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Významné publikace


Vybrané významnější publikace, u nichž je alespoň první nebo korespondující autor zaměstnancem Ústavu molekulární genetiky
(jména všech zaměstnanců ÚMG jsou podtržena)


   2011
Draber, P. - Vonkova, I. - Stepanek, O. - Hrdinka, M. - Kucova, M. - Skopcova, T. - Otahal, P. - Angelisova, P. - Horejsi, V. - Yeung, M. - Weiss, A. - Brdicka, T.
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Molecular and Cellular Biology31(22): 4550-62 (2011). PubMed
Hájková, Z.Bugajev, V. - Dráberová, E. - Vinopal, S. - Dráberová, L. - Janáček, J. - Dráber, P. - Dráber, P.
STIM1-Directed Reorganization of Microtubules in Activated Mast Cells.
Journal of Immunology, 186(2): 913-923 (2011). PubMed
Holan, V. - Chudickova, M. - Trosan, P. - Svobodova, E. - Krulova, M. - Kubinova, S. - Sykova, E. - Sirc, J. - Michalek, J. - Juklickova, M. - Munzarova, M. - Zajicova, A.
Cyclosporine A-loaded and stem cell-seeded electrospun nanofibers for cell-based therapy and local immunosuppression.
Journal of Controlled Release156(3):406-12 (2011). PubMed
Hrdinka, M. - Dráber, P. - Stepánek, O. - Ormsby, T. - Otáhal, P. - Angelisová, P. - Brdicka, T. - Paces, J. - Horejsí, V. - Drbal, K.
PRR7 Is a Transmembrane Adaptor Protein Expressed in Activated T Cells Involved in Regulation of T Cell Receptor Signaling and Apoptosis.
Journal of  Biological  Chemistry286(22): 19617-29 (2011). PubMed
Mader, P. - Brynda, J. - Gitto, R. - Agnello, S. - Pachl, P. - Supuran, C.T. - Chimirri, A. - Řezáčová, P.
Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides.
Journal of Medicinal Chemistry54(7): 2522-2526 (2011). PubMed
Novotný, I. - Blažíková, M. - Staněk, D. - Heřman, P. - Malínský, J.
In vivo kinetics of U4/U6.U5 tri-snRNP formation in Cajal bodies.
Molecular Biology of the Cell22(4): 513-523 (2011). PubMed
Ormsby, T. - Schlecker, E. - Ferdin, J. - Tessarz, A.S. - Angelisová, P. - Köprülü, A.D. - Borte, M. - Warnatz, K. - Schulze, I. - Ellmeier, W. - Horejsí, V. - Cerwenka, A.
Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.
Blood118(4): 936-45 (2011). PubMed
Stachura, D.L. - Svoboda, O. - Lau, R.P. - Balla, K.M. - Zon, L.I. - Bartunek, P. - Traver, D.
Clonal analysis of hematopoietic progenitor cells in the zebrafish.
Blood118(5): 1274-82 (2011). PubMed
Stepanek, O. - Kalina, T. - Draber, P. - Skopcova, T. - Svojgr, K. - Angelisova, P. - Horejsi, V. - Weiss, A. - Brdicka, T.
Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148.
Journal of Biological  Chemistry286(25): 22101-22112 (2011). PubMed
Strnad, H. - Rídl, J. - Pačes, J. - Kolář, M. - Vlček, Č. - Pačes, V.
Complete genome sequence of the haloaromatic acid-degrading bacterium Achromobacter xylosoxidans A8.
Journal of Bacteriology193(3): 791-792 (2011). PubMed
Vlček, Č. - Marande, W. - Teijeiro, S. - Lukeš, J. - Burger, G.
Systematically fragmented genes in a multipartite mitochondrial genome.
Nucleic Acids Research39(3): 979-988 (2011). PubMed
Trejbalová, K. - Blazková, J. - Matousková, M. - Kucerová, D. - Pecnová, L. - Vernerová, Z. - Herácek, J. - Hirsch, I. - Hejnar, J.
Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin.
Nucleic Acids Research, 39(20): 8728-39 (2011). PubMed

   2010
Huranová, M. - Ivani, I. - Benda, A. - Poser, I. - Brody, Y. - Hof, M. - Shav-Tal, Y. - Neugebauer, K.M. - Stanek, D.
The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells.
J Cell Biol.191(1): 75-86 (2010). PubMed
Bartek, J. - Hodny, Z.
SUMO Boosts the DNA Damage Response Barrier against Cancer.
Cancer Cell, 17(1): 9-11 (2010). PubMed
Blazkova, H. - Krejcikova, K. - Moudry, P. - Frisan, T. - Hodny, Z. - Bartek, J.
Bacterial Intoxication Evokes Cellular Senescence with Persistent DNA Damage and Cytokine Signaling.
J Cell Mol Med., 14(1-2): 357-67 (2010). PubMed
Heneberg, P. - Dráberová, L. - Bambousková, M. - Pompach, P. - Dráber P.
Down-regulation of protein tyrosine phosphatases activates an immune receptor in the absence of its translocation into lipid rafts.
J Biol Chem.285(17): 12787-802 (2010). PubMed
Holáň, V. - Pokorná, K. - Procházková, J. - Krulová, M. - Zajícová, A.
Immunoregulatory  properties of mouse limbal stem cells.
J Immunol., 184(4): 2124-9 (2010) PubMed
Zajícová, A. - Pokorná, K. - Lenčová, A. - Krulová, M. - Svobodová, E. - Kubínová, Š. - Syková, E. - Přádný, M. - Michálek, J. - Svobodová, J. - Munzarová, M. - Holáň, V.
Treatment of ocular surface injuries by limbal and mesenchymal stem cells growing on nanofiber scaffolds.
Cell Transplant. 2010 Jun 23. PubMed
Furugaki, K. - Pokorna, K. - le Pogam, C. - Aoki, M. - Reboul, M. - Bajzik, V. - Krief, P. - Janin, A. - Noguera, M.-E. - West, R. - Charron, D. - Chomienne, C. - Pla, M. -  Moins-Teisserenc, H. - Padua, R A.
DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model.
Blood, 115(3): 653-6 (2010). PubMed
Kanagaraj, R. - Huehn, D. - Mackellar, A. - Menigatti, M. - Zheng, L. - Urban, V. - Shevelev, I. - Greenleaf, A.L. - Janscak, P.
RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription.
Nucleic Acids Res. 2010 Aug 12. PubMed
Kobets, T. - Badalová, J. - Grekov, I. - Havelková, H. - Svobodová, M.Lipoldová, M.
Leishmania parasite detection and quantification using PCR-ELISA.
Nat Protoc., 5(6): 1074-80 (2010). PubMed
Králová, J. - Kejík, Z. - Bríza, T. - Poucková, P. - Král, A. - Martásek, P. - Král V.
Porphyrin-cyclodextrin conjugates as a nanosystem for versatile drug delivery and multimodal cancer therapy.
J Med Chem., 53(1): 128-38 (2010). PubMed
Kralova, J. - Sheely, J.I. - Liss, A.S. - Bose, H.R. Jr.
ERK and JNK activation is essential for oncogenic transformation by v-Rel.
Oncogene, 2010 Aug 30. PubMed
Ma, J. - Flemr, M. - Stein, P. - Berninger, P. - Malik, R. - Zavolan, M. - Svoboda, P. - Schultz R.M.
MicroRNA Activity Is Suppressed in Mouse Oocytes.
Curr Biol., 20(3): 265-70 (2010). PubMed
Macurek, L. - Lindqvist, A. - Voets, O. - Kool, J. - Vos, H.R. - Medema, R. H.
Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition.
Oncogene, 29(15): 2281-91 (2010). PubMed
Novakova, Z. - Hubackova, S. - Kosar, M. - Janderova-Rossmeislova, L. - Dobrovolna, J. - Vasicova, P. - Vancurova, M. - Horejsi, Z. - Hozak, P. - Bartek, J. - Hodny Z.
Cytokine expression and signaling in drug-induced cellular senescence.
Oncogene, 29(2): 273-84 (2010). PubMed
Otáhal, P. - Angelisová, P. - Hrdinka, M. - Brdicka, T. - Novák, P. - Drbal, K. - Horejsí V.
A new type of membrane raft-like microdomains and their possible involvement in TCR signaling.
J Immunol., 184(7): 3689-96 (2010). PubMed
Plachý, J. - Kotáb, J. - Divina, P. - Reinišová, M. - Šenigl, F. - Hejnar J.
Proviruses selected for high and stable expression of transduced genes accumulate in broadly transcribed genome areas.
J Virol., 84(9): 4204-11 (2010). PubMed
Schwendener, S. - Raynard, S. - Paliwal, S. - Cheng, A. - Kanagaraj, R. - Shevelev, I. - Stark, J. M. - Sung, P. - Janscak P.
Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity.
J Biol Chem.285(21): 15739-45 (2010). PubMed
Sedlak, D. - Novak, P. - Kotora, M. - Bartunek, P.
Synthesis and evaluation of 17alpha-arylestradiols as ligands for estrogen receptor alpha and beta.
J Med Chem.53(10): 4290-4 (2010). PubMed
Símová, J. - Indrová, M.Bieblová, J. - Mikysková, R. - Bubeník, J. - Reinis, M.
Therapy for minimal residual tumor disease: beta-galactosylceramide inhibits the growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy.
Int J Cancer.126(12): 2997-3004 (2010). PubMed
Svoboda, P.Flemr, M.
The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency.
EMBO Rep., 11(8): 590-7 (2010). PubMed

   2009
Mihola, O.Trachtulec, Z.Vlček, C. - Schimenti, J.C. - Forejt, J.
Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase.
Science323(5912): 373-5 (2009). PubMed
Huranova, M. - Hnilicova, J. - Fleischer, B. - Cvackova, Z. - Stanek D.
A mutation linked to retinitis pigmentosa in HPRP31 causes protein instability and impairs its interactions with spliceosomal snRNPs.
Hum Mol Genet.18(11): 2014-23 (2009). Epub 2009 Mar 17. PubMed
Zheng, L. - Kanagaraj, R. - Mihaljevic, B. - Schwendener, S. - Sartori, A.A. - Gerrits, B. - Shevelev, I. - Janscak, P.
MRE11 complex links RECQ5 helicase to sites of DNA damage.
Nucleic Acids Res.37(8): 2645-57 (2009). Epub 2009 Mar 6. PubMed
Lukas, J. - Mazna, P. - Valenta, T. - Doubravska, L. - Pospichalova, V. - Vojtechova, M. - Fafilek, B. - Ivanek, R. - Plachy, J. - Novak, J. - Korinek, V.
Dazap2 modulates transcription driven by the Wnt effector TCF-4.
Nucleic Acids Res., 37(9): 3007-20 (2009). Epub 2009 Mar 20. PubMed
Pajer, P. - Karafiat, V. - Pecenka, V. - Prukova, D. - Dudlova, J. - Plachy, J. - Kasparova, P. - Dvorak M.
Industasis, a promotion of tumor formation by nontumorigenic stray cells.
Cancer Res.69(11): 4605-12 (2009). PubMed
Blazkova, J. - Trejbalova, K. - Gondois-Rey, F. - Halfon, P. - Philibert, P. - Guiguen, A. - Verdin, E. - Olive, D. - Van Lint, C. - Hejnar, J. - Hirsch, I.
CpG methylation controls reactivation of HIV from latency.
PloS Pathog., 5(8): e1000554 (2009). Epub 2009 Aug 21. PubMed

   2008
Svoboda, P.
RNA silencing in mammalian oocytes and early embryos.
Curr Top Microbiol Immunol.320:225-256 (2008). PubMed
Bartek, J. - Hodny, Z. - Lukas, J.
Cytokine loops driving senescence.
Nat Cell Biol., 10: 887-889 (2008). PubMed
Bubenik J.
Genetically modified cellular vaccines for therapy of human papilloma virus type 16 (HPV 16)-associated tumours.
Curr Cancer Drug Targets, 8: 180-186 (2008). PubMed
Stanek, D. - Pridalová-Hnilicova, J. - Novotny, I. - Huranova, M. - Blazikova, M. - Wen, X. - Sapra, A.K. - Neugebauer, K.M.
Spliceosomal small nuclear ribonucleoprotein particles repeatedly cycle through Cajal bodies.
Mol Biol Cell., 19: 2534-2543 (2008). PubMed
Kozmik, Z. - Ruzickova, J. - Jonasova, K. - Matsumoto, Y. - Vopalensky, P. - Kozmikova, I. - Strnad, H. - Kawamura, S. - Piatigorsky, J. - Paces, V. - Vlcek, C.
Assembly of the cnidarian camera-type eye from vertebrate-like components.
Proc Natl Acad Sci USA,  105(26): 8989-8993 (2008). PubMed
Sinkkonen, L. - Hugenschmidt, T. - Berninger, P. - Gaidatzis, D. - Mohn, F. - Artus-Revel, C.G. - Zavolan, M. - Svoboda, P.* - Filipowicz, W.*
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells.
Nat Struct Mol Biol., 15(3): 259-67 (2008). PubMed
Gregorová, S. - Divina, P.Storchová, R. - Trachtulec, Z. - Fotopulosová, V. - Svenson, K.L. - Donahue, L.R. - Paigen, B. - Forejt J.
Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies.
Genome Res., 18: 509-515 (2008). PubMed

   2007
Vlasakova, J. - Novakova, Z. - Rossmeislova, L. - Kahle, M. - Hozak, P. - Hodny, Z.
Histone deacetylase inhibitors suppress IFNalpha-induced up-regulation of promyelocytic leukemia protein.
Blood, 109: 1373-80 (2007). PubMed
Sojka, L. - Fučík, V. - Krásný, L. - Barvík, I. - Jonák, J.
YbxF – a protein associated with exponential phase ribosomes in Bacillus subtilis.
J. Bacteriol. 189: 4809-14 (2007). PubMed
Homolka, D. - Ivanek, R. - Capkova, J. - Jansa, P. - Forejt, J.
Chromosomal rearrangement interferes with meiotic X chromosome inactivation.
Genome Res., 17: 1431-7 (2007). PubMed
Smrz, D. - Draberova, L. - Draber, P.
Non-apoptotic phosphatidylserine externalization induced by engagement of glycosylphosphatidylinositol-anchored proteins.
J. Biol. Chem., 282: 10487-97 (2007). PubMed
Fujimura, N. - Vacik, T. - Machon, O. - Vlcek, C. - Scalabrin, S. - Speth, M. - Diep, D. - Krauss, S. - Kozmik, Z.
Wnt-mediated downregulation of Sp1 target genes by a transcriptional repressor Sp5.
J. Biol. Chem., 282 [20]: 1225-1237 (2007). PubMed

   2006
Reinis M. - Simova J. - Bubenik J.
Inhibitory effects of unmethylated CpG oligodeoxynucleotides on MHC vlase I-deficient and -proficient HPV16-associated tumours.
Int. J. Cancer, 118 1836-1842 (2006). PubMed
Matoušková, M. - Blažková, J. - Pajer, P. - Pavlíček, A. - Hejnar, J.
CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues. Exp. Cell Res., 312 [7] 1011-1020 (2006). PubMed
Lipoldova, M. - Demant, P. 
Genetic susceptibility to infectious disease: lessons from mouse models of leishmaniasis.
Nat. Rev. Genet., 7 [4] 294-305 (2006). PubMed
Štokrová, J. - Šloncová, E. - Sovová, V. - Kučerová, D. - Žíla, V. - Turečková, J. - Vojtěchová, M. - Korb, J. - Tuháčková Z.
Characterization of four clones derived from human adenocarcinoma cell line, HT29, and analysis of their response to sodium butyrate.
Int. J. Oncol., 28 559-565 (2006). PubMed
Heneberg, P. - Lebduška, P. - Dráberová, L. - Korb, J. - Dráber, P.
Topography of plasma membrane microdomains and its consequences for mast cell signaling.
Eur. J. Immunol., 36 2795-2806 (2006). PubMed  
Koc, M. - Naďová, Z. - Kovář, J.
Sensitivity of cells to apoptosis induced by iron deprivation can be reversibly changed by iron availability.
Cell Prolif., 39 [6] 551-561 (2006). PubMed
Asahina, M. - Valenta, T. - Šilhánková, M. - Kořínek, V. - Jindra, M.:
Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad.
Dev. Cell, 11 [2] 203-211 (2006). PubMed
Valenta, T. - Lukáš, J. - Doubravská, L. - Fafílek, B. - Kořínek, V.
HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.
EMBO J., 25 [11] 2326-2337 (2006). PubMed
Tedoldi, S. - Paterson, J.C. - Hansmann, M.L. - Natkunam, Y. - Ruediger, T. - Angelisová, P. - Du, M.Q. - Roberton, H. - Roncador, G. - Sanchez, L. - Pozzobon, M. - Masir, N. - Barry, R. - Pileri, S. - Mason, D.Y. - Marafioti, T. - Hořejší, V.
Transmembrane adaptor molecules: a new category of lymphoid-cell markers.
Blood, 107 213-221 (2006). PubMed 
Katsetos, C.D. - Reddy, G. - Dráberová, E. - Šmejkalová, B. - Del Valle, L. - Ashraf, Q. - Tadevosyan, A. - Yelin, K. - Maraziotis, T. - Mishra, O.P. - Mörk, S. - Legido, A. - Nissanov, J. - Baas, P.W. - de Chadarévian, J.P. - Dráber, P.
Altered cellular distribution and subcellular sorting of γ-tubulin in diffuse astrocytic gliomas and human glioblastoma cell lines suggest centrosome protein amplification.
J. Neuropathol. Exp. Neurol., 65 465-477 (2006). PubMed
Sulimenko, V. - Dráberová, E. - Sulimenko, T. - Macůrek, L. - Richterová, V. - Dráber, Pe. - Dráber, P.
Regulation of microtubule formation in activated mast cells by complexes of γ-tubulin with Fyn and Syk kinases.
J. Immunol., 176 7243-7253 (2006). PubMed
Pavlíček, A. - Gentles, A.J. - Pačes, J. - Pačes, V. - Jurka, J.
Retroposition of processed pseudogenes: the impact of RNA stability and translational control.
Trends Genet, 22 [2] 69-73 (2006). PubMed
Pajer, P. - Pečenka, V. - Králová, J. - Karafiát, V. - Průková, D. - Zemanová, Z. - Kodet, R. - Dvořák, M.
Identification of Potential Human Oncogenes by Mapping the Common Viral Integration Sites in Avian Nephroblastoma.
Cancer Res, 66 [1] 78- 86 (2006). PubMed

   2005
Bartková, J. -  Hořejší, Z. - Koed, K. - Kramer, A. - Tort, F. - Zieger, K. - Guldberg, P. - Sehested, M. - Nesland, J.M. - Lukas, C. - Orntoft, T. - Lukas, J. - Bartek, J.
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Nature, 434 [7035] 864-870 (2005). PubMed
Brdička, T. -  Kadleček, T.A. - Roose, J.P. - Pastuszak, A.W. - Weiss, A.
Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases.
Mol. Cell Biol., 25 [12] 4924-33 (2005). PubMed
Cígler P. - Kožíšek M. - Řezáčová P. - Brynda J. - Otwinowski Z. - Pokorná J. - Plešek J. - Grüner B. - Dolečková-Marešová L. - Máša M. - Sedláček J. - Bodem J. - Kraeusslich H.-G. - Král V. - Konvalinka J.
From non-peptide towards non-carbon protease inhibitors: metallacarboranes as specific and potent inhibitors of HIV protease.
Proc. Natl. Acad. Sci. U.S.A., 102 [43] 15394-9 (2005). PubMed
Divina, P. - Vlcek, C. - Strnad, P. - Paces, V. - Forejt, J.
Global transcriptome analysis of the C57BL/6J mouse testis by SAGE: evidence for nonrandom gene order.
BMC Genomics, 6 [1] 29 (2005). PubMed
Dráber, P. - Dráberová, L.
Lifting the fog in store-operated Ca2+ entry.
Trends Immunol., 26 [12] 621-624 (2005). PubMed
Drosopoulos, K.G. - Roberts,M.L. - Cermak, L. - Sasazuki, T. - Shirasawa, S. - Andera, L. - Pintzas, A.
Transformation by Oncogenic RAS Sensitizes Human Colon Cells to TRAIL-induced Apoptosis by Up-regulating Death Receptor 4 and Death Receptor 5 through a MEK-dependent Pathway.
J. Biol. Chem., 280 [24] 22856-22867 (2005). PubMed
Elleder, D. - Stepanets, V. - Melder, D.C. - Šenigl, F. - Geryk, J. - Pajer, P. - Plachý, J. - Hejnar, J. - Svoboda, J.
Federspiel, M.J.: The receptor for the subgroup C avian sarcoma and leukosis viruses, Tvc, is related to mammalian butyrophilins, members of the immunoglobulin superfamily.
J. Virol., 79 [16] 10408-10419 (2005). PubMed
Grinchuk., O. - Kozmik, Z. - Wu, X. - Tomarev, S.
The Optimedin gene is a downstream target of Pax6.
J Biol Chem., 280 [42] 35228-37 (2005). PubMed
Jansa, P. - Divina, P. - Forejt, J.
Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain).
BMC Genomics, 6 [-] 161 (2005). PubMed
Kaspar, P. - Pajer, P. - Sedlak, D. - Tamaoki, T. - Dvorak, M.
c-Myb inhibits myogenic differentiation through repression of MyoD.
Exp Cell Res, 309 [2] 419-428 (2005). PubMed
Koc, M. - Nad'ova, Z. - Truksa, J. - Ehrlichova, M. - Kovar, J.
Iron deprivation induces apoptosis via mitochondrial changes related to Bax translocation.
Apoptosis, 10 [2] 381-93 (2005). PubMed
Kozmik, Z.
Pax genes in eye development and evolution. PubMed
Curr Opin Genet Dev., 15 [4] 430-8 (2005)
Lipoldová, M. - Havelková, H. - Badalová, J. - Demant P.
Novel loci controlling lymphocyte proliferative response to cytokines and their clustering with loci controlling autoimmune reactions, macrophage functions, and lung tumor susceptibility.
Int. J. Cancer, 114 [3] 394-399 (2005). PubMed
Vacík, T. - Ort, M. - Gregorová, S. - Strnad, P. - Blatný, R. - Conte, N. - Bradley, A. - Bureš, J. - Forejt. J.
Segmental trisomy of chromosome 17 – a mouse model of human aneuploidy syndromes.
Proc. Natl. Acad. Sci. U.S.A., 102 [12] 4500-4505 (2005). PubMed
Wang, Y. - Horváth, O. - Hamm-Baarke, A. - Richelme, M. - Gregoire, C. - Guinamard, R. - Hořejší, V. - Angelisová, P. - Špička, J. - Schraven, B. - Malissen, B. - Malissen, M.
Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function.
Mol. Cell Biol., 25 [11] 4455-65 (2005). PubMed

   2004

Brynda, J. - Řezáčová, P. - Fábry, M. - Hořejší, M. - Štouračová, R. - Sedláček, J. - Souček, M. - Hradílek, M. - Lepšík, M. - Konvalinka, J.
A Phenylnorstatine Inhibitor Binding to HIV-1 Protease: Geometry, Protonation, and Subsite-Pocket Interactions Analyzed at Atomic Resolution.
Journal of Medicinal Chemistry, 47 [8] 2030-2036 (2004).  PubMed

Divina, P. - Forejt, J.
The Mouse SAGE Site: database of public mouse SAGE libraries.
Nucleic Acids Research, 32, [-] D482-D483 (2004). PubMed

Dráberová, L. - Lebduška, P. - Hálová, I. - Tolar, P. - Štokrová, J. - Tolarová, H. - Korb, J. - Dráber, P.
Signaling assemblies formed in mast cells activated via Fce receptor I dimers.
European Journal of Immunology, 34 [8] 2209-2219 (2004). PubMed

Drábková, L. - Kirschner, J. - Vlček, Č. - Pačes, V.
TrnL-trnF intergenetic spacer and trnL intron define major clades within Luzula and Juncus (Juncaceae): Importance of structural mutations.
Journal of Molecular Evolution, 59, [-] 1-10 (2004). PubMed

Elleder, D. - Melder, D. C. - Trejbalová, K. - Svoboda, J. - Federspiel, M.
Two different molecular defects in the Tva receptor gene explain the resistance to two tvar lines of chickens to infection by subgroup A avian sarcoma and leukosis viruses.
Journal of Virology, 78 [24] 13489-13500 (2004). PubMed

Hořejší, V. - Zhang, W. - Schraven, B.
Transmembrane adaptor proteins: organizers of immunoreceptor signalling.
Nature Reviews Immunology, 4 [8] 603-616 (2004). PubMed

Krásný, L. - Gourse, R. L.
An alternative strategy for bacterial ribosome synthesis: Bacillus subtilis rRNA transcription regulation.
EMBO Journal, 23 [22] 4473-4483 (2004). PubMed

Kukharskyy, V. - Sulimenko, V. - Macůrek, L. - Sulimenko, T. - Dráberová, E. - Dráber, P.
Complexes of gamma-tubulin with nonreceptor protein tyrosine kinases Src and Fyn in differentiating P19 embryonal carcinoma cells.
Experimental Cell Research, 298, [-] 218-228 (2004). PubMed

Lusková, P. - Dráber, P.
Modulation of the Fcepsilon receptor I signaling by tyrosine kinase inhibitors: search for therapeutic targets of inflammatory and allergy diseases.
Current Pharmaceutical Design, 10 [15] 1727-1736 (2004). PubMed

Libusová, L. - Sulimenko, T. - Sulimenko, V. - Hozák, P. - Dráber, P.
Gamma-tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms.
Experimental Ccell Research, 295, [-] 375-386 (2004). PubMed

Malý, P. - Marková, V. - Škopková, Z. - Jeníková, G. - Kalaninová, J. - Láchová, J.
Molecular cloning, tissue distribution and construction of recombinant forms of the mouse galectin-4 and galectin-6.
Glycobiology, 14 [11] 1109-1109 (2004).

Pastoreková, S. - Závada, J.
Carbonic anhydrase IX (CA IX) as a potential target for cancer therapy. Rewiev article.
Cancer Therapy, 2, [-] 245-262 (2004).

Šanderová, H. - Hůlková, M. - Maloň, P. - Kepková, M. - Jonák, J.
Thermostability of Multidomain Proteins: Elongation Factors EF-Tu from Escherichia coli and Bacillus stearothermophilus and Their Chimeric Forms.
Protein Science, 13 [1] 89-99 (2004). PubMed

Tolar, P. - Dráberová, L. - Tolarová, H. - Dráber, P.
Positive and negative regulation of Fcepsilon receptor I-mediated signaling events by Lyn kinase C-terminal tyrosine phosphorylation.
European Journal of Immunology, 34 [4] 1136-1145 (2004). PubMed
Tolarová, H. - Dráberová, L. - Heneberg, P. - Dráber, P.
Involvement of filamentous actin in setting the threshold for degranulation in mast cells.
European Journal of Immunology, 34 [6] 1627-1636 (2004). PubMed

Volná, P. - Lebduška, P. - Dráberová, L. - Šímová, Š. - Heneberg, P. - Boubelík, M. - Bugajev, V. - Mallisen, B. - Wilson, B. S. - Hořejší, V. - Mallisen, M. - Dráber, P.
Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.
Journal of Experimental Medicine, 200 [8] 1001-1013 (2004). PubMed

Zavadil, J.* - Čermák, L.* - Soto-Nieves, N. - Bottinger, E. P.
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition.

EMBO Journal, 23, [-] 1155-1165 (2004).  PubMed


  2003

Bartůněk, P. - Králová, J. - Blendiger, G. - Dvořák, M. - Zenke, M.
GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.
Oncogene, 22 [13] 1927-1935 (2003). PubMed

Brdičková, N. - Brdička, T. - Angelisová, P. - Horváth, O. - Špička, J. - Hilgert, I. - Pačes, J. - Simeoni, L. - Kliche, S. - Merten, C. - Schraven, B. - Hořejší, V.
LIME: a new membrane raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling.
Journal of Experimental Medicine, 198 [10] 1453-1462 (2003). PubMed

Bubeník, J. - Mikyšková, R. - Vonka, V. - Mendoza, L. - Šímová, J. - Šmahel, M. - Indrová, M.
Interleukin-2 and dendritic cells as adjuvants for surgical therapy of tumours associated with human papillomavirus type 16.
Vaccine, 21 [9-10] 891-896 (2003). PubMed

Dráberová, L. - Dudková, L. - Boubelík, M. - Tolarová, H. - Šmíd, F. - Dráber, P.
Exogenous administration of gangliosides inhibits FcepsilonRI-mediated mast cell degranulation by decreasing the activity of phospholipase Cgamma.
Journal of Immunology, 171 [7] 3585-3593 (2003). PubMed

Hořejší, V.
The roles of membrane microdomains (rafts) in T cell activation.
Immunological Reviews, 191, [-] 148-164 (2003). PubMed

Králová, J. - Dvořák, M. - Král, V.
Novel cationic transport agents for oligonucleotide delivery into primary leukemic cells.
Journal of Medicinal Chemistry, 46 [11] 2049-2056 (2003). PubMed

Pajer, P. - Pečenka, V. - Karafiát, V. - Králová, J. - Hořejší, Z. - Dvořák, M.
The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma.
Oncogene, 22 [5] 665-673 (2003). PubMed

Vacík, T. - Forejt, J.
Quantification of expression and methylation of the Igf2r imprinted gene in segmental trisomic mouse model.
Genomics, 82, [-] 261-268 (2003). PubMed

Valenta, T. - Lukáš, J. - Kořínek, V.
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells.
Nucleic Acids Research, 31 [9] 2369-2380 (2003). PubMed

Vladimirov, V. - Badalová, J. - Svobodová, M. - Havelková, H. - Hart, A. A. M. - Blažková, H. - Demant, P. - Lipoldová, M.
Different genetic control of cutaneous and visceral disease after Leishmania major infection in mice.
Infection and Immunity, 71 [4] 2041-2046 (2003). PubMed

Vojtěchová, M. - Šloncová, E. - Kučerová, D. - Jiřička, J. - Sovová, V. - Tuháčková, Z.
Initiation factor eIF2B not p70 S6 kinase is involved in the activation of the PI-3K signalling pathway induced by the v-src oncogene.
FEBS Letters, 543, 81-86 (2003). PubMed

Závada, J. - Závadová, Z. - Zaťovičová, M. - Hyršl, L. - Kawaciuk, I.
Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients.
British Journal of Cancer, 89, [-] 1067-1071 (2003). PubMed


 
2002

Bartůněk, P. - Pajer, P. - Karafiát, V. - Blendinger, G. - Dvořák, M. - Zenke, M.
bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.
Oncogene, 21 [3] 400-410 (2002). PubMed

Brdička, T. - Imrich, M. - Angelisová, P. - Brdičková, N. - Horváth, O. - Špička, J. - Hilgert, I. - Lusková, P. - Dráber, P. - Novák, P. - Engels, N. - Wienands, J. - Simeoni, L. - Osterreicher, J. - Aguado, E. - Malissen, M. - Schraven, B. - Hořejší, V.
NTAL (non-T cell activation linker):a transmembrane adaptor protein involved in immunoreceptor signaling.
Journal of Experimental Medicine, 196 [12] 16180-16185 (2002). PubMed

Čermák, L. - Šímová, Š. - Pintzas, A. - Hořejší, V. - Anděra, L.
Apoptosis of TF-1 cells induced by engagement of CD43: roles of transcription, expression of Daxx and adhesion molecules.
Journal of Biological Chemistry, 277 [10] 7955-7961 (2002). PubMed

Dohnálek, J. - Hašek, J. - Dušková, J. - Petroková, H. - Hradilek, M. - Souček, M. - Konvalinka, J. - Brynda, J. - Sedláček, J. - Fábry, M.
Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor.
Journal of Medicinal Chemistry, 45 [7] 1432-1438 (2002). PubMed

Elleder, D. - Pavlíček, A. - Pačes, J. - Hejnar, J.
Preferential integration of human immunodeficiency virus type 1 into genes, cytogenetic R bands and GC-rich DNA regions: insight from the human genome sequence.
FEBS Letters, 517 [1-3] 285-286 (2002). PubMed

Hořejší, V.
Membrane rafts in immunoreceptor signaling: new doubts, new proofs?
Trends in Immunology, 23 [12] 562-564 (2002). PubMed

Králová, J. - Liss, A. S. - Bargmann, W. - Pendleton, C. - Varadarajan, J. - Ulug, E. - Bose, H. R. Jr.
Differential regulation of the inhibitor of the apoptosis ch-IAP1 by v-rel and proto-oncogene c-rel.
Journal of Virology, 76 [23] 11960-11970 (2002).  PubMed

Lácha, J. - Bushell, A. - Smetana, K. - Rossmann, P. - Přibylová, P. - Wood, K. - Malý, P.
Intercellular cell adhesion molecule-1 and selectin ligands in acute cardiac allograft rejection: a study on gene-deficient mouse models.
Journal of Leukocyte Biology, 71, [-] 311-318 (2002). PubMed

Pačes, J. - Pavlíček, A. - Pačes, V.
HERVd: database of human endogenous retroviruses.
Nucleic Acids Research, 30 [1] 205-206 (2002). PubMed

Pavlíček, A. - Clay, O. - Jabbari, K. - Pačes, J. - Bernardi, G.
Isochore conservation between MHC regions on human chromosome 6 and mouse chromosome 7.
FEBS Letters, 511 [1-3] 175-177 (2002). PubMed

Pavlíček, A. - Pačes, J. - Clay, O. - Bernardi, G.
A compact view of isochores in the draft human genome sequence.
FEBS Letters, 511 [1-3] 165-169 (2002).PubMed

Pavlíček, A. - Pačes, J. - Elleder, D. - Hejnar, J.
Processed pseudogenes of human endogenous retroviruses generated by LINEs: their integration, stability, and distribution.
Genome Research, 12 [3] 391-399 (2002). PubMed

Sulimenko, V. - Sulimenko, T. - Poznanovic, S. - Nechiporuk-Zloy, V. - Bohm, K. - Macůrek, L. - Unger, E. - Dráber, P.
Association of brain tubulins with tubulin dimers.
Biochemical Journal, 365 [3] 889-895 (2002). PubMed


  2001

Brdičková, N. - Brdička, T. - Anděra, L. - Špička, J. - Angelisová, P. - Milgram, S. L. - Hořejší, V.
Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton.
FEBS Letters, 507 [2] 133-136 (2001). PubMed

Drbal, K. - Angelisová, P. - Hilgert, I. - Černý, J. - Novák, P. - Hořejší, V.
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
Blood, 98 [5] 1561-1566 (2001). PubMed

Hejnar, J. - Hájková, P. - Plachý, J. - Elleder, D. - Stepanets, V. - Svoboda, J.
CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression.
Proceedings of the National Academy of Sciences, 98 [2] 565-569 (2001). PubMed

Karafiát, V. - Dvořáková, M. - Pajer, P. - Králová, J. - Hořejší, Z. - Čermák, V. - Bartůněk, P. - Zenke, M. - Dvořák, M.
The leucine zipper region of Myb oncoprotein regulates commitment of hematopoietic progenitors.
Blood, 98, 3668-3676 (2001). PubMed

Kovářová, M. - Tolar, P. - Arudchandran, R. - Dráberová, L. - Rivera, J. - Dráber, P.
Structure-function analysis of Lyn kinase association with lipid rafts and intiation of early signaling events after Fc epsilon receptor I aggregation.
Molecular and Cell Biology, 21 [24] 8318-8328 (2001). PubMed

Kozmik, Z. - Machoň, O. - Krešlová, J. - Pačes, J. - Vlček, Č.
Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.
Genomics, 73 [2] 140-148 (2001). PubMed

Kratzerová, L. - Dráberová, E. - Juliano, C. - Viklický, V. - Fiori, P. L. - Cappuccinelli, P. - Dráber, P.
Cell cycle-dependent changes in localization of a 210-kDa microtubule-interacting protein in Leishmania.
Experimental Cell Research, 266 [2] 270-278 (2001). PubMed

Pěknicová, J. - Kubátová, A. - Sulimenko, V. - Dráberová, E. - Viklický, V. - Hozák, P. - Dráber, P.
Differential subcellular distribution of tubulin in boar spermatozoa: Recognition of class III beta-tubulin epitope in sperm tail.
Biology of Reproduction, 65 [3] 672-679 (2001). PubMed

Řezáčová, P. - Lescar, J. - Brynda, J. - Fábry, M. - Hořejší, M. - Sedláček, J. - Bentley, G.
Structural basis of HIV-1 and HIV-2 protease inhibition by a monoclonal antibody.
Structure, 9 [10] 887-895 (2001). PubMed

Říman, J.
A DNA polymerase epsilon inhibitor activates the ribo and deoxyribo modes of primase expression and induces a unique phenomenon of primer accumulation.
FEBS Letters, 505 [1] 141-146 (2001). PubMed

Surviladze, Z. - Dráberová, L. - Kovářová, M. - Boubelík, M. - Dráber, P.
Differential sensitivity to acute cholesterol lowering of activation mediated via the high-affinity IgE receptor and Thy-1 glycoprotein.
European Journal of Immunology, 31 [1] 1-10 (2001). PubMed


 2000

Binarová, P. - Cenklová, V. - Hause, B. - Kubátová, E. - Lysák, M. - Doležel, J. - Bögre, L. - Dráber, P.
Nuclear Gamma-Tubulin during Acentriolar Plant Mitosis.
Plant Cell, 12 [3] 433-442 (2000). PubMed

Brdička, T. - Pavlištová, D. - Leo, A. - Bruyns, E. - Kořínek, V. - Angelisová, P. - Scherer, J. - Shevchenko, A. - Shevchenko, A. Jr. - Hilgert, I. - Černý, J. - Drbal, K. - Kuramitsu, Y. - Kornacker, B. - Hořejší, V. - Schraven, B.
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase Csk and is involved in regulation of T cell activation.
Journal of Experimental Medicine, 191 [9] 1591-1604 (2000). PubMed

Havelková, H. - Badalová, J. - Demant, P. - Lipoldová, M.
A new type of genetic regulation of allogeneic response. A novel locus on mouse chromosome 4, Alan2 controls MLC reactivity to three different alloantigens: C57BL/10, BALB/c and CBA.
Genes and Immunity, 1 [8] 483-487 (2000). PubMed

Kmoch, S. - Brynda, J. - Asfaw, B. - Bezouska, K. - Novak, P. - Rezacova, P. - Ondrova, L. - Filipec, M. - Sedlacek, J. - Elleder, M.
Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography.
Human Molecular Genetics, 9 [12] 1779-1786, 2000. PubMed

Krásný, L. - Vacík, T. - Fučík, V. - Jonák, J.
Cloning and characterization of the str operon and elongation factor Tu expression in Bacillus stearothermophilus.
Journal of Bacteriology, 182 [21] 6114-6122 (2000). PubMed

Lipoldová, M. - Svobodová, M. - Krulová, M. - Havelková, H. - Badalová, J. - Nohýnková, E. - Holáň, V. - Hart, A. - Volf, P. - Demant, P.
Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes.
Genes and Immunity, 1 [3] 200-206 (2000). PubMed

Závada, J. - Závadová, Z. - Pastorek, J. - Biesova, Z. - Ježek, J. - Velek, J.
Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitopes and of the region mediating cell adhesion.
British Journal of Cancer, 82 [11] 1808-1813 (2000). PubMed

Zídek, Z. - Franková, D. - Boubelík, M.
Genetic variation in in-vitro cytokine-induced production of nitric oxide by murine peritoneal macrophages.
Pharmacogenetics, 10 [6] 493-501 (2000). PubMed

Zíková, M. - Sulimenko, V. - Dráber, P. - Dráberová, E.
Accumulation of 210 kDa microtubule-interacting protein in differentiating P19 embryonal carcinoma cells.
FEBS Letters, 473 [1] 19-23 (2000). PubMed


  1999

Angelisová, P. - Drbal, K. - Hořejší, V. - Černý, J.
Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in GPI-anchored proteins and Lyn kinase.
Blood, 93, 1437-1439 (1999). PubMed

Dráberová, L. - Dráberová, E. - Surviladze, Z. - Dráber, P. - Dráber, P.
Protein tyrosine kinase p53/p56lyn forms complexes with
G-tubulin in rat basophilic leukemia cells.
International Immunology, 11 [11] 1829-1839 (1999). PubMed

Drbal, K. - Angelisová, P. - Rasmussen, A. M. - Hilgert, I. - Funderud, S. - Hořejší, V.
The nature of the subset of MHC class II molecules carrying the CDw78 epitopes.
International Immunology, 11 [4] 491-498 (1999). PubMed

Forejt, J. - Saam, J. R. - Gregorová, S. - Tilghman, S. M.
Monoallelic expression of reactivated imprinted genes in embryonal carcinoma cell hybrids.
Experimental Cell Research, 252 [2] 416-422 (1999). PubMed

Havelková, H. - Kosařová, M. - Krulová, M. - Holáň, V. - Demant, P. - Lipoldová, M.
T-cell proliferative response is controlled by locus Tria 3on mouse chromosome 17.
Immunogenetics, 49 [3] 235-237 (1999). PubMed

Hořejší, V. - Drbal, K. - Cebecauer, M. - Černý, J. - Brdička, T. - Angelisová, P. - Stockinger, H.
GPI-microdomains: a role in signalling via immunoreceptors.
Immunology Today, 20 [8] 356-361 (1999). PubMed

Kašpar, P. - Dvořáková, M. - Králová, J. - Pajer, P. - Kozmik, Z. - Dvořák, M.
Myb-interacting Protein, ATBF1, Represses Transcriptional Activity of Myb Oncoprotein.
Journal of Biological Chemistry, 274 [20] 14422-14428 (1999). PubMed

Lescar, J.* - Brynda, J.* - Řezáčová, P. - Štouračová, R. - Riottot, M. M. - Chitarra, V. - Fábry, M. - Hořejší, M. - Sedláček, J. - Bentley, G. A.
Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.
Protein Science, 8 [12] 2686-2696 (1999).  PubMed

Pečenková, T. - Pačes, V.
Molecular Phylogeny of
f29-like Phages and Their Evolutionary Relatedness to Other Protein-Primed Replicating Phages and Other Phages Hosted by Gram-Positive Bacteria.
Journal of Molecular Evolution, 48, 197-208 (1999). PubMed

Plachý, J. - Weining, K. C. - Kremmer, E. - Puehler, F. - Hála, K. - Kaspers, B. - Staeheli, P.
Protective Effects of Type I and Type II Interferons toward Rous Sarcoma Virus-Induced Tumors in Chickens.
Virology, 256, 85-91 (1999). PubMed

Štokrová, J. - Palková, Z. - Fischer, L. - Richterová, Z. - Korb, J. - Griffin, B. E. - Forstová, J.
Interactions of heterologous DNA with polyomavirus major structural protein, VP1.
FEBS Letters, 445 [1] 119-125 (1999). PubMed

Trachtulec, Z. - Forejt, J.
Transcription and RNA processing of mammalian genes in Saccharomyces cerevisiae.
Nucleic Acids Research, 27, 526-531 (1999). PubMed

Tuháčková, Z. - Sovová, V. - Šloncová, E. - Proud, C. G.
Rapamycin-resistant phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in v-src-transformed hamster fibroblasts.
International Journal of Cancer, 81 [6] 963-969 (1999). PubMed


  1998

Binarová, P. - Hause, B. - Doležel, J. - Dráber, P.
Association of G-tubulin with kinetochore/centromeric region of plant chromosomes.
Plant Journal, 14 [6] 751-757 (1998).

Boubelík, M. - Floryk, D. - Bohata, J. - Dráberová, L. - Mačák, J. - Šmíd, F. - Dráber, P.
Lex glycosphingolipids-mediated cell aggregation.
Glycobiology, 8 [2] 139-146 (1998). PubMed

Holáň, V. - Kuffová, L. - Zajícová, A. - Krulová, M. - Filipec, M. - Holler, P. - Jančárek, A.
Urocanic Acid Enhances IL-10 Production in Activated CD4+=T Cells.
Journal of Immunology, 161, 3237-3241 (1998). PubMed

Jonák, J. - Anborgh, P. H. - Parmeggiani, A.
Interaction of EF-Tu with EF-Ts: substitution of His-118 in EF-Tu destabilizes the EF-Tu.EF-Ts complex but does not prevent EF-Ts from stimulating the release of EF-Tu-bound GDP.
FEBS Letters, 422 [2] 189-192 (1998). PubMed

Králová, J. - Liss, A. S. - Bargmann, W. - Bose, H. R.
AP-1 Factors Play an Important Role in Transformation Induced by the v-rel Oncogene.
Molecular and Cellular Biology, 18 [5] 2997-3009 (1998). PubMed

Krásný, L. - Mesters, J. R. - Tieleman, L. N. - Kraal, B. - Fučík, V. - Hilgenfeld, R. - Jonák, J.
Structure and Expression of Elongation Factor Tu from Bacillus stearothermophilus.
Journal of Molecular Biology, 283 [2] 371-381 (1998). PubMed

Surviladze, Z. - Dráberová, L. - Kubínová, L. - Dráber, P.
Functional heterogeneity of Thy-1 membrane microdomains in rat basophilic leukemia cells.
European Journal of Immunology, 28 [6] 1847-1858 (1998). PubMed


  1997

Amoui, M. - Dráberová, L. - Tolar, P. - Dráber, P.
Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fce receptors.
European Journal of Immunology, 27 [2] 321-328 (1997). PubMed

Amoui, M. - Dráber, P. - Dráberová, L.
Src family-selective tyrosine kinase inhibitor, PP1, inhibits both FceRI- and Thy-1-mediated activation of rat basophilic leukemia cells.
European Journal of Immunology, 27, 1881-1886 (1997). PubMed

Bartůněk, P. - Karafiát, V. - Dvořáková, M. - Záhorová, V. - Mandíková, S. - Zenke, M. - Dvořák, M.
The Myb leucine zipper is essential for leukemogenicity of the v-Myb protein.
Oncogene, 15 [24] 2939-2949 (1997). PubMed

Černý, J. - Fišerová, A. - Horváth, O. - Bezouška, K. - Pospíšil, M. - Hořejší, V.
Association of human NK cell surface receptors NKR-P1 and CD94 with Src-family protein kinases.
Immunogenetics, 46 [3] 231-236 (1997). PubMed

Klein, J. - Hořejší, V.
Immunology 2nd edition. Oxford, Blackwell Science 1997. - 722 s. (book)

Krulová, M. - Havelková, H. - Kosařová, M. - Holáň, V. - Hart, A. A. M. - Demant, P. - Lipoldová, M.
IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: A distinct control of the response induced by different IL-2 concentrations.
Genomics, 42 [1] 11-15 (1997). PubMed

Lescar, J. - Štouračová, R. - Riottot, M. M. - Chitarra, V. - Brynda, J. - Fábry, M. - Hořejší, M. - Sedláček, J. - Bentley, G. A.
Three-di
mensional structure of an Fab-peptide complex: structural basis of HIV-1 protease inhibition by a monoclonal antibody.
Journal of Molecular Biology, 267 [5] 1207-1222 (1997). PubMed

Tolar, P. - Dráberová, L. - Dráber, P.
Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells.
European Journal of Immunology, 27, 3389-3397 (1997). PubMed

Trachtulec, Z. - Hamvas, R. M. J. - Forejt, J. - Lehrach, H. R. - Vincek, V. - Klein, J.
Linkage of TATA-Binding Protein and Proteasome Subunit C5 Genes in Mice and Humans Reveals Synteny Conserved between Mammals and Invertebrates.
Genomics, 44, 1-7 (1997). PubMed

Urbánek, P. - Fetka, I. - Meisler, M. H. - Busslinger, M.
Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Proceedings of the National Academy of Sciences of the USA, 94, 5703-5708 (1997). PubMed

Vlček, Č. - Pačes, V. - Maltsev, N. - Pačes, J. - Haselkorn, R. - Fonstein, M.
Sequence of a 189-kb segment of the chromosome of Rhodobacter capsulatus SB 1003.
Proceedings of the National Academy of Sciences of the USA, 94 [ 17] 9384-9388 (1997). PubMed


  1996
Briešťanská, J. - Plachý, J.
Influence of the transduced 3'UTR of the c-src oncogene on tumour growth induced by the v-src gene of avian sarcoma virus PR2257.
Journal of General Virology, 77, 1189-1192 (1996).PubMed

Bubeník, J.
Cytokine gene-modified vaccines in the therapy of cancer.
Pharmacology and Therapeutics, 69 [1] 1-14 (1996).
PubMed

Bubeník, J.
Gene transfer for immunotherapy of cancer.
Gene Therapy, 3 [11] 944-945 (1996).

Černý, J. - Stockinger, H. - Hořejší, V.
Noncovalent association of T lymphocyte surface proteins.
European Journal of Immunology, 26 [10] 2335-2343 (1996). PubMed

Forejt, J.
Hybrid Sterility in the Mouse
Trends in Genetics, 12 [10] 412-417 (1996). PubMed

Havelková, H. - Krulová, M. - Kosařová, M. - Holáň, V. - Hart, A. A. M. - Demant, P. - Lipoldová, M.
Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15.
Immunogenetics, 44 [6] 475-477 (1996).

Holáň, V. - Lipoldová, M. - Demant, P.
Identical genetic control of MLC reactivity to different MHC incompatibilities, independent of production of and response to IL-2.
Immunogenetics, 44 [1] 27-35 (1996). PubMed

Jansa, P. - Forejt, J.
A novel type of retinoic acid response element in the second intron of the mouse H2Kb gene is activated by the RAR/RXR heterodimer.
Nucleic Acids Research, 24, 694-701 (1996).PubMed

   1995

Bohuslav, J. - Hořejší, V. - Hansmann, C. - Stöckl, J. - Weidle, U. - Majdic, O. - Bartke, I. - Knapp, W. - Stockinger, H.
Urokinase plasminogen activator receptor, B2-integrins, and Src-kinases within a single receptor of human monocytes.
Journal of Experimental Medicine, 181, 1381-1390 (1995). PubMed

Brynda, J. - Fábry, M. - Hořejší, M. - Sedláček, J.
The Gag-Pol Encoded Proteinase of an Avian Retrovirus Expressed in Esterichia coli Can Produce a Novel Proteinase (PR+IleGly) That Is Two Amino Acids Larger at Its Carboxy-Terminal Region Than the Major Gag Proteinase (PR).
Virology, 207 [1] 185-190 (1995).PubMed

Cinek, T. - Hilgert, I. - Hořejší, V.
An alternative way of CD4 and CD8 association with protein kinases of the Src family.
Immunogenetics, 41, 110-116 (1995). PubMed

Dráberová, L. - Dráber, P.
Thy-1-mediated activation of rat basophilic leukemia cells does not require co-expression of the high-affinity IgE receptor.
European Journal of Immunology, 25, 2428-2432 (1995). PubMed

Lipoldová, M. - Kosařová, M. - Zajícová, A. - Holáň, V. - Hart, A. A. M. - Krulová, M. - Demant, P.
Separatiom of multiple genes controlling the T cell proliferative response to IL-2 and anti-CD3 using Recombinant Congenic Strains.
Immunogenetics, 41, 301-311 (1995). PubMed

Vlček, Č. - Beneš, V. - Pačes, V. - Lu, Y. - Kutish, G. F. - Rock, D. - Letchworth, G. J. - Schwyzer, M.
Nucleotide sequence analysis of a 30-kb region of the bovine herpesvirus 1 genome which exhibits a colinear gene arrangement with the UL21 to UL4 genes of herpes simplex virus.
Virology, 210, 100-108 (1995). PubMed

Vlček, Č. - Langlois, I. - Styger, D. - Vogt, B. - Simard, C. - Chaligour, A. - Trudel, M. - Schwyzer, M.
Sequence analysis of the UL39, UL38 and UL37 homologues of bovine herpesvirus 1 and expression studies of UL40 and U L39. The subunits of ribonucleotide reductase.
Virology, 212, 734-740 (1995). PubMed



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