Kokoška L., Janovská D., Rada V., Nepovím A., Vaněk T.
PHARMACEUTICAL BIOLOGY
43:
8-11 ,
2005
Klíčová slova:
Antibacterial activity; Leuzea; Rhaponticum
Abstrakt:
The crude ethanol extracts of the aerial parts and roots of Leuzea carthamoides DC., Leuzea centauroides (L.) Holub, Leuzea longifolia Hoffmgg. & Link, and Leuzea rhapontica subsp. bicknellii (Briq.) Holub have been investigated for their antibacterial activity. Growth inhibition using a broth tube dilution test was determined against Bacillus cereus Frankland and Frankland, Bacillus subtilis (Ehrenberg) Cohn, Bacteroides fragilis (Veillon and Zuber) Castellani and Chalmers, Enterococcus faecalis (Andrewes and Horder) Scheifer and Kilpper-Blz, Escherichia coli (Migula) Castellani and Chalmers, Pseudomonas aeruginosa (Schroeter) Migula, Staphylococcus aureus (Rosenbach), Staphylococcus epidermidis (Winslow and Winslow) Evans, Streptococcus pneumoniae (Klein) Chester, and Streptococcus pyogenes (Rosenbach). The results showed that extracts from aerial parts of all species tested exhibited significant antibacterial activity, especially against Bacillus cereus, Staphylococcus epidermidis and Bacteroides fragilis. In comparison with other Leuzea species, L. carthamoides was the most effective against the bacteria used in this study.
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