Vyznamne publikace

Selected publications

Selected publications in which at least the first or corresponding author is affiliated with the Institute of Molecular Genetics

(names of all IMG employees are underlined)

2009

Mihola, O. - Trachtulec, Z. - Vlček, C. - Schimenti, J.C. - Forejt, J.
Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase.
Science, 323(5912): 373-5 (2009). PubMed

Huranova, M. - Hnilicova, J. - Fleischer, B. - Cvackova, Z. - Stanek D.
A mutation linked to retinitis pigmentosa in HPRP31 causes protein instability and impairs its interactions with spliceosomal snRNPs.
Hum Mol Genet., 18(11): 2014-23 (2009). Epub 2009 Mar 17. PubMed

Zheng, L. - Kanagaraj, R. - Mihaljevic, B. - Schwendener, S. - Sartori, A.A. - Gerrits, B. - Shevelev, I. - Janscak, P.
MRE11 complex links RECQ5 helicase to sites of DNA damage.
Nucleic Acids Res., 37(8): 2645-57 (2009). Epub 2009 Mar 6. PubMed

Lukas, J. - Mazna, P. - Valenta, T. - Doubravska, L. - Pospichalova, V. - Vojtechova, M. - Fafilek, B. - Ivanek, R. - Plachy, J. - Novak, J. - Korinek, V.
Dazap2 modulates transcription driven by the Wnt effector TCF-4.
Nucleic Acids Res., 37(9): 3007-20 (2009). Epub 2009 Mar 20. PubMed

Pajer, P. - Karafiat, V. - Pecenka, V. - Prukova, D. - Dudlova, J. - Plachy, J. - Kasparova, P. - Dvorak M.
Industasis, a promotion of tumor formation by nontumorigenic stray cells.
Cancer Res., 69(11): 4605-12 (2009). PubMed

Blazkova, J. - Trejbalova, K. - Gondois-Rey, F. - Halfon, P. - Philibert, P. - Guiguen, A. - Verdin, E. - Olive, D. - Van Lint, C. - Hejnar, J. - Hirsch, I.
CpG methylation controls reactivation of HIV from latency.
PloS Pathog., 5(8): e1000554 (2009). Epub 2009 Aug 21. PubMed

2008

Svoboda, P.
RNA silencing in mammalian oocytes and early embryos.
Curr Top Microbiol Immunol., 320:225-256 (2008). PubMed

Bartek, J. - Hodny, Z. - Lukas, J.
Cytokine loops driving senescence.
Nat Cell Biol., 10: 887-889 (2008). PubMed

Bubenik J.
Genetically modified cellular vaccines for therapy of human papilloma virus type 16 (HPV 16)-associated tumours.
Curr Cancer Drug Targets, 8: 180-186 (2008). PubMed

Stanek, D. - Pridalová-Hnilicova, J. - Novotny, I. - Huranova, M. - Blazikova, M. - Wen, X. - Sapra, A.K. - Neugebauer, K.M.
Spliceosomal small nuclear ribonucleoprotein particles repeatedly cycle through Cajal bodies.
Mol Biol Cell., 19: 2534-2543 (2008). PubMed

Kozmik, Z. - Ruzickova, J. - Jonasova, K. - Matsumoto, Y. - Vopalensky, P. - Kozmikova, I. - Strnad, H. - Kawamura, S. - Piatigorsky, J. - Paces, V. - Vlcek, C.
Assembly of the cnidarian camera-type eye from vertebrate-like components.
Proc Natl Acad Sci USA, 105(26): 8989-8993 (2008). PubMed

Sinkkonen, L. - Hugenschmidt, T. - Berninger, P. - Gaidatzis, D. - Mohn, F. - Artus-Revel, C.G. - Zavolan, M. - Svoboda, P.* - Filipowicz, W.*
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells.
Nat Struct Mol Biol., 15(3): 259-67 (2008). PubMed

Gregorová, S. - Divina, P. - Storchová, R. - Trachtulec, Z. - Fotopulosová, V. - Svenson, K.L. - Donahue, L.R. - Paigen, B. - Forejt J.
Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies.
Genome Res., 18: 509-515 (2008). PubMed

2007

Vlasakova, J. - Novakova, Z. - Rossmeislova, L. - Kahle, M. - Hozak, P. - Hodny, Z.
Histone deacetylase inhibitors suppress IFNalpha-induced up-regulation of promyelocytic leukemia protein.
Blood, 109: 1373-80 (2007). PubMed

Sojka, L. - Fučík, V. - Krásný, L. - Barvík, I. - Jonák, J.
YbxF – a protein associated with exponential phase ribosomes in Bacillus subtilis.
J. Bacteriol. 189: 4809-14 (2007). PubMed

Homolka, D. - Ivanek, R. - Capkova, J. - Jansa, P. - Forejt, J.
Chromosomal rearrangement interferes with meiotic X chromosome inactivation.
Genome Res., 17: 1431-7 (2007). PubMed

Smrz, D. - Draberova, L. - Draber, P.
Non-apoptotic phosphatidylserine externalization induced by engagement of glycosylphosphatidylinositol-anchored proteins.
J. Biol. Chem., 282: 10487-97 (2007). PubMed

Fujimura, N. - Vacik, T. - Machon, O. - Vlcek, C. - Scalabrin, S. - Speth, M. - Diep, D. - Krauss, S. - Kozmik, Z.
Wnt-mediated downregulation of Sp1 target genes by a transcriptional repressor Sp5.
J. Biol. Chem., 282 [20]: 1225-1237 (2007). PubMed

2006

Reinis M. - Simova J. - Bubenik J.
Inhibitory effects of unmethylated CpG oligodeoxynucleotides on MHC vlase I-deficient and -proficient HPV16-associated tumours.
Int. J. Cancer, 118 1836-1842 (2006). PubMed

Matoušková, M. - Blažková, J. - Pajer, P. - Pavlíček, A. - Hejnar, J.
CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues. Exp. Cell Res., 312 [7] 1011-1020 (2006). PubMed

Lipoldova, M. - Demant, P.
Genetic susceptibility to infectious disease: lessons from mouse models of leishmaniasis.
Nat. Rev. Genet., 7 [4] 294-305 (2006). PubMed

Štokrová, J. - Šloncová, E. - Sovová, V. - Kučerová, D. - Žíla, V. - Turečková, J. - Vojtěchová, M. - Korb, J. - Tuháčková Z.
Characterization of four clones derived from human adenocarcinoma cell line, HT29, and analysis of their response to sodium butyrate.
Int. J. Oncol., 28 559-565 (2006). PubMed

Heneberg, P. - Lebduška, P. - Dráberová, L. - Korb, J. - Dráber, P.
Topography of plasma membrane microdomains and its consequences for mast cell signaling.
Eur. J. Immunol., 36 2795-2806 (2006). PubMed

Koc, M. - Naďová, Z. - Kovář, J.
Sensitivity of cells to apoptosis induced by iron deprivation can be reversibly changed by iron availability.
Cell Prolif., 39 [6] 551-561 (2006). PubMed

Asahina, M. - Valenta, T. - Šilhánková, M. - Kořínek, V. - Jindra, M.:
Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad.
Dev. Cell, 11 [2] 203-211 (2006). PubMed

Valenta, T. - Lukáš, J. - Doubravská, L. - Fafílek, B. - Kořínek, V.
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.
EMBO J., 25 [11] 2326-2337 (2006). PubMed

Tedoldi, S. - Paterson, J.C. - Hansmann, M.L. - Natkunam, Y. - Ruediger, T. - Angelisová, P. - Du, M.Q. - Roberton, H. - Roncador, G. - Sanchez, L. - Pozzobon, M. - Masir, N. - Barry, R. - Pileri, S. - Mason, D.Y. - Marafioti, T. - Hořejší, V.
Transmembrane adaptor molecules: a new category of lymphoid-cell markers.
Blood, 107 213-221 (2006). PubMed

Katsetos, C.D. - Reddy, G. - Dráberová, E. - Šmejkalová, B. - Del Valle, L. - Ashraf, Q. - Tadevosyan, A. - Yelin, K. - Maraziotis, T. - Mishra, O.P. - Mörk, S. - Legido, A. - Nissanov, J. - Baas, P.W. - de Chadarévian, J.P. - Dráber, P.
Altered cellular distribution and subcellular sorting of γ-tubulin in diffuse astrocytic gliomas and human glioblastoma cell lines suggest centrosome protein amplification.
J. Neuropathol. Exp. Neurol., 65 465-477 (2006). PubMed

Sulimenko, V. - Dráberová, E. - Sulimenko, T. - Macůrek, L. - Richterová, V. - Dráber, Pe. - Dráber, P.
Regulation of microtubule formation in activated mast cells by complexes of γ-tubulin with Fyn and Syk kinases.
J. Immunol., 176 7243-7253 (2006). PubMed

Pavlíček, A. - Gentles, A.J. - Pačes, J. - Pačes, V. - Jurka, J.
Retroposition of processed pseudogenes: the impact of RNA stability and translational control.
Trends Genet, 22 [2] 69-73 (2006). PubMed

Pajer, P. - Pečenka, V. - Králová, J. - Karafiát, V. - Průková, D. - Zemanová, Z. - Kodet, R. - Dvořák, M.
Identification of Potential Human Oncogenes by Mapping the Common Viral Integration Sites in Avian Nephroblastoma.
Cancer Res, 66 [1] 78- 86 (2006). PubMed

2005

Bartková, J. - Hořejší, Z. - Koed, K. - Kramer, A. - Tort, F. - Zieger, K. - Guldberg, P. - Sehested, M. - Nesland, J.M. - Lukas, C. - Orntoft, T. - Lukas, J. - Bartek, J.
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Nature, 434 [-] 864-870 (2005). PubMed

Brdička, T. - Kadleček, T.A. - Roose, J.P. - Pastuszak, A.W. - Weiss, A.
Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases.
Mol. Cell Biol., 25 [-] 4924-33 (2005). PubMed

Cígler P. - Kožíšek M. - Řezáčová P. - Brynda J. - Otwinowski Z. - Pokorná J. - Plešek J. - Grüner B. - Dolečková-Marešová L. - Máša M. - Sedláček J. - Bodem J. - Kraeusslich H.-G. - Král V. - Konvalinka J.
From non-peptide towards non-carbon protease inhibitors: metallacarboranes as specific and potent inhibitors of HIV protease.
Proc. Natl. Acad. Sci. U.S.A., 102 [-] 15394-9 (2005). PubMed

Divina, P. - Vlcek, C. - Strnad, P. - Paces, V. - Forejt, J.
Global transcriptome analysis of the C57BL/6J mouse testis by SAGE: evidence for nonrandom gene order.
BMC Genomics, 6 [1] 29 (2005). PubMed

Dráber, P. - Dráberová, L.
Lifting the fog in store-operated Ca2+ entry.
Trends Immunol., 26 [-] 621-624 (2005). PubMed

Drosopoulos, K.G. - Roberts,M.L. - Cermak, L. - Sasazuki, T. - Shirasawa, S. - Andera, L. - Pintzas, A.
Transformation by Oncogenic RAS Sensitizes Human Colon Cells to TRAIL-induced Apoptosis by Up-regulating Death Receptor 4 and Death Receptor 5 through a MEK-dependent Pathway.
J. Biol. Chem., 280 [-] 22856-22867 (2005). PubMed

Elleder, D. - Stepanets, V. - Melder, D.C. - Šenigl, F. - Geryk, J. - Pajer, P. - Plachý, J. - Hejnar, J. - Svoboda, J.
Federspiel, M.J.: The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily.
J. Virol., 79 [-] 10408-10419 (2005). PubMed

Grinchuk., O. - Kozmik, Z. - Wu, X. - Tomarev, S.
The Optimedin gene is a downstream target of Pax6.
J Biol Chem., 280 [-] 35228-37 (2005). PubMed

Jansa, P. - Divina, P. - Forejt, J.
Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain).
BMC Genomics, 6 [-] 161 (2005). PubMed

Kaspar, P. - Pajer, P. - Sedlak, D. - Tamaoki, T. - Dvorak, M.
c-Myb inhibits myogenic differentiation through repression of MyoD.
Exp Cell Res, 309 [-] 419-428 (2005). PubMed

Koc, M. - Nad'ova, Z. - Truksa, J. - Ehrlichova, M. - Kovar, J.
Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation.
Apoptosis, 10 [-] 381-93 (2005). PubMed

Kozmik, Z.
Pax genes in eye development and evolution.
Curr Opin Genet Dev., 15 [-] 430-8 (2005). PubMed

Lipoldová, M. - Havelková, H. - Badalová, J. - Demant P.
Novel loci controlling lymphocyte proliferative response to cytokines and their clustering with loci controlling autoimmune reactions, macrophage functions, and lung tumor susceptibility.
Int. J. Cancer, 114 [3] 394-399 (2005). PubMed

Vacík, T. - Ort, M. - Gregorová, S. - Strnad, P. - Blatný, R. - Conte, N. - Bradley, A. - Bureš, J. - Forejt. J.
Segmental trisomy of chromosome 17 – a mouse model of human aneuploidy syndromes.
Proc. Natl. Acad. Sci. U.S.A., 102 [-] 4500-4505 (2005). PubMed

Wang, Y. - Horváth, O. - Hamm-Baarke, A. - Richelme, M. - Gregoire, C. - Guinamard, R. - Hořejší, V. - Angelisová, P. - Špička, J. - Schraven, B. - Malissen, B. - Malissen, M.
Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function.
Mol. Cell Biol., 25 [-] 4455-65 (2005). PubMed

2004

Brynda, J. - Řezáčová, P. - Fábry, M. - Hořejší, M. - Štouračová, R. - Sedláček, J. - Souček, M. - Hradílek, M. - Lepšík, M. - Konvalinka, J.
A Phenylnorstatine Inhibitor Binding to HIV-1 Protease: Geometry, Protonation, and Subsite-Pocket Interactions Analyzed at Atomic Resolution.
Journal of Medicinal Chemistry, 47 [8] 2030-2036 (2004). PubMed

Divina, P. - Forejt, J.
The Mouse SAGE Site: database of public mouse SAGE libraries.
Nucleic Acids Research, 32, [-] D482-D483 (2004). PubMed

Dráberová, L. - Lebduška, P. - Hálová, I. - Tolar, P. - Štokrová, J. - Tolarová, H. - Korb, J. - Dráber, P.
Signaling assemblies formed in mast cells activated via Fce receptor I dimers.
European Journal of Immunology, 34 [8] 2209-2219 (2004). PubMed

Drábková, L. - Kirschner, J. - Vlček, Č. - Pačes, V.
TrnL-trnF intergenetic spacer and trnL intron define major clades within Luzula and Juncus (Juncaceae): Importance of structural mutations.
Journal of Molecular Evolution, 59, [-] 1-10 (2004). PubMed

Elleder, D. - Melder, D. C. - Trejbalová, K. - Svoboda, J. - Federspiel, M.
Two different molecular defects in the Tva receptor gene explain the resistance to two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses.
Journal of Virology, 78 [24] 13489-13500 (2004). PubMed

Hořejší, V. - Zhang, W. - Schraven, B.
Transmembrane adaptor proteins: organizers of immunoreceptor signalling.
Nature Reviews Immunology, 4 [8] 603-616 (2004). PubMed

Krásný, L. - Gourse, R. L.
An alternative strategy for bacterial ribosome synthesis: Bacillus subtilis rRNA transcription regulation.
EMBO Journal, 23 [22] 4473-4483 (2004). PubMed

Kukharskyy, V. - Sulimenko, V. - Macůrek, L. - Sulimenko, T. - Dráberová, E. - Dráber, P.
Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells.
Experimental Cell Research, 298, [-] 218-228 (2004). PubMed

Lusková, P. - Dráber, P.
Modulation of the Fcepsilon receptor I signaling by tyrosine kinase inhibitors: search for therapeutic targets of inflammatory and allergy diseases.
Current Pharmaceutical Design, 10 [15] 1727-1736 (2004). PubMed

Libusová, L. - Sulimenko, T. - Sulimenko, V. - Hozák, P. - Dráber, P.
Gamma-tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms.
Experimental Ccell Research, 295, [-] 375-386 (2004). PubMed

Malý, P. - Marková, V. - Škopková, Z. - Jeníková, G. - Kalaninová, J. - Láchová, J.
Molecular cloning, tissue distribution and construction of recombinant forms of the mouse galectin-4 and galectin-6.
Glycobiology, 14 [11] 1109-1109 (2004).

Pastoreková, S. - Závada, J.
Carbonic anhydrase IX (CA IX) as a potential target for cancer therapy. Rewiev article.
Cancer Therapy, 2, [-] 245-262 (2004).

Šanderová, H. - Hůlková, M. - Maloň, P. - Kepková, M. - Jonák, J.
Thermostability of Multidomain Proteins: Elongation Factors EF-Tu from Escherichia coli and Bacillus stearothermophilus and Their Chimeric Forms.
Protein Science, 13 [1] 89-99 (2004). PubMed

Tolar, P. - Dráberová, L. - Tolarová, H. - Dráber, P.
Positive and negative regulation of Fcepsilon receptor I-mediated signaling events by Lyn kinase C-terminal tyrosine phosphorylation.
European Journal of Immunology, 34 [4] 1136-1145 (2004). PubMed

Tolarová, H. - Dráberová, L. - Heneberg, P. - Dráber, P.
Involvement of filamentous actin in setting the threshold for degranulation in mast cells.
European Journal of Immunology, 34 [6] 1627-1636 (2004). PubMed

Volná, P. - Lebduška, P. - Dráberová, L. - Šímová, Š. - Heneberg, P. - Boubelík, M. - Bugajev, V. - Mallisen, B. - Wilson, B. S. - Hořejší, V. - Mallisen, M. - Dráber, P.
Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.
Journal of Experimental Medicine, 200 [8] 1001-1013 (2004). PubMed

Zavadil, J.* - Čermák, L.* - Soto-Nieves, N. - Bottinger, E. P.
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition.
EMBO Journal, 23, [-] 1155-1165 (2004). PubMed

2003

Bartůněk, P. - Králová, J. - Blendiger, G. - Dvořák, M. - Zenke, M.
GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.
Oncogene, 22 [13] 1927-1935 (2003). PubMed

Brdičková, N. - Brdička, T. - Angelisová, P. - Horváth, O. - Špička, J. - Hilgert, I. - Pačes, J. - Simeoni, L. - Kliche, S. - Merten, C. - Schraven, B. - Hořejší, V.
LIME: a new membrane raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling.
Journal of Experimental Medicine, 198 [10] 1453-1462 (2003). PubMed

Bubeník, J. - Mikyšková, R. - Vonka, V. - Mendoza, L. - Šímová, J. - Šmahel, M. - Indrová, M.
Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16.
Vaccine, 21 [9-10] 891-896 (2003). PubMed

Dráberová, L. - Dudková, L. - Boubelík, M. - Tolarová, H. - Šmíd, F. - Dráber, P.
Exogenous administration of gangliosides inhibits FcepsilonRI-mediated mast cell degranulation by decreasing the activity of phospholipase Cgamma.
Journal of Immunology, 171 [7] 3585-3593 (2003). PubMed

Hořejší, V.
The roles of membrane microdomains (rafts) in T cell activation.
Immunological Reviews, 191, [-] 148-164 (2003). PubMed

Králová, J. - Dvořák, M. - Král, V.
Novel cationic transport agents for oligonucleotide delivery into primary leukemic cells.
Journal of Medicinal Chemistry, 46 [11] 2049-2056 (2003). PubMed

Pajer, P. - Pečenka, V. - Karafiát, V. - Králová, J. - Hořejší, Z. - Dvořák, M.
The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma.
Oncogene, 22 [5] 665-673 (2003). PubMed

Vacík, T. - Forejt, J.
Quantification of expression and methylation of the Igf2r imprinted gene in segmental trisomic mouse model.
Genomics, 82, [-] 261-268 (2003). PubMed

Valenta, T. - Lukáš, J. - Kořínek, V.
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells.
Nucleic Acids Research, 31 [9] 2369-2380 (2003). PubMed

Vladimirov, V. - Badalová, J. - Svobodová, M. - Havelková, H. - Hart, A. A. M. - Blažková, H. - Demant, P. - Lipoldová, M.
Different genetic control of cutaneous and visceral disease after Leishmania major infection in mice.
Infection and Immunity, 71 [4] 2041-2046 (2003). PubMed

Vojtěchová, M. - Šloncová, E. - Kučerová, D. - Jiřička, J. - Sovová, V. - Tuháčková, Z.
Initiation factor eIF2B not p70 S6 kinase is involved in the activation of the PI-3K signalling pathway induced by the v-src oncogene.
FEBS Letters, 543, 81-86 (2003). PubMed

Závada, J. - Závadová, Z. - Zaťovičová, M. - Hyršl, L. - Kawaciuk, I.
Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients.
British Journal of Cancer, 89, [-] 1067-1071 (2003). PubMed

2002

Bartůněk, P. - Pajer, P. - Karafiát, V. - Blendinger, G. - Dvořák, M. - Zenke, M.
bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.
Oncogene, 21 [3] 400-410 (2002). PubMed

Brdička, T. - Imrich, M. - Angelisová, P. - Brdičková, N. - Horváth, O. - Špička, J. - Hilgert, I. - Lusková, P. - Dráber, P. - Novák, P. - Engels, N. - Wienands, J. - Simeoni, L. - Osterreicher, J. - Aguado, E. - Malissen, M. - Schraven, B. - Hořejší, V.
NTAL (non-T cell activation linker):a transmembrane adaptor protein involved in immunoreceptor signaling.
Journal of Experimental Medicine, 196 [12] 16180-16185 (2002). PubMed

Čermák, L. - Šímová, Š. - Pintzas, A. - Hořejší, V. - Anděra, L.
Apoptosis of TF-1 cells induced by engagement of CD43: roles of transcription, expression of Daxx and adhesion molecules.
Journal of Biological Chemistry, 277 [10] 7955-7961 (2002). PubMed

Dohnálek, J. - Hašek, J. - Dušková, J. - Petroková, H. - Hradilek, M. - Souček, M. - Konvalinka, J. - Brynda, J. - Sedláček, J. - Fábry, M.
Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor.
Journal of Medicinal Chemistry, 45 [7] 1432-1438 (2002). PubMed

Elleder, D. - Pavlíček, A. - Pačes, J. - Hejnar, J.
Preferential integration of human immunodeficiency virus type 1 into genes, cytogenetic R bands and GC-rich DNA regions: insight from the human genome sequence.
FEBS Letters, 517 [1-3] 285-286 (2002). PubMed

Hořejší, V.
Membrane rafts in immunoreceptor signaling: new doubts, new proofs?
Trends in Immunology, 23 [12] 562-564 (2002). PubMed

Králová, J. - Liss, A. S. - Bargmann, W. - Pendleton, C. - Varadarajan, J. - Ulug, E. - Bose, H. R. Jr.
Differential regulation of the inhibitor of the apoptosis ch-IAP1 by v-rel and proto-oncogene c-rel.
Journal of Virology, 76 [23] 11960-11970 (2002). PubMed

Lácha, J. - Bushell, A. - Smetana, K. - Rossmann, P. - Přibylová, P. - Wood, K. - Malý, P.
Intercellular cell adhesion molecule-1 and selectin ligands in acute cardiac allograft rejection: a study on gene-deficient mouse models.
Journal of Leukocyte Biology, 71, [-] 311-318 (2002). PubMed

Pačes, J. - Pavlíček, A. - Pačes, V.
HERVd: database of human endogenous retroviruses.
Nucleic Acids Research, 30 [1] 205-206 (2002). PubMed

Pavlíček, A. - Clay, O. - Jabbari, K. - Pačes, J. - Bernardi, G.
Isochore conservation between MHC regions on human chromosome 6 and mouse chromosome 7.
FEBS Letters, 511 [1-3] 175-177 (2002). PubMed

Pavlíček, A. - Pačes, J. - Clay, O. - Bernardi, G.
A compact view of isochores in the draft human genome sequence.
FEBS Letters, 511 [1-3] 165-169 (2002).PubMed

Pavlíček, A. - Pačes, J. - Elleder, D. - Hejnar, J.
Processed pseudogenes of human endogenous retroviruses generated by LINEs: their integration, stability, and distribution.
Genome Research, 12 [3] 391-399 (2002). PubMed

Sulimenko, V. - Sulimenko, T. - Poznanovic, S. - Nechiporuk-Zloy, V. - Bohm, K. - Macůrek, L. - Unger, E. - Dráber, P.
Association of brain tubulins with tubulin dimers.
Biochemical Journal, 365 [3] 889-895 (2002). PubMed

2001

Brdičková, N. - Brdička, T. - Anděra, L. - Špička, J. - Angelisová, P. - Milgram, S. L. - Hořejší, V.
Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton.
FEBS Letters, 507 [2] 133-136 (2001). PubMed

Drbal, K. - Angelisová, P. - Hilgert, I. - Černý, J. - Novák, P. - Hořejší, V.
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
Blood, 98 [5] 1561-1566 (2001). PubMed

Hejnar, J. - Hájková, P. - Plachý, J. - Elleder, D. - Stepanets, V. - Svoboda, J.
CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression.
Proceedings of the National Academy of Sciences, 98 [2] 565-569 (2001). PubMed

Karafiát, V. - Dvořáková, M. - Pajer, P. - Králová, J. - Hořejší, Z. - Čermák, V. - Bartůněk, P. - Zenke, M. - Dvořák, M.
The leucine zipper region of Myb oncoprotein regulates commitment of hematopoietic progenitors.
Blood, 98, 3668-3676 (2001). PubMed

Kovářová, M. - Tolar, P. - Arudchandran, R. - Dráberová, L. - Rivera, J. - Dráber, P.
Structure-function analysis of Lyn kinase association with lipid rafts and intiation of early signaling events after Fc epsilon receptor I aggregation.
Molecular and Cell Biology, 21 [24] 8318-8328 (2001). PubMed

Kozmik, Z. - Machoň, O. - Krešlová, J. - Pačes, J. - Vlček, Č.
Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.
Genomics, 73 [2] 140-148 (2001). PubMed

Kratzerová, L. - Dráberová, E. - Juliano, C. - Viklický, V. - Fiori, P. L. - Cappuccinelli, P. - Dráber, P.
Cell cycle-dependent changes in localization of a 210-kDa microtubule-interacting protein in Leishmania.
Experimental Cell Research, 266 [2] 270-278 (2001). PubMed

Pěknicová, J. - Kubátová, A. - Sulimenko, V. - Dráberová, E. - Viklický, V. - Hozák, P. - Dráber, P.
Differential subcellular distribution of tubulin in boar spermatozoa: Recognition of class III beta-tubulin epitope in sperm tail.
Biology of Reproduction, 65 [3] 672-679 (2001). PubMed

Řezáčová, P. - Lescar, J. - Brynda, J. - Fábry, M. - Hořejší, M. - Sedláček, J. - Bentley, G.
Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody.
Structure, 9 [10] 887-895 (2001). PubMed

Říman, J.
A DNA polymerase epsilon inhibitor activates the ribo and deoxyribo modes of primase expression and induces a unique phenomenon of primer accumulation.
FEBS Letters, 505 [1] 141-146 (2001). PubMed

Surviladze, Z. - Dráberová, L. - Kovářová, M. - Boubelík, M. - Dráber, P.
Differential sensitivity to acute cholesterol lowering of activation mediated via the high-affinity IgE receptor and Thy-1 glycoprotein.
European Journal of Immunology, 31 [1] 1-10 (2001). PubMed

2000

Binarová, P. - Cenklová, V. - Hause, B. - Kubátová, E. - Lysák, M. - Doležel, J. - Bögre, L. - Dráber, P.
Nuclear Gamma-Tubulin during Acentriolar Plant Mitosis.
Plant Cell, 12 [3] 433-442 (2000). PubMed

Brdička, T. - Pavlištová, D. - Leo, A. - Bruyns, E. - Kořínek, V. - Angelisová, P. - Scherer, J. - Shevchenko, A. - Shevchenko, A. Jr. - Hilgert, I. - Černý, J. - Drbal, K. - Kuramitsu, Y. - Kornacker, B. - Hořejší, V. - Schraven, B.
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase Csk and is involved in regulation of T cell activation.
Journal of Experimental Medicine, 191 [9] 1591-1604 (2000). PubMed

Havelková, H. - Badalová, J. - Demant, P. - Lipoldová, M.
A new type of genetic regulation of allogeneic response. A novel locus on mouse chromosome 4, Alan2 controls MLC reactivity to three different alloantigens: C57BL/10, BALB/c and CBA.
Genes and Immunity, 1 [8] 483-487 (2000). PubMed

Kmoch, S. - Brynda, J. - Asfaw, B. - Bezouska, K. - Novak, P. - Rezacova, P. - Ondrova, L. - Filipec, M. - Sedlacek, J. - Elleder, M.
Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography.
Human Molecular Genetics, 9 [12] 1779-1786, 2000. PubMed

Krásný, L. - Vacík, T. - Fučík, V. - Jonák, J.
Cloning and characterization of the str operon and elongation factor Tu expression in Bacillus stearothermophilus.
Journal of Bacteriology, 182 [21] 6114-6122 (2000). PubMed

Lipoldová, M. - Svobodová, M. - Krulová, M. - Havelková, H. - Badalová, J. - Nohýnková, E. - Holáň, V. - Hart, A. - Volf, P. - Demant, P.
Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes.
Genes and Immunity, 1 [3] 200-206 (2000). PubMed

Závada, J. - Závadová, Z. - Pastorek, J. - Biesova, Z. - Ježek, J. - Velek, J.
Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitopes and of the region mediating cell adhesion.
British Journal of Cancer, 82 [11] 1808-1813 (2000). PubMed

Zídek, Z. - Franková, D. - Boubelík, M.
Genetic variation in in-vitro cytokine-induced production of nitric oxide by murine peritoneal macrophages.
Pharmacogenetics, 10 [6] 493-501 (2000). PubMed

Zíková, M. - Sulimenko, V. - Dráber, P. - Dráberová, E.
Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells.
FEBS Letters, 473 [1] 19-23 (2000). PubMed

1999

Angelisová, P. - Drbal, K. - Hořejší, V. - Černý, J.
Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in GPI-anchored proteins and Lyn kinase.
Blood, 93, 1437-1439 (1999). PubMed

Dráberová, L. - Dráberová, E. - Surviladze, Z. - Dráber, P. - Dráber, P.
Protein tyrosine kinase p53/p56^lynforms complexes with G-tubulin in rat basophilic leukemia cells.
International Immunology, 11 [11] 1829-1839 (1999). PubMed

Drbal, K. - Angelisová, P. - Rasmussen, A. M. - Hilgert, I. - Funderud, S. - Hořejší, V.
The nature of the subset of MHC class II molecules carrying the CDw78 epitopes.
International Immunology, 11 [4] 491-498 (1999). PubMed

Forejt, J. - Saam, J. R. - Gregorová, S. - Tilghman, S. M.
Monoallelic expression of reactivated imprinted genes in embryonal carcinoma cell hybrids.
Experimental Cell Research, 252 [2] 416-422 (1999). PubMed

Havelková, H. - Kosařová, M. - Krulová, M. - Holáň, V. - Demant, P. - Lipoldová, M.
T-cell proliferative response is controlled by locus Tria 3on mouse chromosome 17.
Immunogenetics, 49 [3] 235-237 (1999). PubMed

Hořejší, V. - Drbal, K. - Cebecauer, M. - Černý, J. - Brdička, T. - Angelisová, P. - Stockinger, H.
GPI-microdomains: a role in signalling via immunoreceptors.
Immunology Today, 20 [8] 356-361 (1999). PubMed

Kašpar, P. - Dvořáková, M. - Králová, J. - Pajer, P. - Kozmik, Z. - Dvořák, M.
Myb-interacting Protein, ATBF1, Represses Transcriptional Activity of Myb Oncoprotein.
Journal of Biological Chemistry, 274 [20] 14422-14428 (1999). PubMed

Lescar, J.* - Brynda, J.* - Řezáčová, P. - Štouračová, R. - Riottot, M. M. - Chitarra, V. - Fábry, M. - Hořejší, M. - Sedláček, J. - Bentley, G. A.
Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.
Protein Science, 8 [12] 2686-2696 (1999). PubMed

Pečenková, T. - Pačes, V.
Molecular Phylogeny of f29-like Phages and Their Evolutionary Relatedness to Other Protein-Primed Replicating Phages and Other Phages Hosted by Gram-Positive Bacteria.
Journal of Molecular Evolution, 48, 197-208 (1999). PubMed

Plachý, J. - Weining, K. C. - Kremmer, E. - Puehler, F. - Hála, K. - Kaspers, B. - Staeheli, P.
Protective Effects of Type I and Type II Interferons toward Rous Sarcoma Virus-Induced Tumors in Chickens.
Virology, 256, 85-91 (1999). PubMed

Štokrová, J. - Palková, Z. - Fischer, L. - Richterová, Z. - Korb, J. - Griffin, B. E. - Forstová, J.
Interactions of heterologous DNA with polyomavirus major structural protein, VP1.
FEBS Letters, 445 [1] 119-125 (1999). PubMed

Trachtulec, Z. - Forejt, J.
Transcription and RNA processing of mammalian genes in Saccharomyces cerevisiae.
Nucleic Acids Research, 27, 526-531 (1999). PubMed

Tuháčková, Z. - Sovová, V. - Šloncová, E. - Proud, C. G.
Rapamycin-resistant phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in v-src-transformed hamster fibroblasts.
International Journal of Cancer, 81 [6] 963-969 (1999). PubMed

1998

Binarová, P. - Hause, B. - Doležel, J. - Dráber, P.
Association of G-tubulin with kinetochore/centromeric region of plant chromosomes.
Plant Journal, 14 [6] 751-757 (1998).

Boubelík, M. - Floryk, D. - Bohata, J. - Dráberová, L. - Mačák, J. - Šmíd, F. - Dráber, P.
Lex glycosphingolipids-mediated cell aggregation.
Glycobiology, 8 [2] 139-146 (1998). PubMed

Holáň, V. - Kuffová, L. - Zajícová, A. - Krulová, M. - Filipec, M. - Holler, P. - Jančárek, A.
Urocanic Acid Enhances IL-10 Production in Activated CD4+=T Cells.
Journal of Immunology, 161, 3237-3241 (1998). PubMed

Jonák, J. - Anborgh, P. H. - Parmeggiani, A.
Interaction of EF-Tu with EF-Ts: substitution of His-118 in EF-Tu destabilizes the EF-Tu.EF-Ts complex but does not prevent EF-Ts from stimulating the release of EF-Tu-bound GDP.
FEBS Letters, 422 [2] 189-192 (1998). PubMed

Králová, J. - Liss, A. S. - Bargmann, W. - Bose, H. R.
AP-1 Factors Play an Important Role in Transformation Induced by the v-rel Oncogene.
Molecular and Cellular Biology, 18 [5] 2997-3009 (1998). PubMed

Krásný, L. - Mesters, J. R. - Tieleman, L. N. - Kraal, B. - Fučík, V. - Hilgenfeld, R. - Jonák, J.
Structure and Expression of Elongation Factor Tu from Bacillus stearothermophilus.
Journal of Molecular Biology, 283 [2] 371-381 (1998). PubMed

Surviladze, Z. - Dráberová, L. - Kubínová, L. - Dráber, P.
Functional heterogeneity of Thy-1 membrane microdomains in rat basophilic leukemia cells.
European Journal of Immunology, 28 [6] 1847-1858 (1998). PubMed

1997

Amoui, M. - Dráberová, L. - Tolar, P. - Dráber, P.
Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fce receptors.
European Journal of Immunology, 27 [2] 321-328 (1997). PubMed

Amoui, M. - Dráber, P. - Dráberová, L.
Src family-selective tyrosine kinase inhibitor, PP1, inhibits both FceRI- and Thy-1-mediated activation of rat basophilic leukemia cells.
European Journal of Immunology, 27, 1881-1886 (1997). PubMed

Bartůněk, P. - Karafiát, V. - Dvořáková, M. - Záhorová, V. - Mandíková, S. - Zenke, M. - Dvořák, M.
The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein.
Oncogene, 15 [24] 2939-2949 (1997). PubMed

Černý, J. - Fišerová, A. - Horváth, O. - Bezouška, K. - Pospíšil, M. - Hořejší, V.
Association of human NK cell surface receptors NKR-P1 and CD94 with Src-family protein kinases.
Immunogenetics, 46 [3] 231-236 (1997). PubMed

Klein, J. - Hořejší, V.
Immunology 2nd edition. Oxford, Blackwell Science 1997. - 722 s. (book)

Krulová, M. - Havelková, H. - Kosařová, M. - Holáň, V. - Hart, A. A. M. - Demant, P. - Lipoldová, M.
IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: A distinct control of the response induced by different IL-2 concentrations.
Genomics, 42 [1] 11-15 (1997). PubMed

Lescar, J. - Štouračová, R. - Riottot, M. M. - Chitarra, V. - Brynda, J. - Fábry, M. - Hořejší, M. - Sedláček, J. - Bentley, G. A.
Three-dimensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
Journal of Molecular Biology, 267 [5] 1207-1222 (1997). PubMed

Tolar, P. - Dráberová, L. - Dráber, P.
Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells.
European Journal of Immunology, 27, 3389-3397 (1997). PubMed

Trachtulec, Z. - Hamvas, R. M. J. - Forejt, J. - Lehrach, H. R. - Vincek, V. - Klein, J.
Linkage of TATA-Binding Protein and Proteasome Subunit C5 Genes in Mice and Humans Reveals Synteny Conserved between Mammals and Invertebrates.
Genomics, 44, 1-7 (1997). PubMed

Urbánek, P. - Fetka, I. - Meisler, M. H. - Busslinger, M.
Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Proceedings of the National Academy of Sciences of the USA, 94, 5703-5708 (1997). PubMed

Vlček, Č. - Pačes, V. - Maltsev, N. - Pačes, J. - Haselkorn, R. - Fonstein, M.
Sequence of a 189-kb segment of the chromosome of Rhodobacter capsulatus SB 1003.
Proceedings of the National Academy of Sciences of the USA, 94 [ 17] 9384-9388 (1997). PubMed

1996

Briešťanská, J. - Plachý, J.
Influence of the transduced 3'UTR of the c-src oncogene on tumour growth induced by the v-src gene of avian sarcoma virus PR2257.
Journal of General Virology, 77, 1189-1192 (1996).PubMed

Bubeník, J.
Cytokine gene-modified vaccines in the therapy of cancer.
Pharmacology and Therapeutics, 69 [1] 1-14 (1996). PubMed

Bubeník, J.
Gene transfer for immunotherapy of cancer.
Gene Therapy, 3 [11] 944-945 (1996).

Černý, J. - Stockinger, H. - Hořejší, V.
Noncovalent association of T lymphocyte surface proteins.
European Journal of Immunology, 26 [10] 2335-2343 (1996). PubMed

Forejt, J.
Hybrid Sterility in the Mouse
Trends in Genetics, 12 [10] 412-417 (1996). PubMed

Havelková, H. - Krulová, M. - Kosařová, M. - Holáň, V. - Hart, A. A. M. - Demant, P. - Lipoldová, M.
Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15.
Immunogenetics, 44 [6] 475-477 (1996).

Holáň, V. - Lipoldová, M. - Demant, P.
Identical genetic control of MLC reactivity to different MHC incompatibilities, independent of production of and response to IL-2.
Immunogenetics, 44 [1] 27-35 (1996). PubMed

Jansa, P. - Forejt, J.
A novel type of retinoic acid response element in the second intron of the mouse H2Kb gene is activated by the RAR/RXR heterodimer.
Nucleic Acids Research, 24, 694-701 (1996).PubMed

1995

Bohuslav, J. - Hořejší, V. - Hansmann, C. - Stöckl, J. - Weidle, U. - Majdic, O. - Bartke, I. - Knapp, W. - Stockinger, H.
Urokinase plasminogen activator receptor, B2-integrins, and Src-kinases within a single receptor of human monocytes.
Journal of Experimental Medicine, 181, 1381-1390 (1995). PubMed

Brynda, J. - Fábry, M. - Hořejší, M. - Sedláček, J.
The Gag-Pol Encoded Proteinase of an Avian Retrovirus Expressed in Esterichia coli Can Produce a Novel Proteinase (PR+IleGly) That Is Two Amino Acids Larger at Its Carboxy-Terminal Region Than the Major Gag Proteinase (PR).
Virology, 207 [1] 185-190 (1995).PubMed

Cinek, T. - Hilgert, I. - Hořejší, V.
An alternative way of CD4 and CD8 association with protein kinases of the Src family.
Immunogenetics, 41, 110-116 (1995). PubMed

Dráberová, L. - Dráber, P.
Thy-1-mediated activation of rat basophilic leukemia cells does not require co-expression of the high-affinity IgE receptor.
European Journal of Immunology, 25, 2428-2432 (1995). PubMed

Lipoldová, M. - Kosařová, M. - Zajícová, A. - Holáň, V. - Hart, A. A. M. - Krulová, M. - Demant, P.
Separatiom of multiple genes controlling the T cell proliferative response to IL-2 and anti-CD3 using Recombinant Congenic Strains.
Immunogenetics, 41, 301-311 (1995). PubMed

Vlček, Č. - Beneš, V. - Pačes, V. - Lu, Y. - Kutish, G. F. - Rock, D. - Letchworth, G. J. - Schwyzer, M.
Nucleotide sequence analysis of a 30-kb region of the bovine herpesvirus 1 genome which exhibits a colinear gene arrangement with the UL21 to UL4 genes of herpes simplex virus.
Virology, 210, 100-108 (1995). PubMed

Vlček, Č. - Langlois, I. - Styger, D. - Vogt, B. - Simard, C. - Chaligour, A. - Trudel, M. - Schwyzer, M.
Sequence analysis of the UL39, UL38 and UL37 homologues of bovine herpesvirus 1 and expression studies of UL40 and U L39. The subunits of ribonucleotide reductase.
Virology, 212, 734-740 (1995). PubMed

webmaster

office