2011

Hocek M., Fojta M.:
Nucleobase modification as redox DNA labelling for electrochemical detection
Chem. Soc. Rev. 40: 5802–5814, 2011.

Kielkowski P., Macíčková-Cahová H., Pohl R., Hocek M.:
Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases
Angew. Chem. Int. Ed. 50: 8727–8730, 2011.

Štambaský J., Kapras V., Štefko M., Kysilka O., Hocek M., Malkov A. V., Kočovský P.:
A Modular Approach to Aryl-C-ribonucleosides via the Allylic Substitution and Ring-Closing Metathesis Sequence. A Stereocontrolled Synthesis of All Four α-/β- and D-/L-C-Nucleoside Stereoisomers
J. Org. Chem. 76: 7781–7803, 2011.

Štefko, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.:
General and Modular Synthesis of Isomeric 5-Substituted Pyridin-2-yl and 6-Substituted Pyridin-3-yl C-Ribonucleosides Bearing Diverse Alkyl, Aryl, Hetaryl, Amino, Carbamoyl, and Hydroxy Groups
J. Org. Chem. 76: 6619–6635, 2011.

Standara, S.; Bouzková, K.; Straka, M.; Zacharová, Z.; Hocek, M.; Marek, J.; Marek, R.:
Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines
Phys. Chem. Chem. Phys. 13: 15854–15864, 2011.

Lund T. J.; Cavanaugh N. A.; Joubert N.; Urban M.; Patro J. N.; Hocek, M.; Kuchta, R. D.:
B Family DNA Polymerases Asymmetrically Recognize Pyrimidines and Purines
Biochemistry 50: 7243–7250, 2011.

Nečas D.; Hidasová D.; Hocek M., Kotora M.:
Modular synthesis of 1-α- and 1-β-(indol-2-yl)-2'-deoxyribose C-nucleosides
Org. Biomol. Chem. 9: 5934–5937, 2011.

Fojta M.; Havran L.; Pivoňková H.; Horáková P.; Hocek M.:
Redox Labels and Indicators Based on Transition Metals and Organic Electroactive Moieties for Electrochemical Nucleic Acids Sensing
Curr. Org. Chem. 15: 2936–2949, 2011.

Bourderioux A., Nauš P., Perlíková P., Pohl R., Pichová I., Votruba I., Džubák P., Konečný P., Hajdúch M., Stray K.M., Wang T., Ray A.S., Feng J.Y., Birkus G., Cihlar T., Hocek M.:
Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines
J. Med. Chem. 54: 5498–5507, 2011.

Čerňová M., Čerňa I., Pohl R., Hocek M.:
Regioselective Direct C-H Arylations of Protected Uracils. Synthesis of 5- and 6-Aryluracil Bases
J. Org. Chem. 76: 5309-5319, 2011.

Nauš P., Perlíková P., Pohl R., Hocek M.:
Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2'-C-methylribonucleosides, arabinonucleosides and 2'-deoxy-2'-fluoroarabinonucleosides
Collect. Czech. Chem. Commun. 76: 957-988, 2011.

Stevens K., Claeys D.D., Catak S., Figaroli S., Hocek M., Tromp J.M., Schürch S., Speybroeck V., Madder, A.:
Furan-Oxidation-Triggered Inducible DNA Cross-Linking: Acyclic Versus Cyclic Furan-Containing Building Blocks—On the Benefit of Restoring the Cyclic Sugar Backbone
Chem. Eur. J. 17: 6940-6953, 2011.

Macíčková-Cahová H., Pohl R., Horáková P., Havran L., Špaček J., Fojta M., Hocek M.:
Alkylsulfanylphenyl Derivatives of Cytosine and 7-Deazaadenine Nucleosides, Nucleotides and Nucleoside Triphosphates: Synthesis, Polymerase Incorporation to DNA and Electrochemical Study
Chem. Eur. J. 17: 5833-5841, 2011.

Kielkowski P., Pohl R., Hocek M.:
Synthesis of Acetylene Linked Double-Nucleobase Nucleos(t)ide Building Blocks and Polymerase Construction of DNA Containing Cytosines in the Major Groove
J. Org. Chem. 76: 3457–3462, 2011.

Horáková P., Macíčková-Cahová H., Pivoňková H., Špaček J., Havran L., Hocek M., Fojta M.:
Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl tranferase. Application in electrochemical DNA hybridization and protein-DNA binding assays
Org. Biomol. Chem. 9: 1366 - 1371, 2011.

Macíčková-Cahová H., Pohl R., Hocek M.:
Cleavage of Functionalized DNA Containing 5-Modified Pyrimidines by Type II Restriction Endonucleases
ChemBioChem 12: 431 – 438, 2011.

Perlíková P., Pohl R., Votruba I., Shih R., Birkuš G., Cihlář T., Hocek M.:
Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides
Bioorg. Med. Chem. 19: 229-242, 2011.