Collaboration

Hans-Georg Kräusslich
Department of Virology, University of Heidelberg, Heidelberg, Germany (In vitro analysis of polyprotein processing, culture testing of protease inhibitors)

Alex Wlodawer
National Institutes of Health, Bethesda, USA (Structural biology of HIV PR and its mutants)

Monique Nijhuis
Eijkman-Winklar Centre for Medical Microbiology, Infectious Diseases and Inflamation

Karel Bezouška
Department of Biochemistry, Charles University, Prague (Protein chemistry, analysis of glycosylation of recombinant proteins)

Department of Gene Manipulation, Institute of Molecular Genetics, Academy of Science of the Czech Republic
3-D structure analysis of HIV PR complexes with inhibitors; chymosin and its mutants

AIDS Center, Clinic of Infectious Diseases, Faculty Hospital Bulovka
Long term clinical study on the development of resistance against antiretroviral treatment in HIV positive patients

Vladimír Sklenář
NMR Laboratory, Department of Chemistry, Masaryk University Brno (NMR studies of biomolecules)