Ing. Martin Kuchař, Ph.D.
e-mail:
kuchar@uochb.cas.cz
Born 17. 9. 1980 in Čáslav (Czech Republic).
Scientific CV:
1999-2004 undergraduate study,
Prague Institute of Chemical Technology, M. S. degree - specialization organic chemistry (supervisor Prof. Svoboda)
2004-2008 PhD study,
Institute of Organic Chemistry and Biochemistry,
Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
Professional membership:
Czech Chemical Society
List of publications:
| 5. |
Kuchař, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: "Synthesis of diverse 6-(1,2-disubstituted ethyl)purine bases and nucleosides via 6-(oxiran-2-yl)purines" Tetrahedron 2008, 64, 10355-10364. |
| 4. |
Nauš, P.; Kuchař, M.; Hocek, M.: "Cytostatic and activiral 6-arylpurine ribonucleosides IX. Synthesis and evaluation of 6-substituted 3-deazapurine ribonuclesides" Collect. Czech. Chem. Commun. 2008, 73, 665-678. |
| 3. |
Kuchař, M.; Pohl, R.; Klepetářová, B.; Votruba, I.; Hocek, M.: "Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations" Org. Biomol. Chem. 2008, 6, 2377-2387. |
| 2. |
Kuchař, M.; Hocek, M.; Pohl, R.; Votruba, I.; Shih, I.; Mabery, E.; Mackman, R.: "Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides" Bioorg. Med. Chem. 2008, 16, 1400–1424. |
| 1. |
Kuchař, M.; Pohl, R.; Votruba, I.; Hocek, M.: "Synthesis of Purines Bearing Functionalized C-Substituents by the Conjugate Addition of Nucleophiles to 6-Vinylpurines and 6-Ethynylpurines" Eur. J. Org. Chem. 2006, 5083-5098. |
