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Monoclonal antibodies available from the Laboratory of molecular immunology
The specificities of the mAbs marked as (W) were verified by international HLDA workshops.
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Antigen |
Antibody |
Isotype |
Note |
|
CD2 |
MEM-65 (W) |
IgG1 |
unique epitope |
|
|
MEM-69 |
IgG1 |
|
|
CD3 (e) |
MEM-57 (W) |
IgG2a |
can be used clinically (immunosuppression) |
|
|
MEM-92 (W) |
IgM |
activating |
|
CD4 |
MEM-16 (W) |
IgM |
epitope in D1-D2 |
|
|
MEM-115 (W) |
IgG2a |
epitope in D1; blocks gp120 |
|
|
MEM-241 |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-242 |
IgG1 |
weakly positive in W. blotting (non-red.) |
|
CD5 |
MEM-32 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-128 (W) |
IgM |
|
|
|
MEM-247 |
IgG1 |
positive in W. blotting (non-red.) |
|
CD6 |
MEM-98 |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-100 |
IgG1 |
|
|
CD7 |
MEM-186 (W) |
IgG |
positive in W. blotting (non-red.) |
|
CD8 |
MEM-31 (W) |
IgG2a |
|
|
|
MEM-87 (+ several others) |
IgG1 |
epitope similar to MEM-31 |
|
|
MEM-146 (W) |
IgG1 |
epitope different from MEM-31 |
|
CD9 |
MEM-62 (W) |
IgG1 |
|
|
|
MEM-192 (W) |
IgM |
positive in W. blotting (non-red.) |
|
CD10 (CALLA) |
MEM-78 (W) |
IgG1 |
positive in W. blotting (nen-red.) |
|
CD11a (LFA-1a) |
MEM-25 (W) |
IgG1 |
|
|
|
MEM-30 (W) |
IgG1 |
|
|
|
MEM-83 (W) |
IgG1 |
activates LFA-1 (to high affinity) |
|
|
MEM-94 |
IgG1 |
blocks binding to ICAM-1 |
|
|
MEM-95 (W) |
IgG1 |
blocks binding to ICAM-1 |
|
|
MEM-144 |
IgG1 |
|
|
|
MEM-152 |
IgG2b |
|
|
|
MEM-177 |
IgG1 |
epitope similar to MEM-83 |
|
CD11b |
MEM-170 (W) |
IgG1 |
blocks binding to ICAM-1 |
|
|
MEM-174 (W) |
IgG2a |
|
|
CD14 |
MEM-15 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-18 (W) |
IgG1 |
positive in W. blotting (non-red.) blocks binding of LPS-LBP to CD14 |
|
CD15 |
MEM-157 |
IgM |
|
|
|
MEM-158 |
IgM |
|
|
|
MEM-167 |
IgM |
|
|
CD16 |
MEM-154 (W) |
IgG1 |
positive in W. blotting (non-red.) recognizes a polymorphism in CD16A (NK-form) |
|
|
MEM-168 |
IgM |
|
|
CD17 |
MEM-74 (W) (+ several others) |
IgM |
|
|
CD18 (LFA-1b) |
MEM-48 |
IgG1 |
positive in W. blotting (non-red.) induces high-affinity state of LFA-1 |
|
|
MEM-148 |
IgG1 |
unique epitope accessible in free CD18 only; activating mAb |
|
CD20 |
MEM-97 (W) |
IgG1 |
|
|
CD22b |
MEM-01 |
IgG1 |
positive in W. blotting (non-red.) |
|
CD25 |
MEM-140 (W) |
IgM |
|
|
|
MEM-141 |
IgM |
|
|
|
MEM-145 (W) |
IgM |
|
|
|
MEM-181 (W) |
IgG1 |
|
|
CD29 |
MEM-101A (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
CD30 |
MEM-268 |
IgG |
positive in W. blotting (non-red.) |
|
CD31 |
MEM-05 |
IgG1 |
|
|
CD41 |
MEM-06 |
IgG1 |
|
|
CD43 |
MEM-59 (W) |
IgG1 |
sialic acid-dependent epitope positive in W. blotting |
|
|
MEM-256 |
IgG1 |
positive in W. blotting (non-red.); (atypical-epitope absent in myeloid cells) |
|
|
MEM-257 |
IgG1 |
positive in W. blotting (non-red.) |
|
CD44 |
MEM-85 (W) |
IgG2b |
positive in W. blotting (non-red.) |
|
|
MEM-263 |
IgG1 |
strongly positive in W. blotting |
|
CD45 |
MEM-28 (W) (+ several others) |
IgG1 |
positive in W. blotting (red., non-red.) positive in paraffin sections |
|
CD45RA |
MEM-56 (W) |
IgG2b |
positive in W. blotting |
|
|
MEM-93 (W) |
IgG1 |
as MEM-56 |
|
|
MEM-109 (+ several others) |
IgG1 |
|
|
|
|
|
|
|
CD45RB |
MEM-55 (W) |
IgG1 |
carbohydrate-dependent epitope |
|
|
MEM-143 |
IgG1 |
|
|
CD46 |
MEM-258 |
IgG2a |
positive in W. blotting (non-red.) |
|
CD47 |
MEM-122 (W) |
IgM |
|
|
|
MEM-120 (W) |
IgM |
low affinity |
|
|
MEM-133 (W) |
Ig2a |
low affinity |
|
CD48 |
MEM-102 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-124 (W) |
IgM |
|
|
|
MEM-200 |
IgG1 |
positive in W. blotting |
|
|
MEM-201 |
IgG1 |
|
|
|
MEM-204 |
IgG3 |
|
|
|
MEM-211 |
IgG2b |
positive in W. blotting |
|
|
MEM-212 |
IgG2b |
|
|
|
MEM-213 |
IgG1 |
|
|
CD50 |
MEM-04 |
IgG1 |
epitope in D1; blocks DC-SIGN binding |
|
|
MEM-171 (W) |
IgG1 |
epitope in D2 |
|
CD53 |
MEM-53 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
CD54 (ICAM-1) |
MEM-111(W) |
IgG2a |
positive in W. blotting (non-red.) |
|
|
MEM-112 (W) |
IgG1 |
as MEM-111 but weaker |
|
CD55 (DAF) |
MEM-118 (W) |
IgM |
|
|
CD56 |
MEM-188 (W) |
IgG2a |
positive in W. blotting (non-red.) |
|
CD58 |
MEM-63 (W) |
IgG1 |
epitope in D1 |
|
CD59 |
MEM-43 (W) |
IgG2a |
positive in W. blotting (non-red.) |
|
|
MEM-43/5 (W) (+ several others) |
IgG2b |
different epitope; strong in W. blotting non-red.) |
|
|
MEM-125 (W) |
IgM |
|
|
|
MEM-129 |
IgM |
|
|
CD63 |
MEM-259 |
IgG1 |
positive in W. blotting (non-red.) |
|
CD71 (TfR) |
MEM-75 (W) |
IgG1 |
does not block transferrin binding |
|
|
MEM-105 |
IgG2a |
does not block transferrin binding |
|
|
MEM-189 (W) |
IgG1 |
positive in W. blotting (non-red.) does not block transferrin binding |
|
|
MEM-191 |
IgG |
does not block transferrin binding |
|
CD80 |
MEM-233 |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-234 |
IgG1 |
positive in W. blotting |
|
|
MEM-235 |
IgG1 |
positive in W. blotting |
|
CD97 |
MEM-180 (W) |
IgG1 |
|
|
CD98 |
MEM-108 (W) |
IgG1 |
|
|
|
MEM-156 (W) |
IgM |
|
|
CD99R |
MEM-131 (W) |
IgM |
positive in W. blotting |
|
CD105 |
MEM-223 (+ several others) |
IgG |
positive in W. blotting (non-red.) |
|
CD108 |
MEM-121 (W) |
IgM |
positive in W. blotting |
|
|
MEM-150 (W) |
IgM |
as MEM-121; higher affinity |
|
CD147 |
MEM-M6/1 (+ several others) |
IgG1 |
positive in W. blotting (non-red.) |
|
CD173 |
MEM-195 (W) |
IgM |
|
|
|
MEM-196 (W) |
IgM |
|
|
|
MEM-197 (W) |
IgM |
|
|
|
MEM-198 (W) |
IgM |
|
|
CD177 |
MEM-166 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
CD222 |
MEM-238 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
|
MEM-239 |
IgG1 |
|
|
|
MEM-240 (W) |
IgG1 |
positive in W. blotting (non-red.) |
|
CD300 |
MEM-260 |
IgG |
positive in W. blotting (non-red.) |
|
|
|
|
|
|
b2 microglobulin |
B2M-01 |
IgG2a |
positive in W. blotting (non-red.) |
|
|
B2M-02 |
IgG1 |
positive in W. blotting (non-red.) |
|
HLA-DR |
MEM-12 (+ several others) |
IgG1 |
in W. blotting recognizes only the ab dimer (non-boiled sample) |
|
HLA-DR+DP (b-chain) |
MEM-136 |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
|
MEM-138 |
IgG2a |
positive in W. blotting (non-red.; red.) |
|
HLA-DR (a-chain) |
MEM-137 |
IgG1 |
positive in W. blotting (non-red.) |
|
MHC class II, human, mouse |
SLE-01, -03, -04, -06 |
chicken IgY |
positive in W. blotting |
|
|
|
|
|
|
HLA-class I |
MEM-147 |
IgG1 |
reacts in W. blotting (non-red.) with some allelic forms; very similar to W6/32) |
|
HLA-class I |
MEM-81 |
IgG1 |
|
|
|
MEM-119 |
IgM |
|
|
|
MEM-123 |
IgG3 |
|
|
|
MEM-130 |
IgM |
|
|
|
MEM-149 |
IgG1 |
reacts with an undefined polymorphic determinant (present in most subjects) |
|
|
MEM-155 |
IgG1 |
|
|
HLA-E |
MEM-E/2 (+ several others) |
IgG |
positive in W. blotting (does not react with native molecule) |
|
|
MEM-E/6, E/7, E/8 |
IgG1 |
react with the native molecule |
|
HLA-G |
MEM-G/1 (+ several others) |
IgG1 |
positive in W. blotting and paraffin sections (does not react with native molecule) |
|
|
MEM-G/9 (+ several others) |
IgG1 |
reacts with native molecule |
|
Ig k-chains |
MEM-09 |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
|
MEM-40 |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
TCR-Vb5-related (HPB-ALL) |
MEM-262 |
IgG2a |
positive in W. blotting (non-red.; red.) |
|
Insulin (human, pig, bovine) |
IN-05 |
IgG1 |
|
|
|
IN-06 |
IgG2b |
|
|
C-peptide of human proinsulin |
C-PEP-01 |
IgG1 |
|
|
a-fetoprotein (human) |
AFP-01, 02, 03 -11,-12,-13,-14 |
all IgG1 |
different epitopes |
|
Glutamate carboxypeptidase II (GCPII) |
GCP-01, 02, 04 |
all IgG1 |
positive in W. blotting (GCP-02) |
|
Phosphotyrosine |
P-TYR-01 |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
|
P-TYR-02 |
IgG2a |
positive in W. blotting (non-red.; red.) |
|
Lck (human) |
LCK-01 (peptide 22-36) |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
Lck (human, mouse) |
LCK-04 (peptide 22-36) |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
Fyn (human and mouse) |
FYN-01 (fragment aa7-197) |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
Csk (human, mouse) |
CSK-04 (fragment aa330-450) |
IgG1 |
positive in W. blotting (non-red.; red.) |
|
SLP-76 (human) |
SLP-76/1 |
IgG1 |
Positive in
W. blotting (weak) |
|
ZAP-70 |
ZAP-70/2 |
IgG1 |
Positive in W. blotting |
|
SKAP-HOM (human and mouse) |
SKAP-HOM-01, 02, 03 |
IgG |
Positive in W. blotting, human, mouse |
|
|
|
|
|
|
TRAIL |
TRAIL-01 (+ several others) |
IgG |
positive in W. blotting; some mAbs blocking |
|
TRIM |
TRIM-01 through TRIM-10 |
IgG2a |
some positive in W. blotting, some reactive also with mouse |
|
SIT |
SIT-01 through SIT-04 |
IgG |
some positive in W. blotting, some reactive also with mouse |
|
Daxx |
DAXX-01 through DAXX-04 |
IgG |
positive in W. blotting |
|
PAG |
MEM-253 |
IgG2a |
weak in W. blotting; for IP |
|
|
MEM-255 |
IgG2a |
positive in W. blotting |
|
|
PAG-C1 |
IgG2b |
C-terminal peptide; human, mouse PAG |
|
|
PAG-C6 |
IgG2b |
C-terminal peptide; human, mouse PAG |
|
NTAL |
NAP-3 |
IgG2a |
Anti-peptide; positive in W. blotting |
|
|
NAP-7 |
IgG1 |
Positive in W. blotting (human, mouse) |
|
|
NAP-8 |
IgG1 |
Positive in W. blotting (human, mouse) |
|
LAT |
LAT-01 |
IgG1 |
Positive in W. blotting; poor with phosphorylated LAT |
|
LIME |
LIME-10 (and several others) |
IgG2a |
Positive in W. blotting |
|
EBP50 (NHERF) |
EBP-10 |
IgG2b |
Positive in W. blotting |
|
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