09.1.2010 - Journal article: Journal of Neurophysiology

The Role of The TRPV1 Endogenous Agonist N-Oleoyldopamine in Modulation of Nociceptive Signaling at the Spinal Cord Level.

OLDA application in acute spinal cord slices leads to significant increase of AMPA mediated mEPSC frequency in high concentration. After PKC activation or under pathological conditions only low concentration is needed. Presynaptic spinal cord TRPV1 receptors have a significant modulatory role in nociceptive signalling and may be activated by low concentrations of endogenous agonists like OLDA under pathological conditions.

Špicarová D, Paleček J.: The Role of The TRPV1 Endogenous Agonist N-Oleoyldopamine in Modulation of Nociceptive Signaling at the Spinal Cord Level. Journal of Neurophysiology 2009; 102: 234-243.IF=3.648

 

Author: dianaspicarova@biomed.cas.cz

22.3.2010 - 25th International Symposium on MicroScale Bioseparations Prague, March 21-25, 2010
Welcome to the 25th International Symposium on MicroScale Bioseparations Prague, March 21-25, 2010

13.1.2010 - Journal article: Endocrinology

Chronic Intermittent Hypoxia Induces 11Beta-Hydroxysteroid Dehydrogenase in Rat Heart.

12.1.2010 - Journal article: Epilepsia
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11.1.2010 - Journal article: International Journal of Biochemistry and Cell Biology
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10.1.2010 - Journal article: Chronobiology International
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08.1.2010 - Journal article: Proceedings of the National Academy of Sciences of the USA
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02.11.2009 - Seminar
POTASSIUM AND SODIUM HOMEOSTASIS IN YEASTS

11.6.2009 - Laser microdissection system Leica LMD600
Laser microdissection system Leica LMD600 was installed in the Institute of Physiology.

03.6.2009 - FLIM seminar
June 3, 2009: Seminar on Fluorescence Lifetime Imaging Techniques at the Institute of Physiology

28.5.2009 -  INVITATION
8th EUROPEAN FORUM FOR SCIENCE AND TECHNOLOGY

21.5.2009 - Special Award for Dr. Pavel Flachs
Dr. P. Flachs was awarded with Otto Wichterle Premium

18.2.2009 - The Honorary Medal of J. E. Purkynje for Dr. Jaroslav Kunes
The Honorary Medal of J. E. Purkynje for Dr. Jaroslav Kunes