1. Cellular and molecular mechanisms of pain transmission and modulation at spinal cord level.

2. The role of dorsal column pathway and postsynaptic dorsal column neurons in visceral pain.

3. Effect of exo- and endogenous factors on muscle differentiation, mRNA and protein isoforms of contractile and Ca 2+ transporting proteins.

4. Morphological substrate of muscle pain, properties and distribution of nociceptive primary afferent fibres in fast and slow skeletal muscles.

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