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Monoclonal antibodies available from the Laboratory
of molecular immunology
The specificities
of the mAbs
marked as (W) were verified by international HLDA workshops.
|
Antigen |
Antibody |
Isotype |
Note |
|
CD2 |
MEM-65
(W) |
IgG1 |
unique
epitope |
|
|
MEM-69 |
IgG1 |
|
|
CD3 (e) |
MEM-57
(W) |
IgG2a |
can be used clinically
(immunosuppression) |
|
|
MEM-92
(W) |
IgM |
activating |
|
CD4 |
MEM-16
(W) |
IgM |
epitope
in D1-D2 |
|
|
MEM-115
(W) |
IgG2a |
epitope
in D1; blocks gp120 |
|
|
MEM-241 |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-242 |
IgG1 |
weakly
positive in W. blotting (non-red.) |
|
CD5 |
MEM-32
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-128
(W) |
IgM |
|
|
|
MEM-247 |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD6 |
MEM-98 |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-100 |
IgG1 |
|
|
CD7 |
MEM-186
(W) |
IgG |
positive
in W. blotting (non-red.) |
|
CD8 |
MEM-31
(W) |
IgG2a |
|
|
|
MEM-87
(+ several others) |
IgG1 |
epitope
similar to MEM-31 |
|
|
MEM-146
(W) |
IgG1 |
epitope
different from MEM-31 |
|
CD9 |
MEM-62
(W) |
IgG1 |
|
|
|
MEM-192
(W) |
IgM |
positive
in W. blotting (non-red.) |
|
CD10 (CALLA) |
MEM-78
(W) |
IgG1 |
positive
in W. blotting (nen-red.) |
|
CD11a (LFA-1a) |
MEM-25
(W) |
IgG1 |
|
|
|
MEM-30
(W) |
IgG1 |
|
|
|
MEM-83
(W) |
IgG1 |
activates LFA-1 (to high affinity) |
|
|
MEM-94 |
IgG1 |
blocks
binding to ICAM-1 |
|
|
MEM-95
(W) |
IgG1 |
blocks
binding to ICAM-1 |
|
|
MEM-144 |
IgG1 |
|
|
|
MEM-152 |
IgG2b |
|
|
|
MEM-177 |
IgG1 |
epitope
similar to MEM-83 |
|
CD11b |
MEM-170
(W) |
IgG1 |
blocks
binding to ICAM-1 |
|
|
MEM-174
(W) |
IgG2a |
|
|
CD14 |
MEM-15
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-18
(W) |
IgG1 |
positive
in W. blotting (non-red.)
blocks binding of LPS-LBP to CD14 |
|
CD15 |
MEM-157 |
IgM |
|
|
|
MEM-158 |
IgM |
|
|
|
MEM-167 |
IgM |
|
|
CD16 |
MEM-154
(W) |
IgG1 |
positive
in W. blotting (non-red.)
recognizes a polymorphism
in CD16A (NK-form) |
|
|
MEM-168 |
IgM |
|
|
CD17 |
MEM-74 (W) (+ several others) |
IgM |
|
|
CD18 (LFA-1b) |
MEM-48 |
IgG1 |
positive
in W. blotting (non-red.)
induces high-affinity state of LFA-1 |
|
|
MEM-148 |
IgG1 |
unique
epitope accessible in free CD18 only;
activating mAb |
|
CD20 |
MEM-97
(W) |
IgG1 |
|
|
CD22b |
MEM-01 |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD25 |
MEM-140
(W) |
IgM |
|
|
|
MEM-141 |
IgM |
|
|
|
MEM-145
(W) |
IgM |
|
|
|
MEM-181
(W) |
IgG1 |
|
|
CD29 |
MEM-101A
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD30 |
MEM-268 |
IgG |
positive
in W. blotting (non-red.) |
|
CD31 |
MEM-05 |
IgG1 |
|
|
CD41 |
MEM-06 |
IgG1 |
|
|
CD43 |
MEM-59
(W) |
IgG1 |
sialic
acid-dependent epitope positive in W. blotting |
|
|
MEM-256 |
IgG1 |
positive
in W. blotting (non-red.); (atypical-epitope
absent in myeloid cells) |
|
|
MEM-257 |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD44 |
MEM-85
(W) |
IgG2b |
positive
in W. blotting (non-red.) |
|
|
MEM-263 |
IgG1 |
strongly positive in W. blotting |
|
CD45 |
MEM-28 (W) (+ several others) |
IgG1 |
positive
in W. blotting (red.,
non-red.)
positive in paraffin sections |
|
CD45RA |
MEM-56
(W) |
IgG2b |
positive
in W. blotting |
|
|
MEM-93
(W) |
IgG1 |
as
MEM-56 |
|
|
MEM-109 (+ several
others) |
IgG1 |
|
|
|
|
|
|
|
CD45RB |
MEM-55
(W) |
IgG1 |
carbohydrate-dependent epitope |
|
|
MEM-143 |
IgG1 |
|
|
CD46 |
MEM-258 |
IgG2a |
positive
in W. blotting (non-red.) |
|
CD47 |
MEM-122
(W) |
IgM |
|
|
|
MEM-120
(W) |
IgM |
low affinity |
|
|
MEM-133
(W) |
Ig2a |
low affinity |
|
CD48 |
MEM-102
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-124
(W) |
IgM |
|
|
|
MEM-200 |
IgG1 |
positive
in W. blotting |
|
|
MEM-201 |
IgG1 |
|
|
|
MEM-204 |
IgG3 |
|
|
|
MEM-211 |
IgG2b |
positive
in W. blotting |
|
|
MEM-212 |
IgG2b |
|
|
|
MEM-213 |
IgG1 |
|
|
CD50 |
MEM-04 |
IgG1 |
epitope
in D1; blocks DC-SIGN binding |
|
|
MEM-171
(W) |
IgG1 |
epitope
in D2 |
|
CD53 |
MEM-53
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD54 (ICAM-1) |
MEM-111(W) |
IgG2a |
positive
in W. blotting (non-red.) |
|
|
MEM-112
(W) |
IgG1 |
as
MEM-111 but weaker |
|
CD55 (DAF) |
MEM-118
(W) |
IgM |
|
|
CD56 |
MEM-188
(W) |
IgG2a |
positive
in W. blotting (non-red.) |
|
CD58 |
MEM-63
(W) |
IgG1 |
epitope
in D1 |
|
CD59 |
MEM-43
(W) |
IgG2a |
positive
in W. blotting (non-red.) |
|
|
MEM-43/5 (W) (+ several others) |
IgG2b |
different epitope; strong in W. blotting non-red.) |
|
|
MEM-125
(W) |
IgM |
|
|
|
MEM-129
|
IgM |
|
|
CD63 |
MEM-259 |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD71 (TfR) |
MEM-75
(W) |
IgG1 |
does
not block transferrin binding |
|
|
MEM-105 |
IgG2a |
does
not block transferrin binding |
|
|
MEM-189
(W) |
IgG1 |
positive
in W. blotting (non-red.) does
not block transferrin binding |
|
|
MEM-191 |
IgG |
does
not block transferrin binding |
|
CD80 |
MEM-233 |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-234 |
IgG1 |
positive
in W. blotting |
|
|
MEM-235 |
IgG1 |
positive
in W. blotting |
|
CD97 |
MEM-180
(W) |
IgG1 |
|
|
CD98 |
MEM-108
(W) |
IgG1 |
|
|
|
MEM-156
(W) |
IgM |
|
|
CD99R |
MEM-131
(W) |
IgM |
positive
in W. blotting |
|
CD105 |
MEM-223 (+ several
others) |
IgG |
positive
in W. blotting (non-red.) |
|
CD108 |
MEM-121
(W) |
IgM |
positive
in W. blotting |
|
|
MEM-150
(W) |
IgM |
as
MEM-121; higher affinity |
|
CD147 |
MEM-M6/1 (+ several
others) |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD148 |
MEM-CD148/01 MEM-CD148/5 |
IgG1 IgG2b |
positive
in W. blotting (non-red.) FACS |
|
CD173 |
MEM-195
(W) |
IgM |
|
|
|
MEM-196
(W) |
IgM |
|
|
|
MEM-197
(W) |
IgM |
|
|
|
MEM-198
(W) |
IgM |
|
|
CD177 |
MEM-166
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD222 |
MEM-238
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
|
MEM-239 |
IgG1 |
|
|
|
MEM-240
(W) |
IgG1 |
positive
in W. blotting (non-red.) |
|
CD300 |
MEM-260 |
IgG |
positive
in W. blotting (non-red.) |
|
|
|
|
|
|
b2 microglobulin |
B2M-01 |
IgG2a |
positive
in W. blotting (non-red.) |
|
|
B2M-02 |
IgG1 |
positive
in W. blotting (non-red.) |
|
HLA-DR |
MEM-12 (+ several
others) |
IgG1 |
in W. blotting recognizes only the ab dimer (non-boiled
sample) |
|
HLA-DR+DP (b-chain) |
MEM-136 |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
|
MEM-138 |
IgG2a |
positive
in W. blotting (non-red.;
red.) |
|
HLA-DR (a-chain) |
MEM-137 |
IgG1 |
positive
in W. blotting (non-red.) |
|
MHC class
II, human, mouse |
SLE-01,
-03, -04, -06 |
chicken IgY |
positive
in W. blotting |
|
|
|
|
|
|
HLA-class
I |
MEM-147 |
IgG1 |
reacts
in W. blotting (non-red.)
with some allelic forms; very similar to W6/32) |
|
HLA-class
I |
MEM-81 |
IgG1 |
|
|
|
MEM-119 |
IgM |
|
|
|
MEM-123 |
IgG3 |
|
|
|
MEM-130 |
IgM |
|
|
|
MEM-149 |
IgG1 |
reacts
with an undefined polymorphic determinant (present
in most subjects) |
|
|
MEM-155 |
IgG1 |
|
|
HLA-E |
MEM-E/2 (+ several
others) |
IgG |
positive
in W. blotting (does not react with native
molecule) |
|
|
MEM-E/6,
E/7, E/8 |
IgG1 |
react
with partially denatured molecule, cross-reactive with some other MHC class I molecules |
|
HLA-G |
MEM-G/1 (+ several
others) |
IgG1 |
positive
in W. blotting and paraffin
sections (does not react with native molecule) |
|
|
MEM-G/9 (+ several
others) |
IgG1 |
reacts
with native molecule |
|
Ig k-chains |
MEM-09 |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
|
MEM-40 |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
TCR-Vb5-related
(HPB-ALL) |
MEM-262 |
IgG2a |
positive
in W. blotting (non-red.;
red.) |
|
Insulin (human,
pig, bovine) |
IN-05 |
IgG1 |
|
|
|
IN-06 |
IgG2b |
|
|
C-peptide of
human proinsulin |
C-PEP-01 |
IgG1 |
|
|
a-fetoprotein (human) |
AFP-01,
02, 03 -11,-12,-13,-14 |
all
IgG1 |
different epitopes |
|
Glutamate carboxypeptidase II (GCPII) |
GCP-01,
02, 04 GCP-05 |
all
IgG1 |
positive
in W. blotting (GCP-02) native
protein, for IP |
|
Phosphotyrosine |
P-TYR-01 |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
|
P-TYR-02 |
IgG2b |
positive
in W. blotting (non-red.;
red.) |
|
Lck (human) |
LCK-01 (peptide 22-36) |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
Lck (human, mouse) |
LCK-04 (peptide 22-36) |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
|
FYN-01 (fragment aa7-197) |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
Csk (human, mouse) |
CSK-04
(fragment aa330-450) |
IgG1 |
positive
in W. blotting (non-red.;
red.) |
|
SLP-76 (human) |
SLP-76/1 |
IgG1 |
Positive
in W. blotting (weak) |
|
ZAP-70 |
ZAP-70/2 |
IgG1 |
Positive
in W. blotting |
|
SKAP-HOM (human
and mouse) |
SKAP-HOM-01,
02, 03 |
IgG |
Positive
in W. blotting, human, mouse |
|
|
|
|
|
|
TRAIL |
TRAIL-01 (+ several
others) |
IgG |
positive
in W. blotting; some mAbs blocking |
|
TRIM |
TRIM-01
through TRIM-10 |
IgG2a |
some
positive in W. blotting, some
reactive also with mouse |
|
SIT |
SIT-01
through SIT-04 |
IgG |
some
positive in W. blotting, some
reactive also with mouse |
|
Daxx |
DAXX-01
through DAXX-04 |
IgG |
positive
in W. blotting |
|
PAG |
MEM-253 |
IgG2a |
weak
in W. blotting; for IP |
|
|
MEM-255 |
IgG2a |
positive
in W. blotting |
|
|
PAG-C1 |
IgG2b |
C-terminal peptide; human, mouse PAG |
|
|
PAG-C6 |
IgG2b |
C-terminal peptide; human, mouse PAG |
|
NTAL |
NAP-3 |
IgG2a |
Anti-peptide; positive in W. blotting |
|
|
NAP-7 |
IgG1 |
Positive
in W. blotting (human, mouse) |
|
|
NAP-8 |
IgG1 |
Positive
in W. blotting (human, mouse) |
|
LAT |
LAT-01 |
IgG1 |
Positive
in W. blotting; poor with phosphorylated LAT |
|
LIME |
LIME-10
(and several others) |
IgG2a |
Positive
in W. blotting |
|
Mouse LIME |
mLIME-05
(and several others) |
IgG2a |
Positive
in W. blotting |
|
EBP50 (NHERF) |
EBP-10 |
IgG2b |
Positive
in W. blotting |
|
Evi2b |
MEM-216 |
IgG1 |
Positive
in W. blotting |
|
Sos1 |
SOS-01 |
IgG1 |
Anti-peptide,
Positive in WB |
|
H-Ras |
H-RAS-01 |
IgG1 |
Anti-peptide, Positive in WB |
|
GCPII (PSMA) |
GCPII-04 GCPII-05 |
IgG1 IgG1 |
Positive
in WB Native
molecule, IP |
|
GCPIII |
GCPIII-02 |
IgG1 |
Positive
in WB |
|
PSMA-L (naaldase-L) |
PSMA-L/01 |
IgG2b |
Positive
in WB |
|
SHIP-1 |
SHIP-01 |
IgG2a |
Anti-peptide,
Positive in WB |
|
DNA helicase II (KuII) |
MEM-54 |
IgG2a |
|
|
LST1/A |
LST1-2 |
IgG1 |
Anti-peptide,
Positive in WB |
|
Lamin A/B |
LST1-1 |
IgG2a |
Positive
in WB, crossreactive with
LST1/A (useful for lamin especially in non-myeloid cells, negative for LST1/A) |
|
Nvl |
NVL-03 (and several others) |
IgG1 |
Positive
in WB |
|
Drebrin |
DBN-N-01 (and several others) |
IgG2a |
Positive
in WB |
|
CLIC5 |
CLIC5-01
(and
several others) |
IgG1 |
Anti-peptide,
Positive in WB |
|
OPAL1 |
OPAL1-01, 02 |
G2a |
Positive
in WB |
|
TFG |
TFG-01, 02, 03 |
G2b |
Positive
in WB |
|
LARGE |
LARGE 01 (and several
others) |
G2a |
Positive
in WB |
|
|
|
|
|
|
|
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