Pejchar P., Pleskot R., Schwarzerová K., Jan Martinec J., Valentová O., Novotná Z.
CELL BIOLOGY INTERNATIONAL
32:
554-556,
2008
Keywords:
Aluminum toxicity; Phospholipase D; Microtubules
Abstract:
Aluminum is a highly cytotoxic metal to plants, but the molecular base and the primary target of Al toxicity are still unknown. The most
important physiological consequence of Al toxicity is a cessation of root growth and changes in root morphology suggesting a role of the
root cytoskeleton as a target structure. The important role of phospholipid degrading enzyme phospholipase D in regulation of cytoskeleton
remodelling in both animal and plant organisms is now evident. Both the phospholipid pathway and the cytoskeleton are influenced by
Al3+, but their relationship with Al stress remains to be explored. Therefore, we tested the possibility that Al stress could be sensed by plants
through microtubules in close interaction with phospholipases. We have shown that Al3+ reduced the formation of phosphatidic acid in vivo,
inhibited activity of phosphatidylinositol-4,5-bisphosphate-dependent phospholipase D in vitro and that the phosphatidic acid production is modified
by microtubule dynamics.
Fulltext: contact IEB authors
IEB authors: Jan Martinec,
Přemysl Pejchar
Čeština
English