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Antagonists of group I metabotropic glutamate receptors and cortical afterdischarges in immature rats.

MTEP, and antagonist of subtype mGluR5 of metabotropic glutamate receptors exhibits an anticonvulsant action in a model of cortical epileptic afterdischarges whereas AIDA, an antagonist of subtype mGluR1 does not.
Lojková-Janečková D, Ng J, Mareš P.: Antagonists of group I metabotropic glutamate receptors and cortical afterdischarges in immature rats. Epilepsia 2009; 50:2123-2129. IF=3.733
 

Author: lojkovabiomed.cas.cz

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