Fyziologický ústav

Department of Protein Structures

List of publications in journals covered by Science Citation Index.

Authors of the department are red marked.
Authors of the Institute of Physiology are underlined.
Updated 2.4.2009

2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993

2008

1.
Grycova L. - Lansky Z. - Friedlova E. - Obsilova V. - Janouskova H. - Obsil T. - Teisinger J.
Ionic interactions are essential for TRPV1 C-terminus binding to calmodulin.
Biochemical and Biophysical Research Communications, 375(4), 680-683, 2008
IF = 2,749(07)

2.
Obsilova V. - Nedbalkova E. - Silhan J. - Boura E. - Herman P. - Vecer J. - Sulc M. - Teisinger J. - Dyda F. - Obsil T.
The 14-3-3 Protein Affects the Conformation of the Regulatory Domain of Human Tyrosine Hydroxylase.
Biochemistry, 47(6), 1768-1777, 2008
IF = 3,368(07)

3.
Mazna P. - Grycova L. - Balik A. - Zemkova H. - Friedlova E. - Obsilova V. - Obsil T. - Teisinger J.
The role of proline residues in the structure and function of human MT2 melatonin receptor.
Journal of Pineal Research, 45(4), 361-372, 2008
IF = 4,098(07)

4.
Obsil T. - Obsilova V.
Structure/function relationships underlying regulation of FOXO transcription factors.
Oncogene, 27(16), 2263-2275, 2008
IF = 6,44(07)

5.
Jelinkova I. - Vavra V. - Jindrichova M. - Obsil T. - Zemkova H.W. - Zemkova H. - Stojilkovic S. S.
Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin.
Pflugers Archiv, 465(5), 939-950, 2008
IF = 3,842(07)

6.
Drastichova Z. - Bourova L. - Lisy V. - Hejnova L. - Rudajev V. - Stohr J. - Durchankova D. - Ostasov P. - Teisinger J. - Soukup T. - Novotny J. - Svoboda P.
Subcellular redistribution of trimeric G-proteins – potential mechanism of desensitization of hormone response: internalisation, solubilization, down-regulation.
Physiological Research, 57, S1-S10, 2008
IF = 1,505(07)

2007

1.
Grycova L. - Lansky Z. - Friedlova E. - Vlachova V. - Kubala M. - Obsilova V. - Obsil T. - Teisinger J.
ATP binding site on the C-terminus of the vanilloid.
Archives of Biochemistry and Biophysics, 465(2), 389-398, 2007
IF = 2,578(07)

2.
Boura E. - Silhan J. - Herman P. - Vecer J. - Teisinger J. - Obsilova V. - Obsil T.
Both the N-terminal Loop and Wing W2 of the Forkhead Domain of Transcription Factor Foxo4 Are Important for DNA Binding.
Journal of Biological Chemistry, 282(11), 8265-8275, 2007
IF = 5,581(07)

3.
Benedikt J. - Teisinger J. - Vyklicky ml. L. - Vlachova V.
Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate.
Journal of Neurochemistry, 100(1), 211-224, 2007
IF = 4,451(07)

4.
Zemkova H. - Yan Z. - Liang Z. - Jelinkova I. - Tomic M. - Stojilkovic S. S.
Role of aromatic and charged ectodomain residues in the P2X4 receptor functions.
Journal of Neurochemistry, 102(4), 1139-1150, 2007
IF = 4,451(07)

5.
Susankova K. - Ettrich R. - Vyklicky st. L. - Teisinger J. - Vlachova V.
Contribution of the putative inner-pore region to the gating of the Transient Receptor Potential Vanilloid Subtype 1 Channel (TRPV1).
Journal of Neuroscience, 27(28), 7578-7585, 2007
IF = 7,49(07)

6.
Novakova-Tousova K. - Vyklicky st. L. - Susankova K. - Benedikt J. - Samad A. - Teisinger J. - Vlachova V.
Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization.
Neuroscience, 149(1), 144-154, 2007
IF = 3,352(07)

2006

1.
Jelinkova I. - Yan Z. - Liang Z. - Moonat S. - Teisinger J. - Stojilkovic S. S. - Zemkova H.
Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation.
Biochemical and Biophysical Research Communications, 349(2), 619-625, 2006
IF = 2,855(06)

2.
Susankova K. - Tousova K. - Vyklicky st. L. - Teisinger J. - Vlachova V.
Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current.
Molecular Pharmacology, 70(1), 383-394, 2006
IF = 4,469(06)

2005

1.
Mazna P. - Berka K. - Jelinkova I. - Balik A. - Svoboda P. - Obsilova V. - Obsil T. - Teisinger J.
Ligand binding to the human MT2 melatonin receptor: The role of residues in transmembrane domains 3, 6, and 7.
Biochemical and Biophysical Research Communications, 332(3), 726-734, 2005
IF = 3(05)

2.
Obsilova V. - Vecer J. - Herman P. - Pabianova A. - Sulc M. - Teisinger J. - Boura E. - Obsil T.
14-3-3 protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.
Biochemistry, 44(34), 11608-11617, 2005
IF = 3,848(05)

2004

1.
Janata J. - Hola K. - Kubala M. - Gakh O. - Parkhomenko N. - Matuskova A. - Kutejova E. - Amler E.
Substrate evokes translocation of both domains in the mitochondrial processing peptidase alpha-subunit during which the C-terminus acts as a stabilizing element.
Biochemical and Biophysical Research Communications, 316(1), 211-217, 2004
IF = 2,904(04)

2.
Lansky Z. - Kubala M. - Ettrich R. - Kuty M. - Plasek J. - Teisinger J. - Schoner W. - Amler E.
The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.
Biochemistry, 43(26), 8303-8311, 2004
IF = 4,008(04)

3.
Krumscheid R. - Ettrich R. - Sovova Z. - Susankova K. - Lansky Z. - Hofbauerova K. - Linnertz H. - Teisinger J. - Amler E. - Schoner W.
The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site.
European Journal of Biochemistry, 271(19), 3923-3936, 2004
IF = 3,26(04)

4.
Konopasek I. - Vecer J. - Strzalka K. - Amler E.
Short-lived fluorescence component of DPH reports on lipid-water interface of biological membranes.
Chemistry and Physics of Lipids, 130(2), 135-144, 2004
IF = 1,971(04)

5.
Obsilova V. - Herman P. - Vecer J. - Sulc M. - Teisinger J. - Obsil T.
14-3-3zeta C-terminal stretch changes its conformation upon ligand binding and phosphorylation at Thr232.
Journal of Biological Chemistry, 279(6), 4531-4540, 2004
IF = 6,355(04)

6.
Silhan J. - Obsilova V. - Vecer J. - Herman P. - Sulc M. - Teisinger J. - Obsil T.
14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding.
Journal of Biological Chemistry, 279(47), 49113-49119, 2004
IF = 6,355(04)

7.
Mazna P. - Obsilova V. - Jelinkova I. - Balik A. - Berka K. - Sovova Z. - Ettrich R. - Svoboda P. - Obsil T. - Teisinger J.
Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.
Journal of Neurochemistry, 91(4), 836-842, 2004
IF = 4,824(04)

8.
Tousova K. - Susankova K. - Teisinger J. - Vyklicky st. L. - Vlachova V.
Oxidizing reagent copper-o-phenanthroline is an open channel blocker of the vanilloid receptor TRPV1.
Neuropharmacology, 47(2), 273-285, 2004
IF = 3,734(04)

9.
Kubala M. - Obsil T. - Obsilova V. - Lansky Z. - Amler E.
Protein modeling combined with spectroscopi techniques: an attractive quick alternative to obtain structural information.
Physiological Research, 53(Suppl. 1), S187-S197, 2004
IF = 1,14(04)

10.
Svoboda P. - Teisinger J. - Novotny J. - Bourova L. - Drmota T. - Hejnova L. - Moravcova Z. - Lisy V. - Rudajev V. - Stohr J. - Vokurkova A. - Svandova I. - Durchankova D.
Biochemistry of transmembrane signaling mediated by trimeric G proteins.
Physiological Research, 53(Suppl. 1), S141-S152, 2004
IF = 1,14(04)

2003

1.
Krumscheid R. - Susankova K. - Ettrich R. - Teisinger J. - Amler E. - Schoner W.
Localization of catalytic active sites in the large cytoplasmic domain of Na+/K+-ATPase.
Annals of the New York Academy of Sciences, 986(-), 242-244, 2003
IF = 1,892(03)

2.
Hofbauerova K. - Kopecky ml. V. - Ettrich R. - Kubala M. - Teisinger J. - Amler E.
ATP-binding is stabilized by a stacking interaction within the binding site of Na(+)/K(+)-ATPase.
Biochemical and Biophysical Research Communications, 306(2), 416-420, 2003
IF = 2,836(03)

3.
Kubala M. - Teisinger J. - Ettrich R. - Hofbauerova K. - Kopecky ml. V. - Baumruk V. - Krumscheid R. - Plasek J. - Schoner W. - Amler E.
Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.
Biochemistry, 42(21), 6446-6452, 2003
IF = 3,922(03)

4.
Hofbauerova K. - Kopecky ml. V. - Sykora J. - Karpenko V.
Thermal stability of the human blood serum acid alpha(1)-glycoprotein in acidic media.
Biophysical Chemistry, 103(1), 25-33, 2003
IF = 1,728(03)

5.
Kubala M. - Plasek J. - Amler E.
Limitations in linearized analyses of binding equilibria: binding of TNP-ATP to the H(4)-H(5) loop of Na/K-ATPase.
European Biophysics Journal, 32(4), 363-369, 2003
IF = 1,769(03)

6.
Vlachova V. - Teisinger J. - Susankova K. - Lyfenko A. - Ettrich R. - Vyklicky st. L.
Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1.
Journal of Neuroscience, 23(4), 1340-1350, 2003
IF = 8,306(03)

2002

1.
Kubala M. - Hofbauerova K. - Ettrich R. - Kopecky ml. V. - Krumscheid R. - Plasek J. - Teisinger J. - Schoner W. - Amler E.
Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase.
Biochemical and Biophysical Research Communications, 297(1), 154-159, 2002
IF = 2,935(02)

2.
Hofbauerova K. - Kopecky ml. V. - Ettrich R. - Ettrichova O. - Amler E.
Secondary and tertiary structure of nucleotide-binding domain of alpha subunit of Na+/K+-ATPase.
Biopolymers, 67(4-5), 242-246, 2002
IF = 2,372(02)

3.
Abdrachmanova G. - Teisinger J. - Vyklicky ml. L.
Axotomy-induced changes in the properties of NMDA receptor channels in rat spinal cord motoneurons.
Journal of Physiology, 538(1), 53-63, 2002
IF = 4,65(02)

4.
Vyklicky st. L. - Lyfenko A. - Susankova K. - Teisinger J. - Vlachova V.
Reducing agent dithiothreitol facilitates activity of the capsaicin receptor VR-1.
Neuroscience, 111(3), 435-441, 2002
IF = 3,457(02)

2001

1.
Gakh O. - Obsil T. - Adamec J. - Spizek J. - Amler E. - Janata J. - Kalousek F.
Substrate binding changes conformation of the alpha-, but not the beta-subunit of mitochondrial processing peptidase.
Archives of Biochemistry and Biophysics, 385(2), 392-396, 2001
IF = 2,476(01)

2.
Ettrich R. - Melichercik M. - Teisinger J. - Ettrichova O. - Krumscheid R. - Hofbauerova K. - Kvasnicka P. - Schoner W. - Amler E.
Three-dimensional structure of the large cytoplasmic H-4-H-5 loop of Na(+)/K(+)-ATPase deduced by restraint-based comparative modeling shows only one ATP binding site.
Journal of Molecular Modeling, 7(6), 184-192, 2001
IF = 1,011(01)

2000

1.
Tanfani F. - Linnertz H. - Obsil T. - Krumscheid R. - Urbanova P. - Jelinek O. - Mazzanti L. - Bertoli E. - Schoner W. - Amler E.
Effects of fluorenscent pseudo-ATP and ATP-metal analogs on secondary structure of Na+/K+-ATPase.
Biochimica et Biophysica Acta-Bioenergetics, 1457, 94-102, 2000
IF = 6,346(00)

2.
Abdrachmanova G. - Teisinger J. - Vlachova V. - Vyklicky ml. L.
Molecular and functional properties of synaptically activated NMDA receptors in neonatal motoneurons in rat spinal cord slices.
European Journal of Neuroscience, 12, 955-963, 2000
IF = 3,862(00)

1999

1.
Linnertz H. - Lanz E. - Gregor M. - Antolovic R. - Krumscheid R. - Obsil T. - Slavik J. - Kovarik Z. - Schoner W. - Amler E.
Microenvironment of the high affinity ATP-binding site of Na+/K+ -ATPase is slightly acidic.
Biochemical and Biophysical Research Communications, 254, 215-221, 1999
IF = 3,161(99)

2.
Obsil T. - Amler E. - Obsilova V. - Pavlicek Z.
Effect of aminophospholipid glycation on order parameter and hydration of phospholipid bilayer.
Biophysical Chemistry, 80, 165-177, 1999
IF = 1,498(99)

3.
Obsil T. - Hofbauerova K. - Amler E. - Teisinger J.
Different cation binding to the I domains of alpha1 and alpha2 integrins: implication of the binding site structure.
FEBS Letters, 457(3), 311-315, 1999
IF = 3,72(99)

4.
Thoenges D. - Amler E. - Eckert T. - Schoner W.
Tight binding of bulky fluorescent derivatives of adenosine to the low affinity E2ATP site leads to inhibition of Na+/K+ -ATPase.
Journal of Biological Chemistry, 274(4), 1971-1978, 1999
IF = 7,666(99)

1998

1.
Obsil T. - Amler E. - Pavlicek Z.
Aminophospholipid glycation causes lipid bilayer structure alterations and inhibition of membrane-bound Na+/K+ -ATPase.
Collection of Czechoslovak Chemical Communications, 63, 1060-1073, 1998
IF = 0,546(98)

2.
Linnertz H. - Miksik I. - Kvasnicka P. - Bertoli E. - Mazzanti L. - Schoner W. - Amler E.
Binding of pyrene isothiocyanate to the E1ATP site makes the H4-H5 cytoplamic loop of Na+/K+ -ATPase rigid.
European Journal of Biochemistry, 251(2), 522-527, 1998
IF = 3,249(98)

3.
Linnertz H. - Kost H. - Obsil T. - Kotyk A. - Amler E. - Schoner W.
Erythrosin 5'-isothiocyanate labels Cys 549 as part ot the low-affinity ATP binding site of Na+/K+ -ATPase.
FEBS Letters, 441(1), 103-105, 1998
IF = 3,581(98)

4.
Obsil T. - Merola F. - Lewit-Bentley A. - Amler E.
The isolated H4-H5 cytoplasmic loop of Na,K-ATPase overexpressed in Escherichia coli retains its ability to bind ATP.
FEBS Letters, 426, 297-300, 1998
IF = 3,581(98)

5.
Konopasek I. - Kvasnicka P. - Herman P. - Linnertz H. - Obsil T. - Vecer J. - Svobodova J. - Strzalka K. - Mazzanti L. - Amler E.
The origin of the diphenylhexatriene short lifetime component in membranes and solvents.
Chemical Physics Letters, 293, 429-435, 1998
IF = 2,257(98)

6.
Linnertz H. - Urbanova P. - Obsil T. - Herman P. - Amler E. - Schoner W.
Molecular Distance Measurements reveal an (alpha beta)2 dimeric structure of Na+/K+ -ATPase.
Journal of Biological Chemistry, 273(44), 28813-28821, 1998
IF = 7,199(98)

1997

1.
Brinkmann K. - Linnertz H. - Amler E. - Lanz E. - Herman P. - Schoner W.
Fluoresceinyl-ethylenediamine-ouabain detects an acidic environment in the cardiac glycoside binding site of Na+/K+ -ATPase.
European Journal of Biochemistry, 249, 301-308, 1997
IF = 3,136(97)

2.
Linnertz H. - Urbanova P. - Amler E.
Quenching of 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole-modified Na+/K+ -ATPase reveals a higher accessibility of the low-affinity ATP-binding site.
FEBS Letters, 419(2-3), 227-230, 1997
IF = 3,504(97)

3.
Amler E.
Can insulin-dependent diabetes mellitus be understood at the molecular level through Na+/K+ -adenosine triphosphatase ?
Journal of Laboratory and Clinical Medicine, 130(4), 352-353, 1997
IF = 1,808(97)

4.
Sabala P. - Amler E. - Baranska J.
Intracellular Ca2+ signals induced by ATP and thapsigargin in glioma C6 cells. Calcium pools sensitive to inositol 1,4,5-trisphosphate and thapsigargin.
Neurochemistry International, 31(1), 55-64, 1997
IF = 1,705(97)

5.
Amler E. - Staffolani R. - Baranska J. - Obsil T. - Urbanova P. - Bertoli E. - Mazzanti L.
Oligosaccharide organization on the beta-subunits of pig kidney Na+/K+ -ATPase.
Physiological Research, 46(6), 407-417, 1997
IF = 0,807(97)

6.
Linnertz H. - Lastres-Becker I. - Krumscheid R. - Amler E. - Thoenges D. - Schoner W.
2`(3`)-O-[N- [2- [3- [-fluoresceinyl] thioureido] ethyl] carbamoyl] adenosine 5`-triphosphate and its Cr[H2O]4 and Co[NH3]4 complex derivatives are new fluorescent tools for labelling ATP binding sites of Na+/K+ -ATPase.
Physiological Research, 46(5), 345-349, 1997
IF = 0,807(97)

1996

1.
Amler E. - Abbot A. - Malak H. - Lakowicz J. - Ball jr. W.J.
The carbohydrate moieties of the beta-subunit of Na+/K+ -ATPase: Their lateral motions and proximity to the cardiac glycoside site.
Biophysical Journal, 7(1), 182-193, 1996
IF = 4,713(96)

2.
Opekarova M. - Urbanova P. - Konopasek I. - Kvasnicka P. - Strzalka K. - Siegler K. - Amler E.
Possible nystatin-protein interaction in yeast plasma membrane vesicles in the presence of ergosterol. A Forster energy transfer study.
FEBS Letters, 386(2,3), 181-184, 1996
IF = 3,75(96)

1995

1.
Konopasek I. - Kvasnicka P. - Amler E. - Kotyk A. - Curatola G.
The transmembrane gradient of the dielectric constant influences the DPH lifetime distribution.
FEBS Letters, 374, 338-340, 1995
IF = 3,842(95)

2.
Obsil T. - Amler E. - Kotyk A. - Pavlicek Z.
Enzymically generated electron-excited speciels Increase the membrane order parameter without changing the rotational relaxation time of TMA-DPH.
General Physiology and Biophysics, 14(5), 393-403, 1995
IF = 0,42(95)

3.
Stankovicova T. - Zemkova H. - Breier A. - Amler E. - Burkhard M. - Vyskocil F.
The effects of calsium and calcium channel blockers on sodium pump.
Pflugers Archiv-European Journal of Physiology, 429(5), 716-721, 1995
IF = 2,646(95)

4.
Kotyk A. - Amler E.
Na, K-adenosinetriphosphatase: The paradigm of a membrane transport protein.
Physiological Research, 44(5), 261-274, 1995
IF = 0,588(95)

1994

1.
Amler E. - Cester N. - Salvolini E. - Staffolani R. - Burkhard M. - Mazzanti L.
Human hypertensive placenta contains and increased amount of Na, K-ATPase with higher affinity for cardiac glycosides.
Cell Biology International, 18(7), 723-727, 1994
IF = 1,042(94)

2.
Kosar E. - Teisinger J. - Vyskocil F. - Vanecek J.
Chemical modification of melatonin receptors in chicken brain.
Journal of Neurochemistry, 63(2), 662-670, 1994
IF = 4,525(94)

3.
Kozak U.C. - Kopecky J. - Teisinger J. - Enerback S. - Boyer B. - Kozak L.P.
An Upstream Enhancer Regulation Brown-Fat-Specific Expression of the Mitochondrial Uncoupling Protein Gene.
Molecular and Cellular Biology, 14(1), 59-67, 1994
IF = 10,195(94)

4.
Amler E. - Cester N. - Magnanelli R. - Mazzanti L. - Kotyk A. - Romanini C.
Na, K-ATPase from placenta of women with pregnancy - induced hypertension exhibits and increased affinity for cardiac glycosides
Physiological Research, 43(1), 33-36, 1994
IF = 0,318(94)

1993