From 26th April 2010 to 21st May 2010 in the Institute gallery of IMC AS CR, an exhibition Martin Janíček:Voice calligraphy takes place
77 PMM Conference Polymers in Medicine is to be held on 8.-12. July 2012.
74 PMM conference Contemporary Ways to Tailor-made Polymers: 18 - 22 July 2010
| Supervisor ((Consultant)) | Petr Štěpánek, DSc |
|---|---|
| Topic | New stimuli-responsive polymers and nanoparticles for biological applications |
| Annotation | Stimuli-responsive polymers showing a nonlinear response to an external signal have gained much interest as ‘‘smart’’ and advanced materials. Thermoresponsive polymers represent an important class, especially for biomedical applications, and in particular to research related to tumors that exhibit a higher temperature than normal body temperature. An example of a thermoresponsive polymer that is under-researched and under-utilized is that of polyoxazolines. These polymers are structurally closer to polypeptides than the often used N-isopropylacrylamide polymers. This project aims at the preparation, study of physicochemical properties and fine-tuning of structural properties of new thermoresponsive polymers, including (but not limited to) polyoxazolines and of their micelles and nanoparticles with respect to their use in biological applications, for example in the drug delivery field. For enhancing the biological applicability, thermoresponsive polymers and nanoparticles carrying a weak radionuclide can be prepared. Biological testing of the products will be done in cooperation with specialized biology laboratories. |
Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410
