Projects

... / Research Areas / Bioorganic & Medicinal Chemistry / Michal Hocek / Projects

Development of novel methodologies for the synthesis of modified nucleobases and nucleosides

Medicinal chemistry of analogues of nucleobases and nucleosides

Desing and synthesis of modified nucleosides and base-pairs for studying of polymerase specificity and selectivity and for extension of the genetic alphabet

Construction of functionalized nucleic acids

Design and synthesis of modified nucleosides and oligonucleotides for applications in bioanalysis