2004

Turek P., Kotora M., Tislerova I., Hocek M., Votruba I., Císařová I.:
Cocyclotrimerization of 6-alkynylpurines with diynes as a novel approach to biologically active 6-arylpurines.
Journal of Organic Chemistry 26 (69): 9224-9233, 2004.

Fernandez-Botello A., Holý A., Moreno V., Sigel H.:
Intramolecular stacking interactions in ternary copper(II) complexes formed by a heteroaromatic amine and 9-[2-(2-phosphonoethoxy)ethyl]adenine, a relative of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine.
Journal of Inorganic Biochemistry 12 (98): 2114-2124, 2004.

Gomez-Coca R.B., Kapinos L.E., Holý A., Vilaplana R.A., Gonzalez-Vilchez F., Sigel H.:
Quantification of isomeric equilibria formed by metal ion complexes of 8-[2-(phosphonomethoxy)ethyl]-8-azaadenine (8,8aPMEA) and 9-[2- (phosphonomethoxy)ethyl]-8-azaadenine (9,8aPMEA). Derivatives of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy) ethyl]adenine (PMEA).
Journal of Biological Inorganic Chemistry 8 (9): 961-972, 2004.

Zídek Z., Kmoničková E., Holý A.:
Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues.
European Journal of Pharmacology 1-3 (501): 79-86, 2004.

Krečmerová M., Masojídková M., Holý A.:
Synthesis of N9- and N7-[2-hydroxy-3- (phosphonomethoxy)-propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds.
Collection of Czechoslovak Chemical Communications 10 (69): 1889-1913, 2004.

Naus P., Votruba I., Hocek M.:
Covalent analogues of DNA base-pairs and triplets VII.+ synthesis and cytostatic activity of bis(purin-6-yl)acetylene and -diacetylene nucleosides.
Collection of Czechoslovak Chemical Communications 10 (69): 1955-1970, 2004.

Bzowska A., Koellner G., Wielgus-Kutrowska B., Stroh A., Raszewski G., Holý A., Steiner T., Frank J.:
Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: Important implications for the mechanism of catalysis.
Journal of Molecular Biology 3 (342): 1015-1032, 2004.

Šilhár P., Pohl R., Votruba I., Hocek M.:
Facile and efficient synthesis of 6-(hydroxymethyl)purines.
Organic Letters 19 (6): 3225-3228, 2004.

Otmar M., Masojídková M., Votruba I., Holý A.:
Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9- deazapurine and related compounds.
Bioorganic and Medicinal Chemistry 12 (12): 3187-3195, 2004.

Hocková D., Holý A., Masojídková M., Andrei G., Snoeck R., De Clercq E., Balzarini J.:
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2- (phosphonomethoxy)ethoxy]pyrimidine and related compounds.
Bioorganic and Medicinal Chemistry 12 (12): 3197-3202, 2004.

Hocková D., Holý A., Masojídková M., Votruba I.:
An efficient synthesis of cytostatic mono and bis-alkynylpyrimidine derivatives by the Sonogashira cross-coupling reactions of 2,4-diamino-6- iodopyrimidine and 2-amino-4,6-dichloropyrimidine.
Tetrahedron 23 (60): 4983-4987, 2004.

Hocek M., Štěpnička P., Ludvik J., Císařová I., Votruba I., Reha D., Hobza P.:
Ferrocene-Modified Purines as Potential Electrochemical Markers: Synthesis, Crystal Structures, Electrochemistry and Cytostatic Activity of (Ferrocenylethynyl)- and (Ferrocenylethyl)purines.
Chemistry - A European Journal 8 (10): 2058-2066, 2004.

Šála M., Hřebabecký H., Masojídková M., Holý A.:
Synthesis of racemic 2-hydroxy-4- and 2-hydroxy-5-(hydroxymethyl) cyclohexane pyrimidine C-Nucleoside analogues.
Collection of Czechoslovak Chemical Communications 4 (69): 918-932, 2004.

Pískala A., Hanna N.B., Masojídková M., Fiedler P., Votruba I.:
Synthesis of N4-amino and N4-hydroxy derivatives of 5-azacytidine. A facile rearrangement of the N4-amino derivative to 5-(3-D-ribofuranosylureido)-1H-1,2,4-triazole.
Collection of Czechoslovak Chemical Communications 4 (69): 905-917, 2004.

Buchta V., Pour M., Kubanová P., Silva L., Votruba I., Vopršalová M., Schiller R., Fakova H., Spulak M.:
In Vitro Activities of 3-(Halogenated Phenyl)-5-Acyloxymethyl-2,5-Dihydrofuran-2-ones against Common and Emerging Yeasts and Molds.
Antimicrobial Agents and Chemotherapy 3 (48): 873-878, 2004.

Hřebabecký H., Masojídková M., Holý A.:
Synthesis of purine nucleoside analogues derived from carbocyclic 5-C-(hydroxymethyl)hexopyranoses.
Collection of Czechoslovak Chemical Communications 2 (69): 435-452, 2004.

Balzarini J., Pannecouque C., Naesens L., Andrei G., Snoeck R., De Clercq E., Hocková D., Holý A.:
6-[2-Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity.
Nucleosides, Nucleotides and Nucleic Acids 8-9 (23): 1321-1327, 2004.

Birkus G., Rejman D., Otmar M., Votruba I., Rosenberg I., Holý A.:
The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases α, β and ε.
Antiviral Chemistry and Chemotherapy 1 (15): 23-33, 2004.