Zaměstnanci

Jméno Karel Pomeisl
Pozice Vědecký pracovník
Dr. Karel Pomeisl

Karel Pomeisl, Ph.D.

Scientist


Nucleoside and nucleotide analogues for biomedical applications
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

Phone: (+420) 220 183 475
Fax: (+420) 220 183 560

 
Education
1998-2006 Ph.D. in organic chemistry, under supervision of Prof. O. Paleta at Department of Organic Chemistry, Faculty of Chemical Technology, Institute of Chemical Technology, Prague. Thesis: Study of Syntheses of Some 3-Fluorofuran-2(5H)-ones.
1992-1998 Ing. (equivalent of M.Sc.) in organic chemistry, under supervision of Prof. O. Paleta at Department of Organic Chemistry, Faculty of Chemical Technology, Institute of Chemical Technology, Prague. Diploma thesis: Syntheses of Some 2-Fluoro-2-buten-4-olides from 2-Hydroxyketones.
 
Experience
1998 Short term stay at the Department of Chemistry, Tomás Bata University, Zlín, Czech Republic, in group of Prof. Antonín Klásek (Syntesis of qiuinolin-2,4-dione but-2-enolides).
 
Appointments
since 2010 Scientist, Nucleoside and nucleotide analogues for biomedical applications, Institute of Organic Chemistry and Biochemistry ASCR, v.v.i., Prague.
2003-2010 Member of the Prof. Antonín Holý Research Team, Institute of Organic Chemistry and Biochemistry ASCR, v.v.i., Prague. Research: Syntheses of pyrimidine ANPs as the inhibitors of thymidine phosphorylase and dUTPase.
 
Research interest
Organic, applied bioorganic and medicinal chemistry, good knowledge of fluorine chemistry, syntheses of fluorinated compounds with a potential scale of bioctivities, proposals of the mechanisms and reactivity in fluorine organic reactions, syntheses of pyrimidine acyclic nucleoside phosphonates as potent antitumor components, programs and methodologies in organic, instrumental analytical and bioorganic chemistry.