Department of Pharmacology

Franková, D., Zídek, Z., Buchar, E., Jiřička, Z., Holý, A.: (1999) Antiinflammatory effects of phosphonomethoxyethyl analogues of adenine in a model of adjuvant arthritis. Nucleosides Nucleotides 18(4–5): 955–958.

Zídek, Z., Franková, D., Holý, A.: (1999) Chemokines, nitric oxide and antiarthritic effects of 9-(2-phosphonomethoxyethyl)adenine (Adefovir). Eur. J. Pharmacol. 376
(1–2): 91–100.

Zídek, Z., Franková, D., Holý, A.: (1999) Stimulation of cytokine and nitric oxide production by acyclic nucleoside phosphonates. Nucleosides Nucleotides 18(4–5): 959–962.

Zídek, Z., Franková, D.: (1999) Interleukin-10 in combination with interferon-gamma and tumor necrosis factor-alpha enhances in vitro production of nitric oxide by murine resident paritoneal macrophage. Eur. Cytokine Netw. 10(1): 25–32.

Zídek, Z.: (1999) Adenosine - cyclic AMP pathways and cytokine expression. Eur. Cytokine Netw. 10(3): 319–328.

Zídek, Z.: (1999) Immunomodulatory antivirals. Drug Discovery Today 4(2): 97–98.

Mašek, K., Petrovický, P., Ševčík, J., Zídek, Z., Franková, D.: (2000) Past, present and future of psychoneuroimmunology. Toxicology 142: 179–188.

Tučková, L., Flegelová, Z., Tlaskalová-Hogenová, H., Zídek, Z.: (2000) Activation of macrophages by food antigens: enhancing effect of gluten on nitric oxide and cytokine production. J. Leukoc. Biol. 67(3): 312–318.

Zídek, Z., Franková, D., Boubelík, M.: (2000) Genetic variation in in vitro cytokine-induced production of nitric oxide by murine peritoneal macrophages. Pharmacogenetics 10: 493–501.

Zídek, Z., Franková, D., Holý, A.: (2000) Macrophage activation by antiviral acyclic nucleoside phosphonates in dependence on priming immune stimuli. Int. J. Immunopharmac. 22 (12): 1121–1129.

Trebichavský, I., Zídek, Z., Franková, D., Zahradníčková, M., Šplíchal, I.: (2001) Nitric oxide metabolites in gnotobiotic piglets orally infected with Salmonella enterica serovar typhimurium. J. Leukoc. Biol. 46: 353–358.

Zídek, Z., Franková, D., Holý, A.: (2001) Activation by 9-(R)-[2-(phosphonomethoxy)propyl]adenine of chemokine (RANTES, macrophage inflammatory protein 1alpha) and cytokine (tumor necrosis factor alpha, interleukin-10 [IL-10], IL-1beta) production. Antimicrob. Agents Chemother. 45(12): 3381–3386.

Zídek, Z.: (2001) Role of cytokines in modulation of nitric oxide production by cyclic AMP. Eur. Cytokine. Netw. 12(1): 22–32.

Tučková, L., Novotná, J., Novák, P., Flegelová, Z., Květoň, T., Jelínková, L., Zídek, Z., Man, P., Tlaskalová-Hogenová, H.: (2002) Activation of macrophages by gliadin fragments: isolation and characterization of active peptide. J. Leukoc. Biol. 71(4): 625–631.

Botros, S., William, S., Hammam, O., Zídek, Z., Holý, A.: (2003) Activity of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine against Schistosomiasis mansoni in mice. Antimicrob. Agents Chemother. 47(12): 3853–3858.

Zídek, Z., Potměšil, P., Holý, A.: (2003) Cytostatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes. Toxicol. Appl. Pharmacol. 192: 246–253.

Zídek, Z., Potměšil, P., Kmoníčková, E., Holý, A.: (2003) Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diamunopurines. Eur. J. Pharmacol. 475: 149–159.