Journal article: Endocrinology

Chronic Intermittent Hypoxia Induces 11Beta-Hydroxysteroid Dehydrogenase in Rat Heart.

Myocardial remodeling induced by chronic intermittent hypoxia is associated with up-regulation of cardiac 11beta-hydroxysteroid dehydrogenase type 2. Consequently, local metabolism of glucocorticoids could play a role in the cardiac hypertrophy and fibrosis.
Klusonová P, Reháková L, Borchert G, Vagnerová K, Neckár J, Ergang P, Miksík I, Kolár F, Pácha J.: Chronic Intermittent Hypoxia Induces 11Beta-Hydroxysteroid Dehydrogenase in Rat Heart. Endocrinology 2009;150:4270-4277. IF=4.945
 

Author: klusonovabiomed.cas.cz

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