2003
Botros S., William S., Hammam O., Zídek Z., Holý A.:
Activity of 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine against Schistosomiasis mansoni in Mice.
Antimicrobial Agents and Chemotherapy 12 (47): 3853-3858, 2003.
Hocková D., Holý A., Masojídková M., Andrei G., Snoeck R., De Clercq E., Balzarini J.:
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines-Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity.
Journal of Medicinal Chemistry 23 (46): 5064-5073, 2003.
Valeriánová M., Otová B., Bila V., Hanzalová J., Votruba I., Holý A., Eckschlager T., Krejèí O., Trka J.:
PMEDAP and its N6-Substituted Derivatives: Genotoxic Effect and Apoptosis in in vitro Conditions.
Anticancer Research 6 C (23): 4933-4939, 2003.
Česnek M., Holý A., Masojídková M.:
New 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl) adenine and their 6-guanidinopurine counterparts as potential effectors of adenosine receptors.
Collection of Czechoslovak Chemical Communications 11 (68): 2201-2218, 2003.
Zídek Z., Potměšil P., Holý A.:
Cytostatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes.
Toxicology and Applied Pharmacology 3 (192): 246-253, 2003.
Gomez-Coca R.B., Holý A., Vilaplana R.A., Gonzalez-Vilchez F., Sigel H.:
Solution structures of binary and ternary metal ion complexes of 9-(5-phosphonopentyl)adenine (3´-deoxa-PEEA). A nucleotide analogue related to the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).
European Journal of Inorganic Chemistry 16 : 2937-2947, 2003.
Zídek Z., Potměšil P., Kmoníčková E., Holý A.:
Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurines.
European Journal of Pharmacology 1-3 (475): 149-159, 2003.
Keith K.A., Hitchcock M.J.M., Lee W.A., Holý A., Kern E.R.:
Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.
Antimicrobial Agents and Chemotherapy 7 (47): 2193-2198, 2003.
Krečmerová M., Buděšínský M., Masojídková M., Holý A.:
Synthesis of optically active N6-alkyl derivatives of (R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds.
Collection of Czechoslovak Chemical Communications 5 (68): 931-950, 2003.
Fernandez-Botello A., Holý A., Moreno V., Sigel H.:
Stability and structure of binary and ternary metal ion complexes in aqueous solution of the quaternary 1-[2-(phosphonomethoxy)ethyl] derivative of 2,4-diaminopyrimidine (PMEDAPy-). Properties of an acyclic nucleotide analogue.
Polyhedron 8 (22): 1067-1076, 2003.
Čapek P., Otmar M., Masojídková M., Votruba I., Holý A.:
A facile synthesis of 9-deaza analogue of olomoucine.
Collection of Czechoslovak Chemical Communications 4 (68): 779-791, 2003.
Doláková P., Masojídková M., Holý A.:
Synthesis of Base Substituted 2-Hydroxy-3-(purin-9-yl)-propanoic Acids and 4-(Purin-9-yl)-3-butenoic Acids.
Nucleosides, Nucleotides and Nucleic Acids 12 (22): 2145-2160, 2003.
Koellner G., Stroh A., Raszewski G., Holý A., Bzowska A.:
Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone.
Nucleosides, Nucleotides and Nucleic Acids 5-8 (22): 1699-1702, 2003.
Wielgus-Kutrowska B., Frank J., Holý A., Koellner G., Bzowska A.:
Interactions of trimeric purine nucleoside phosphorylases with ground state analogues - Calorimetric and fluorimetric studies.
Nucleosides, Nucleotides and Nucleic Acids 5-8 (22): 1695-1698, 2003.
Holý A.:
Phosphonomethoxyalkyl analogs of nucleotides.
Current Pharmaceutical Design 31 (9): 2567-2592, 2003.