IF = 2.578(07)

Bouřa E. - Šilhán J. - Herman P. - Večeř J. - Teisinger J. - Obšilová V. - Obšil T.
Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding.

Journal of Biological Chemistry, 282(11), 8265-8275, 2007
IF = 5.581(07)

Benedikt J. - Teisinger J. - Vyklický ml. L. - Vlachová V.
Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate.

Journal of Neurochemistry, 100(1), 211-224, 2007
IF = 4.451(07)

Zemková H. - Yan Z. - Liang Z. - Jelínková I. - Tomič M. - Stojilkovic S. S.
Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions.
Journal of Neurochemistry, 102(4), 1139-1150, 2007
IF = 4.451(07)

Sušánková K. - Ettrich R. - Vyklický st. L. - Teisinger J. - Vlachová V.
Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).

Journal of Neuroscience, 27(28), 7578-7585, 2007
IF = 7.49(07)

Nováková-Toušová K. - Vyklický st. L. - Sušánková K. - Benedikt J. - Samad A. - Teisinger J. - Vlachová V.
Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization.

Neuroscience, 149(1), 144-154, 2007
IF = 3.352(07)

2006

Jelínková I. - Yan Z. - Liang Z. - Moonat S. - Teisinger J. - Stojilkovic S. S. - Zemková H.
Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation.

Biochemical and Biophysical Research Communications, 349(2), 619-625, 2006
IF = 2.855(06)

Sušánková K. - Toušová K. - Vyklický st. L. - Teisinger J. - Vlachová V.
Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current.

Molecular Pharmacology, 70(1), 383-394, 2006
IF = 4.469(06)

2005

Mazna P. - Berka K. - Jelínková I. - Balík A. - Svoboda P. - Obšilová V. - Obšil T. - Teisinger J.
Ligand binding to the human MT2 melatonin receptor: the role of residues in transmembrane domains 3, 6, and 7.

Biochemical and Biophysical Research Communications, 332(3), 726-734, 2005
IF = 3(05)

Obšilová V. - Večeř J. - Herman P. - Pabiánová A. - Šulc M. - Teisinger J. - Bouřa E. - Obšil T.
14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.

Biochemistry, 44(34), 11608-11617, 2005
IF = 3.848(05)

2004

Lánský Z. - Kubala M. - Ettrich R. - Kutý M. - Plášek J. - Teisinger J. - Schoner W. - Amler E.
The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.

Biochemistry, 43(26), 8303-8311, 2004
IF = 4.008(04)

Obšilová V. - Herman P. - Večeř J. - Šulc M. - Teisinger J. - Obšil T.
14-3-3zeta C-terminal stretch changes its conformation upon ligand binding and phosphorylation at Thr232.

Journal of Biological Chemistry, 279(6), 4531-4540, 2004
IF = 6.355(04)

Šilhan J. - Obšilová V. - Večeř J. - Herman P. - Šulc M. - Teisinger J. - Obšil T.
14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding.

Journal of Biological Chemistry, 279(47), 49113-49119, 2004
IF = 6.355(04)

Mazna P. - Obšilová V. - Jelínková I. - Balík A. - Berka K. - Sovová Ž. - Ettrich R. - Svoboda P. - Obšil T. - Teisinger J.
Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.

Journal of Neurochemistry, 91(4), 836-842, 2004
IF = 4.824(04)

Toušová K. - Sušánková K. - Teisinger J. - Vyklický st. L. - Vlachová V.
Oxidizing reagent copper-o-phenanthroline is an open channel blocker of the vanilloid receptor TRPV1.

Neuropharmacology, 47(2), 273-285, 2004
IF = 3.734(04)

Kubala M. - Obšil T. - Obšilová V. - Lánský Z. - Amler E.
Protein modeling combined with spectroscopic techniques: an attractive quick alternative to obtain structural information.

Physiological Research, 53(Suppl. 1), S187-S197, 2004
IF = 1.14(04)

Svoboda P. - Teisinger J. - Novotný J. - Bouřová L. - Drmota T. - Hejnová L. - Moravcová Z. - Lisý V. - Rudajev V. - Stöhr J. - Vokurková A. - Švandová I. - Durchánková D.
Biochemistry of transmembrane signaling mediated by trimeric G proteins.
Physiological Research, 53(Suppl. 1), S141-S152, 2004
IF = 1.14(04)

2003

Krumscheid R. - Sušánková K. - Ettrich R. - Teisinger J. - Amler E. - Schoner W.
Localization of catalytic active sites in the large cytoplasmic domain of Na+/K+-ATPase.

Annals of the New York Academy of Sciences, 986(-), 242-244, 2003
IF = 1.892(03)

Hofbauerová K. - Kopecký ml. V. - Ettrich R. - Kubala M. - Teisinger J. - Amler E.
ATP-binding is stabilized by a stacking interaction within the binding site of Na+/K+ -ATPase.

Biochemical and Biophysical Research Communications, 306(2), 416-420, 2003
IF = 2.836(03)

Kubala M. - Teisinger J. - Ettrich R. - Hofbauerová K. - Kopecký ml. V. - Baumruk V. - Krumscheid R. - Plášek J. - Schoner W. - Amler E.
Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.
Biochemistry, 42(21), 6446-6452, 2003
IF = 3.922(03)

Vlachová V. - Teisinger J. - Sušánková K. - Lyfenko A. - Ettrich R. - Vyklický st. L.
Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1.

Journal of Neuroscience, 23(4), 1340-1350, 2003
IF = 8.306(03)

2002

Kubala M. - Hofbauerová K. - Ettrich R. - Kopecký ml. V. - Krumscheid R. - Plášek J. - Teisinger J. - Schoner W. - Amler E.
Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase.

Biochemical and Biophysical Research Communications, 297(1), 154-159, 2002
IF = 2.935(02)

Abdrachmanova G. - Teisinger J. - Vyklický ml. L.
Molecular and functional properties of synaptically activated NMDA receptors in neonatal motoneurons in rat spinal cord slices.
Journal of Physiology, 538(1), 53-63, 2002
IF = 4.65(02)

Vyklický st. L. - Lyfenko A. - Sušánková K. - Teisinger J. - Vlachová V.
Reducing agent dithiothreitol facilitates activity of the capsaicin receptor VR-1.

Neuroscience, 111(3), 435-441, 2002
IF = 3.457(02)