Parazitologický ústav

Biologické centrum AV ČR, v.v.i.

České Budějovice, Česká republika

Prof. RNDr. Julius Lukeš CSc.

Oddělení: Oddělení molekulární parazitologie
Laboratoře: Laboratoř molekulární biologie prvoků
Pozice: Vědecký pracovník
Telefon 1: 5416
Telefon 2:
Email 1: jula@paru.cas.cz
Email 2:
WWW:







Životopis:


Současné publikace:

GULER J.L., KRIEGOVÁ E., SMITH T.K., LUKEŠ J., ENGLUND P.T. (2008) Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei. Molecular Microbiology 67, 1125- 1142.
HASHIMI H., ZÍKOVÁ A., PANIGRAHI A.K., STUART K.D., LUKEŠ J. (2008) TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex. RNA 14, 970- 980.
CHOCHOLOVÁ E., JIRKŮ M., LUKEŠ J. (2008) A diagnostic assay based on variable intergenic region distinguishes between Leishmania donovani and Leishmania infantum. Folia Parasitologica 55, 75- 78.
LAI D.-H., HASHIMI H., LUN Z.-R., AYALA F.J., LUKEŠ J. (2008) Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei. PNAS 105, 1999- 2004.
LONG S., JIRKŮ M., AYALA F.J., LUKEŠ J. (2008) Mitochondrial localization but not processing of human frataxin is essential for a rescue of frataxin deficiency in the excavate flagellate Trypanosoma brucei. PNAS 105, 13468- 13473.
LONG S., JIRKŮ M., MACH J., GINGER M.L., ŠUŤÁK R., RICHARDSON D., TACHEZY J., LUKEŠ J. (2008) Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologs in trypanosomes. Molecular Microbiology 69, 94- 109.
LONG S., VÁVROVÁ Z., LUKEŠ J. (2008) The import and function of diatom and plant frataxins in the mitochondrion of Trypanosoma brucei. Molecular and Biochemical Parasitology 162, 100- 104.
YURCHENKO V.A., LUKEŠ J., TESAŘOVÁ M., JIRKŮ M., MASLOV D.A. (2008) Morphological discordance of the new trypanosomatid species phylogenetically associated with the genus Crithidia. Protist 159, 99- 114.
ZÍKOVÁ A., KOPEČNÁ J., SCHUMACHER M.A., STUART K., TRANTÍREK L., LUKEŠ J. (2008) Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei. International Journal for Parasitology 38, 901- 912.
ČERMÁKOVÁ P., VERNER Z., MAN P., LUKEŠ J., HORVÁTH A. (2007) Characterization of the NADH:ubiquinone oxidoreductase (complex I) in the trypanosomatid Phytomonas serpens (Kinetoplastida). FEBS Journal 274, 3150- 3158.
HERDER S., VOTÝPKA J., JIRKŮ M., RÁDROVÁ J., JANZEN C. J., LUKEŠ J. (2007) Trypanosoma brucei 29-13 strain is inducible in but not permissive for the tsetse fly vector. Experimental Parasitology 117, 111- 114.
LUKEŠ J., MAURICIO I.L., SCHÖNIAN G., DUJARDIN J.-C., SOTERIADOU K., DEDET J.-P., KUHLS K., QUISPE TINTAYA W., JIRKŮ M., CHOCHOLOVÁ E., HARALAMBOUS C., PRATLONG F., OBORNÍK M., HORÁK A., AYALA F.J., MILES M.A. (2007) Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy. Proceedings of the National Academy of Science U.S.A. 104, 9375- 9380.
ROY J., FAKTOROVÁ D., BENADA O., LUKEŠ J., BURGER G. (2007) Description of Rhynchopus euleeides n. sp. (Diplonemea), a free-living, marine euglenozoan. Journal of Eukaryotic Microbiology 54, 137- 145.
ROY J., FAKTOROVÁ D., LUKEŠ J., BURGER G. (2007) Unusual mitochondrial genome structure throughout Euglenozoa. Protist 158, 385- 396.
STURM N.R., DOLLET M., LUKEŠ J., CAMPBELL D.A. (2007) Rational sub-division of plant trypanosomes (Phytomonas spp.) based on minicircle conserved region analysis. Infection, Genetics and Evolution 7, 570- 576.
SVOBODOVÁ M., ZÍDKOVÁ L., ČEPIČKA I., OBORNÍK M., LUKEŠ J., VOTÝPKA J. (2007) Sergeia podlipaevi gen. nov., sp. nov. (Trypanosomatidae, Kinetoplastida): a new parasite of the biting midges (Ceratopogonidae, Diptera). International Journal of Systematic and Evolutionary Microbiology 57, 423- 432.
ZAMUDIO J.R., MITTRA B., FOLDYNOVÁ-TRANTÍRKOVÁ S., ZEINER G.M., LUKEŠ J., BUJNICKY J.M., STURM N.R., CAMPBELL D.A. (2007) The 2’-O-ribose methyltransferase for cap 1 of spliced leader RNA and U1 small nuclear RNA in Trypanosoma brucei. Molecular and Cellular Biology 27, 6084- 6092.
ZEMANOVÁ E., JIRKŮ M., MAURICIO I.L., HORÁK A., MILES M.A., LUKEŠ J. (2007) The Leishmania donovani complex: Genotypes of five metabolic enzymes (ICD, ME, MPI, G6PDH, FH), new targets for multilocus sequence typing. International Journal for Parasitolology 37, 149- 160.
JIRKŮ M., ZEMANOVÁ E., AL-JAWABREH A., SCHÖNIAN G., LUKEŠ J. (2006) Development of a direct species-specific PCR assay for differential diagnosis of Leishmania tropica. Diagnostic Microbiology and Infectious Disease 55, 75- 79.
KOPEČNÁ J., JIRKŮ M., OBORNÍK M., TOKAREV Y.S., LUKEŠ J., MODRÝ D. (2006) Phylogenetic analysis of coccidian parasites from invertebrates: search for missing links. Protist 157, 173- 183.
LI F.-J., LAI D.-H., LUKEŠ J., CHEN X.-G., LUN Z.-R. (2006) Doubts about Trypanosoma equiperdum strains classed as Trypanosoma brucei or Trypanosoma evansi. Trends in Parasitology 22, 55- 56.
LUKEŠ J., PARIS Z., REGMI S., BREITLING R., MUREEV S., KUSHNIR S., PYATKOV K., JIRKŮ M., ALEXANDROV K.A. (2006) Translational initiation in Leishmania tarentolae and Phytomonas serpens (Kinetoplastida) is strongly influenced by pre-ATG triplet and its 5‘ sequence context. Molecular and Biochemical Parasitology 148, 125- 132.
MAURICIO I.L., YEO M., BAGHAEI M., DOTO D., SILK R., PRATLONG F., ZEMANOVÁ E., DEDET J.-P., LUKEŠ J., MILES M.A. (2006) Towards multi locus sequence typing in the Leishmania donovani complex: resolving genotypes and haplotypes for five polymorphic metabolit enzymes (ASAT, GP1, NH1, NH2, PGD). International Journal for Parasitology 36, 757- 769.
SCHUMACHER M.A., KARAMOOZ E., ZÍKOVÁ A., TRANTÍREK L., LUKEŠ J. (2006) Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism. Cell 126, 701- 711.
SIMPSON A.G.B., STEVENS J.R., LUKEŠ J. (2006) The evolution and diversity of kinetoplastid flagellates. Trends in Parasitology 22, 168- 174.
ŠMÍD O., HORÁKOVÁ E., VILÍMOVÁ V., HRDÝ I., CAMMACK R., HORVÁTH A., LUKEŠ J., TACHEZY J. (2006) Knock-downs of mitochondrial iron-sulfur cluster assembly proteins IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei. Journal of Biological Chemistry 281, 28679- 28686.
VÁVRA J., HORÁK A., MODRÝ D., LUKEŠ J., KOUDELA B. (2006) Trachipleistophora extenrec, n. sp., a new microsporidian (Fungi: Microsporidia) infecting mammals. Journal of Eukaryotic Microbiology 53, 464- 476.
WIJOVÁ M., MORAVEC F., HORÁK A., LUKEŠ J. (2006) Evolutionary relationships of Spirurina (Nematoda: Chromadorea: Rhabditida) with special emphasis on dracunculoid nematodes inferred from SSU rRNA gene sequences. International Journal for Parasitology 36, 1067- 1075.
YURCHENKO V., LUKEŠ J., XU X., MASLOV D.A. (2006) An integrated morphological and molecular approach to a new species description in the Trypanosomatidae: the case of Leptomonas podlipaevi n. sp., a parasite of Boisea rubrolineata (Hemiptera: Rhopalidae). Journal of Eukaryotic Microbiology 53, 103- 111.
YURCHENKO V.A., LUKEŠ J., JIRKŮ M., ZELEDÓN R., MASLOV D.A. (2006) Leptomonas costaricensis sp. n. (Kinetoplastea: Trypanosomatidae), a member of the novel phylogenetic group of insect trypanosomatids closely related to the genus Leishmania. Parasitology 133, 537- 546.

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