Selected recent publications of Laboratory of Eye Histochemistry and Pharmacology

  

1. Čejková J, Vejražka M, Pláteník J, Štípek S. (2004) Age-related changes in superoxide dismutase, glutathione peroxidase, catalase and xanthine oxidoreductase/xanthine oxidase activities in the rabbit cornea. Exp Gerontol 39: 1537–1543.

 

2. Tessem MB, Bathen TF, Čejková J, Midelfart A. (2005) Effect of UV-A and UV-B irradiation on the metabolic profile of aqueous humor in rabbits analyzed by 1H NMR spectroscopy. Invest Ophthalmol Vis Sci 46: 776–781.

 

3. Fris M, Tessem MB, Čejková J, Midelfart A. (2006) The effect of single and repeated UVB radiation on rabbit cornea. Graefes Arch Clin Exp Ophthalmol 244: 1680–1687.

 

4. Čejka Č, Pláteník J, Guryca V, Širc J, Michálek J, Brůnová B, Čejková J. (2007) Light absorption properties of the rabbit cornea repeatedly irradiated with UVB rays. Photochem Photobiol 83: 652–657.

 

5. Čejková J, Ardan T, Šimonová Z, Čejka Č, Malec J, Dotřelová D, Brůnová B. (2008) Decreased expression of antioxidant enzymes in the conjunctival epithelium of dry eye (Sjögren´s syndrome) and its possible contribution to the development of ocular surface oxidative injuries. Histol Histopathol 23: 1477–1483.

 

6. Čejka Č, Pláteník, J, Buchal R, Guryca V, Širc J, Vejražka M, Crkovská J, Ardan T, Michálek J, Brůnová B, Čejková J. (2009) Effect of two different UVA doses on the rabbit cornea and lens. Photochem Photobiol 85: 794–800.

 

7. Čejková J, Ardan T, Čejka Č, Malec J, Jirsová K, Filipec M, Růžičková E, Dotřelová D, Brůnová B. (2009) Ocular surface injuries in autoimmune dry eye. The severity of microscopical disturbances goes parallel with the severity of symptoms of dryness. Histol Histopathol 24: 1357-1365.

 

8. Čejková J, Čejka Č, Ardan T, Širc J, Michálek J, Luyckx J (2010) Reduced UVB-induced corneal damage caused by reactive oxygen and nitrogen species and decreased changes in corneal optics after trehalose treatment. Histol Histopathol 25, 1403-1416.

9. Čejka Č, Luyckx J, Ardan T, Pláteník J, Širc J, Michálek J, Čejková J (2010) The effect of actinoquinol with hyaluronic acid in eye drops on the optical properties and oxidative damage of the rabbit cornea irradiated with UVB rays. Photochem Photobiol 86, 1294-1306.

10. Čejka Č, Ardan T, Širc J, Michálek J, Brůnová B, Čejková J (2010) The influence of various toxic effects on the cornea and changes in corneal light transmission. Graefes Arch Clin Exp Ophthalmol 248, 1749-1756.

11. Čejka Č, Pláteník J, Širc J, Ardan T, Michálek J, Brůnová B, Čejková J(2010) Changes of corneal optical properties after UVB irradiation investigated spectrophotometrically. Physiol Res 59, 591-597.

12. Čejka Č, Ardan T, Širc J, Michálek J, Beneš J, Brůnová B, Rosina J (2011) Hydration and transparency of the rabbit cornea irradiated with UVB-doses of 0.25 J/cm2 and 0.5 J/cm2 compared with equivalent UVB radiation exposure reaching the human cornea from sunlight. Curr Eye Res 36, 607-613.

13. Čejková J, Ardan T, Čejka Č, Luyckx J (2011) Favourable effects of trehalose on the development of UVB-mediated antioxidant/prooxidant imbalance in the corneal epithelium, proinflammatory cytokine and matrix metalloproteinase induction, and heat shock protein 70 expression. Graefes Arch Clin Exp Ophthalmol 249, 1185-1194.

14. Cejka C, Luyckx J, Cejkova J (2012) Central corneal thickness considered an index of corneal hydration of the UVB irradiated rabbit cornea as influenced by UVB absorber. Physiol Res 61, 299-306.

15. Cejkova J, Cejka C, Luyckx J (2012) Trehalose treatment accelerates the healing of UVB-irradiated corneas. Comparative immunohistochemical studies on corneal cryostat sections and corneal impression cytology. Histol Histopathol 27, 1029-1040.

16. Cejka C, Rosina J, Sirc J, Michalek J, Brunova B, Cejkova C (2013) The reversibility of UV-B inducec alterations in optical properties of the rabbit cornea depends on dose of UV irradiation. Photochem Photobiol 89, 474-482.

17. Cejkova J, Olmiere C, Cejka C, Trosan P, Holan V (2013) The healing of alkali-injured cornea is stimulated by a novel matrix regenerating agent (RGTA, CACICOL20): a biopolymer mimicking heparan sulfates reducing proteolytic, oxidative and nitrosative damage. (Epub ahead of print).

18. Cejkova J, Trosan P, Cejka C, Lencova A, Zajicova A, Javorkova R, Kubinova S, Sykova E, Holan V (2013) Suppression of alkali-induced oxidative injury in the cornea by mesenchymal stem cells growing on nanofiber scaffolds and transferred onto the damaged corneal surface. Eyp Eye Res 116:312-323.