Staff

Name Holý Petr
Position Scientist

Petr Holý

Petr Holý, Ph.D.

Scientist, Project Leader

Chemistry of Functional Molecules Research Group
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

Phone: (+420) 220 183 382 (465)
Fax: (+420) 220 183 133
E-mail: petrholy@uochb.cas.cz

 
Education
1979 Ph.D. (CSc.) in Organic Chemistry, under supervision of Prof. M. Janda, Institute of Chemical Technology, Prague.
1973 M.Sc. (Ing.) in Organic Chemistry, under supervision of Prof. M. Janda, Institute of Chemical Technology, Prague.
 
Experience
1989-1990 Postdoctoral fellow with Prof. W. Simon, ETH Zürich, Switzerland.
 
Appointments
Currently Senior scientist and a project leader in the Chemistry of Functional Molecules Research Group, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
1994-2006 Head of the Supramolecular group at Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague.
Since 1986 He has joined the Department of Organic Chemistry, Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague.
1979-1985 Research worker with Prof. Z. Vodráľka at the Biochemical Department of the Institute of Hematology and Blood Transfusion, Prague.
 
Awards and organizations
Since 2002 Member of the Editorial Board of the Czech national chemical journal "Chemické listy".
 
Research interest
Synthetic organic chemistry, supramolecular chemistry, crystal engineering.
 
 
 
Selected papers
 

Rybáčková, M.; Bělohradský, M.; Holý, P.; Pohl, R.; Dekoj, V.; Závada, J.
Synthesis 2007, 1554-1558.
Synthesis of Highly Symmetrical Triptycene Tetra- and Hexacarboxylates.

Rybáček, J.; Rybáčková, M.; Høj, M.; Bělohradský, M.; Holý, P.; Kilså, K.; Nielsen M.B.
Tetrahedron 2007, 63, 8840-8854.
Tetrathiafulvalene-Functionalized Triptycenes: Synthetic Protocols and Elucidation of Intramolecular Coulomb Repulsions in the Oxidized Species.

Holý, P.; Havlík, M.; Tichý, M.; Závada, J.; Císařová, I.
Collect. Czech. Chem. Commun. 2006, 71, 138-154.
Synthesis ans self-assembly of 9,9´-spirobifluorene-2,2´,7,7´-tetracarboxylic acid and its tetraamide. Non-catenated formation of achiral grid layers with large chiral pores.

Holý, P.; Kováč, M.; Tichý, M.; Závada, J.; Buděšínský, M.; Císařová, I.
Tetrahedron: Asymmetry 2005, 16, 2031-2038.
Interpenetrating chiral 2D grid nets: hetero- versus homochiral 3D polycatenation in the crystal self-assembly of (RS)- and (R)-1,1´-binaphthalene-2,2´,6,6´-tetracarboxylic acids.

Holý, P.; Sehnal P., Tichý, M.; Závada, J.; Císařová, I.
Tetrahedron: Asymmetry 2004, 15, 3805-3810.
Crystal structure of 1,1´-biphenyl-2,2´,3,3´-tetracarboxylic and 1,1´-biphenyl-2,2´,3,3´,5,5´,6,6´-octacarboxylic acids: solid state chiralization and dissociation.

Bělohradský, M.; Buděšínský, M.; Císařová, I.; Dekoj, V.; Holý, P.; Závada, J.
Tetrahedron 2003, 59, 7751-7760.
Macrocyclic cis- and trans- Bis(α-amino Acids) and their Intraannular Cu(II) Complexes. Conformational in-out Dichotomy and Crystal Packing.

Holý, P.; Sehnal P., Tichý, M.; Závada, J.; Císařová, I.
Tetrahedron: Asymmetry 2003, 14, 245-253.
Self-assembly of chiral hydrogen-bonded grid layers from terephthalic Siamese twins.

Bělohradský, M.; Císařová, I.; Holý, P.; Pastor, J.; Závada, J.
Tetrahedron 2002, 58, 8811-8823.
α-Amino Acids and Dioxopiperazines Crowned at the α-Carbons with Polyether Macrorings. Synthesis, Complexation and Self-Assembling Properties.

Sehnal, P.; Holý, P.; Tichý, M.; Závada, J.; Císařová, I.
Collect. Czech. Chem. Commun. 2002, 67, 1236-1246.
Synthesis and self-assembling properties of the free base and the 1:1 silver(I)triflate complex.

Holý, P.; Závada, J.; Císařová, I.; Podlaha, J.
Tetrahedron: Asymmetry 2001, 12, 3035-3045.
Self-assembly of enantiopure and racemic 2,2´,6,6´-tetrasubstituted biaryl tectons into hydrogen bonded chiral squares and infinite chiral square layers.

Tichý, M.; Holý, P.; Závada, J.; Císařová, I.; Podlaha, J.
Tetrahedron: Asymmetry 2001, 12, 2295-2300.
Helix-forming self-assembly of enantiopure 2,2´-dimethylbiphenyl-6,6´-dipropiolic acid and amide organized by hydrogen bonds.

Holý, P.; Závada, J.; Zezula, J.; Císařová, I.; Podlaha, J.
Collect. Czech. Chem. Commun. 2001, 66, 820-832.
Formation of infinite grids with chiral square compartments by self-assembly of achiral 1,1´-biphenyl-2,2´,6,6´-tetracarboxylic acids. Effect of 4,4´-substitution on the grid stacking.

Holý, P.; Podlaha, J.; Císařová, I.; Závada, J.
Collect. Czech. Chem. Commun. 2001, 66, 947-958.
Self-assembly of 1,1´-biphenyl-2,2´,6,6´-tetracarboxamides. Effect of substitution at the amidic nitrogen.

Holý, P.; Závada, J.;, Podlaha, J.; Císařová, I.
Angew. Chem. Int. Ed., 1999, 38, 381-383.
Self-assembly of 1,1´-biphenyl-2,2´,6,6´-tetracarboxylic acid: Formation of an achiral grid with chiral compartments.

Tichý, M.; Ridvan, L.; Holý, P.; Závada, J.; Císařová, I.; Podlaha, J.
Tetrahedron: Asymmetry 1998, 9, 227-234.
Axially chiral dilactams. Synthesis, racemization barriers and crystal structures.

Holý, P.; Havránek, M.; Pánková, M.; Ridvan, L.; Závada, J.
Tetrahedron 1997, 53, 8195-8210.
Solvent and leaving group effects on the mono- vs. dialkylation of alkali salts of diethyl malonate with 1,2-bis-, 1,2,4,5-tetrakis- and 1,2,3,4,5,6-hexakis(halomethyl)benzenes. A new insight into selectivity control of malonester synthesis.

Bělohradský, M.; Buděšínský, M.; Günterová, J.; Hodačová, J.; Holý, P.; Závada, J.; Císařová, J.; Podlaha, J.
Tetrahedron 1996, 52, 11013-11024
C-C coupling reaction of 1,5-dibromo-2,6-dihydroxynaphthalene with alkali 2-naphthoxide. Opposite effects of counterion coordination and hydrogen bonding on stereoselectivity in the formation of cis- and trans-1,1':5',1''-ternaphthyls.