31. 3. 1980 in Bratislava (Slovak Republic).
, M. S. degree - specialization organic chemistry (supervisor Ing. Jedlovská)
(supervisor Dr. M. Hocek)
11. |
Šilhár, P.; Hocek, M.; Pohl, R.; Votruba, I.; Shih, I.; Mabery, E.; Mackman, R.: "Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides" Bioorg. Med. Chem. 2008, 16, 2329-2366. |
10. |
Hasník, Z.; Šilhár, P.; Hocek, M.: "Hydroxymethylations of Aryl Halides by Pd-Catalyzed Cross-Couplings with (Benzoyloxy)methylzinc Iodide – Scope and Limitations of the Reaction" Synlett 2008, 543–546. |
9. |
Hasník, Z.; Šilhár, P.; Hocek, M.: "Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent" Tetrahedron Lett. 2007, 48, 5589–5592. |
8. |
Hocek, M.; Šilhár, P.: "Palladium-Catalyzed Cross-Coupling Reactions in C6 Modifications of Purine Nucleosides" Curr. Protocols Nucleic Acid Chem. (J. Wiley & Sons., Inc.) 2007, 1.16. |
7. |
Hocek, M.; Šilhár, P.; Pohl, R.: "Cytostatic and activiral 6-arylpurine ribonucleosides VIII. Synthesis and evaluation of 6-substituted purine 3'-deoxyribonucletides" Collect. Czech. Chem. Commun. 2006, 71, 1484-1496. |
6. |
Hocek, M.; Šilhár, P.; Shih, I.; Mabery, E.; Mackman, R.: "Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine L-ribonucleosides" Bioorg. Med. Chem. Lett. 2006, 16, 5290–5293. |
5. |
Šilhár, P.; Pohl, R.; Votruba, I.; Klepetářová, B.; Hocek, M.: "Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl- 2-(Hydroxymethyl)purine Bases and Nucleosides" Collect. Czech. Chem. Commun. 2006, 71, 788-803. |
4. |
Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: "Synthesis and Cytostatic Activity of Novel 6-(Difluoromethyl)purine Bases and Nucleosides" Synthesis 2006, 1848-1852. |
3. |
Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: "Synthesis of 2-Substituted 6-(Hydroxymethyl)Purine Bases and Nucleosides" Collect. Czech. Chem. Commun. 2005, 70, 1669-1695. |
2. |
Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: "The First Synthesis and Cytostatic Activity of Novel 6-(Fluoromethyl)purine Bases and Nucleosides" Org. Biomol. Chem. 2005, 3, 3001-3007. |
1. |
Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: "Facile and Efficient Synthesis of 6-(Hydroxymethyl)purines" Org. Lett. 2004, 6, 3225-3228. |