From 26th April 2010 to 21st May 2010 in the Institute gallery of IMC AS CR, an exhibition Martin Janíček:Voice calligraphy takes place
77 PMM Conference Polymers in Medicine is to be held on 8.-12. July 2012.
74 PMM conference Contemporary Ways to Tailor-made Polymers: 18 - 22 July 2010
| Supervisor ((Consultant)) | Tomáš Etrych, PhD |
|---|---|
| Topic | High-molecular-weight biodegradable polymer carriers for drug targeting |
| Annotation | In the last two decades, water-soluble polymers became beneficial drug delivery systems suitable as carriers for anticancer agents, anti-inflammatory agents etc. Prefe-rably, the drugs are covalently bound to polymers via spacers, which enable controlled release of the active drug in treated tissues or cells. The thesis will focus on design, synthesis and study of physicochemical properties of high-molecular-weight biodegradable polymer anticancer drug delivery system intended for application in site-specific tumor therapy. Understanding of influence of conjugate structure on solution properties, controlled release of drug and biological properties (in collaboration with biological institutes) should facilitate design the structures of efficacious polymer cancerostatics. Applicant will work in the fields of organic chemistry, macromolecular chemistry and biochemistry and will use many techniques as HPLC, GPC, electrophoresis, etc. Cooperation with biological departments is also a part of this project. |
Institute of Macromolecular Chemistry AS CR, v.v.i.
Heyrovského nám. 2
CZ-162 06 Praha 6
Czech Republic
phone:+420 296 809 111
fax:+420 296 809 410
