Supramolecular materials based on natural phytosterols for application in biology

Duration: 
01.07.2006 - 30.06.2011
Classification
Grant agency: 
MŠMT
Grant type: 
Standardní projekt
Registration number: 
2B06024
Investigators
Internal investigator/coinvestigator: 
Helena Sovová
Internal investigator: 
is principal investigator
Annotation: 

The project is focused on:

(a) Designing a new approach for effective working-up of cultural plants by non-traditional ways with focusing on extraction of phytosteroids and phytosterols from model plant material by using supercritical carbon dioxide;

(b) Designing a synthesis of several types of supramolecules on the basis of naturally occurring (biodegradable) phytosteroids for application in biology, through which approach an added value will be given to the plant material in consequence with using extracted natural products in new types of supramolecular materials for application in biology and medicine;

(c) Designing a synthesis of model supramolecular biologically active compounds (juvenogens), in which selected compounds displaying biological activity on insect will be used as model system;

(d) Performing biological screening tests of model supramolecular juvenogens on selected insect species, namely on aphids (Acyrthosiphon pisum), bugs (Pyrrhocoris apterus), and two types of termites. 2B06024