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Education |
1989-1993 | Ph.D. in Biochemistry, at Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague. |
1983-1988 | M.Sc. in Biochemistry, at Charles University, Faculty of Natural Sciences, Prague. |
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Experience |
1998-1999 | Postdoctoral research associate, Lawrence Berkeley National Laboratory, Berkeley, California, U.S.A., Dr. T. Forte. |
1994-1996 | Postdoctoral research associate, Dept. Pharmacology, University of Sherbrooke, Canada, Prof. E. Escher. |
1991 (4 months) | Fellowship, Centre CNRS-INSERM de Pharmacologie et Endocrinologie, Montpellier, France, Prof. J. Martinez. |
1990 (1 month) | Fellowship, Institute of Organic Synthesis, Riga, Latvia, Prof.V.Kluša |
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Appointments |
since 2007 | Scientist, Jiracek's group, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague. |
2003-2006 | Scientist, Biological Chemistry Department, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague. |
2001-2003 | Maternity Leave. |
since 1993 | Researcher, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague. |
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Other Experience and Professional Memberships |
since 1996 | Member of European Peptide Society. |
since 2007 | Member of American Peptide Society. |
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Research interest |
- Structure-activity studies of peptides (cholecystokinin analogues, CART peptides) with special emphasis on their anorectic activity after central and peripheral administration; binding affinities, in vitro and in vivo functional assays.
- Study of food intake regulation in mouse models of obesity.
- Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).
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