Supervisor
((Consultant))
Petr Štěpánek, DSc
TopicNanoparticles sensitive to external stimuli
AnnotationPolymeric nanoparticles have an increasing range of applications in many areas of nanotechnology and in functional systems for applications in medicine, biology and electronics. In this project we shall focus on the preparation of nanoparticles by physicochemical methods using synthesized precursors and their specific interactions with surface active materials (surfactants and block copoymers). This approach leads to the possibility of preparing nanoparticles using a wide variety of polymeric substances and therefore specifically tailored for a specific application such as targeted delivery of drugs or genetic material, or for diagnostic purposes. It is also possible to prepare nanoparticles that can be reversibly created and dissolved by action of external variables such as changes in temperature, pH, illumination, solvent composition or ionic strength. The nanoparticles and their reactions to environment will be studied by scattering of light and X-rays and by electron microscopy and atomic force microscopy.

Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410

Budova UMCH