Publikace za rok 2011

Rejman D, Rabatinová A, Pombinho AR, Kovačková S, Pohl R, Zborniková E, Kolář M, Bogdanová K, Nyč O, Sanderová H, Látal T, Bartůněk P, Krásný L. Lipophosphonoxins: New Modular Molecular Structures with Significant Antibacterial Properties. Journal of Medicinal Chemistry 2011 54(22):7884-7898. 

Jílková A, Rezácová P, Lepsík M, Horn M, Váchová J, Fanfrlík J, Brynda J, McKerrow JH, Caffrey CR, Mares M. Structural basis for inhibition of cathepsin B drug target from the human blood fluke, Schistosoma mansoni. Journal of Biological Chemistry 2011 286(41):35770-81. 

Nejepinska J, Flemr M, Svoboda P. Control of the Interferon Response in RNAi Experiments. Methods in Molecular Biology 2012 820:133-61.

Dong LF, Jameson VJ, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RA, Neuzil J. Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy.  Free Radical Biology and Medicine 2011 50(11):1546-55. 

Hořejší B, Vinopal S, Sládková V, Dráberová E, Sulimenko V, Sulimenko T, Vosecká V, Philimonenko A, Hozák P, Katsetos CD, Dráber P.  Nuclear γ-tubulin associates with nucleoli and interacts with tumor suppressor protein C53. Journal of  Cellular Physiology 2012 227(1):367-82. 

Rohlena J, Dong LF, Kluckova K, Zobalova R, Goodwin J, Tilly D, Stursa J, Pecinova A, Philimonenko A, Hozak P, Banerjee J, Ledvina M, Sen CK, Houstek J, Coster MJ, Neuzil J. Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing. Antioxidant and Redox Signaling 2011 15(12):2923-35.

Makrodouli E, Oikonomou E, Koc M, Andera L, Sasazuki T, Shirasawa S, Pintzas A.  BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study. Molecular Cancer. 2011 10:118.

Hořejší B, Vinopal S, Sládková V, Dráberová E, Sulimenko V, Sulimenko T, Vosecká V, Philimonenko A, Hozák P, Katsetos CD, Dráber P.J. Nuclear γ-tubulin associates with nucleoli and interacts with tumor suppressor protein C53.  Cellular Physiology 2012 227(1):367-82.

Katsetos CD, Dráber P, Kavallaris M.Targeting III-Tubulin in Glioblastoma Multiforme: From Cell Biology And Histopathology To Cancer Therapeutics. Anticancer Agents in Medicinal Chemistry 2011 [Epub ahead of print].

Dráberová E, Vinopal S, Morfini G, Liu PS, Sládková V, Sulimenko T, Burns MR, Solowska J, Kulandaivel K, de Chadarévian JP, Legido A, Mörk SJ, Janáček J, Baas PW, Dráber P, Katsetos CD. Microtubule-severing ATPase spastin in glioblastoma: increased expression in human glioblastoma cell lines and inverse roles in cell motility and proliferation. Journal of Neuropathology and Experimental Neurology 2011 70(9):811-26.

Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T. SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.Molecular and Cellular Biology 2011 31(22):4550-62. 

Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Lama Tamang TD, Khurana MC, Harry EA, Rivera J, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ. A novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (Stat5) tyrosine phosphorylation and the selective influence of Stat5B over mast cell cytokine production. Journal of Biological Chemistry 2011 [Epub ahead of print].

Homolka D, Jansa P, Forejt J. Genetically enhanced asynapsis of autosomal chromatin promotes transcriptional dysregulation and meiotic failure.Chromosoma 2011 [Epub ahead of print].

Boell L, Gregorova S, Forejt J, Tautz D. A comparative assessment of mandible shape in a consomic strain panel of the house mouse (Mus musculus) - implications for epistasis and evolvability of quantitative traits.BMC Evolutionar Biology 2011 11:309.

Svobodova E, Krulova M, Zajicova A, Pokorna K, Prochazkova J, Trosan P, Holan V. The Role of Mouse Mesenchymal Stem Cells in Differentiation of Naive T-Cells into Anti-Inflammatory Regulatory T-Cell or Proinflammatory Helper T-Cell 17 Population. Stem Cells and Development 2011 [Epub ahead of print].

Holan V, Chudickova M, Trosan P, Svobodova E, Krulova M, Kubinova S, Sykova E, Sirc J, Michalek J, Juklickova M, Munzarova M, Zajicova A. Cyclosporine A-loaded and stem cell-seeded electrospun nanofibers for cell-based therapy and local immunosuppression. Journal of Controlled Release 2011 156(3):406-12. 

Prochazkova J, Pokorna K, Holan V. IL-12 inhibits the TGF-β-dependent T cell developmental programs and skews the TGF-β-induced differentiation into a Th1-like direction. Immunobiology 2012 217(1):74-82. 

Reiss K, Meyer-Hoffert U, Fischer J, Sperrhacke M, Wu Z, Dimitrieva O, Krenek P, Suchanova S, Buryova H, Brauer R, Sedlacek R. Expression and regulation of murine SPINK12, a potential orthologue of human LEKTI2. Experimental Dermatology 2011 20(11):905-10. 

Kasparek P, Krenek P, Buryova H, Suchanova S, Beck IM, Sedlacek R. Transgenic mouse model expressing tdTomato under involucrin promoter as a tool for analysis of epidermal differentiation and wound healing. Transgenic Research 2011 [Epub ahead of print].

Hnilicová J, Staněk D. Where splicing joins chromatin. Nucleus 2011 2(3):182-8. 

Grekov I, Svobodová M, Nohýnková E, Lipoldová M. Preparation of highly infective Leishmania promastigotes by cultivation on SNB-9 biphasic medium. Journal of Microbiological Methods 2011 87(3):273-7. 

Stechova K, Kolar M, Blatny R, Halbhuber Z, Vcelakova J, Hubackova M, Petruzelkova L, Sumnik Z, Obermannova B, Pithova P, Stavikova V, Krivjanska M, Neuwirth A, Kolouskova S, Filipp D.Healthy first degree relatives of patients with type 1 diabetes exhibit significant differences in basal gene expression pattern of immunocompetent cells compared to controls: expression pattern as predeterminant of autoimmune diabetes. Scandinavian Journal of Immunology 2011 [Epub ahead of print].

Uhlik O, Strejcek M, Junkova P, Sanda M, Hroudova M, Vlcek C, Mackova M, Macek T. Matrix-Assisted Laser Desorption Ionization (MALDI)-Time of Flight Mass Spectrometry- and MALDI Biotyper-Based Identification of Cultured Biphenyl-Metabolizing Bacteria from Contaminated Horseradish Rhizosphere Soil. Applied and Environmental Microbiology 2011 77(19):6858-66. 
DOI: 10.1128/AEM.05465-11

Hovorakova M, Prochazka J, Lesot H, Smrckova L, Churava S, Boran T, Kozmik Z, Klein O, Peterkova R, Peterka M. Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor. Journal of Experimental Zoology part B- Molecular and Developmental  Evolution 2011 316(5):347-58. 
DOI: 10.1002/jez.b.21408

Stachura DL, Svoboda O, Lau RP, Balla KM, Zon LI, Bartunek P, Traver D. Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood  2011 118(5):1274-82. 
DOI:10.1182/blood-2011-01-331199

Bartkova J, Moudry P, Hodny Z, Lukas J, Rajpert-De Meyts E, Bartek J. Heterochromatin marks HP1γ, HP1α and H3K9me3, and DNA damage response activation in human testis development and germ cell tumours. International  Journal of Andrology 2011 34 (4):e103-13.
DOI:10.1111/j.1365-2605.2010.01096.x

Benes J, Kazdova L, Drahota Z, Houstek J, Medrikova D, Kopecky J, Kovarova N, Vrbacky M, Sedmera D, Strnad H, Kolar M, Petrak J, Benada O, Skaroupkova P, Cervenka L, Melenovsky V. Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats. Clinical Science (Lond) 2011 Jul 121(1):29-41.

Melenovsky V, Benes J, Skaroupkova P, Sedmera D, Strnad H, Kolar M, Vlcek C, Petrak J, Benes J Jr, Papousek F, Oliyarnyk O, Kazdova L, Cervenka L. Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats. Molelular and Cellular Biochemistry 2011 Aug 354(1-2):83-96.
DOI:10.1007/s11010-011-0808-3

Oikonomou E, Koc M, Sourkova V, Andera L, Pintzas A. Selective BRAFV600E Inhibitor PLX4720, Requires TRAIL Assistance to Overcome Oncogenic PIK3CA Resistance. PLoS One 2011 6(6): e21632.
DOI: 10.1371/journal.pone.0021632 

Potůčková L, Franko F, Bambousková M, Dráber P. Rapid and sensitive detection of cytokines using functionalized gold nanoparticle-based immuno-PCR, comparison with immuno-PCR and ELISA. Journal of Immunological Methods 2011 Aug 371(1-2):3 8-47.
DOI:10.1016/j.jim.2011.06.012 

Podolska K, Svoboda P. Targeting genes in living mammals by RNA interference. Briefings in functional genomics  July 2011 10(4): 238-247.

Klíma M, Broučková A, Koc M, Anděra L. T-cell activation triggers death receptor-6 expression in a NF-κB and NF-AT dependent manner. Molecular  Immunology 2011 Jul 48(12-13): 1439-47. 
DOI:10.1016/j.molimm.2011.03.021 

Brauer R, Beck IM, Roderfeld M, Roeb E, Sedlacek R. Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogen. BMC Biochemistry 2011 Jul 12(1): 38. 
DOI:10.1186/1471-2091-12-38

Ormsby T, Schlecker E, Ferdin J, Tessarz AS, Angelisová P, Köprülü AD, Borte M, Warnatz K, Schulze I, Ellmeier W, Horejsí V, Cerwenka A. Btk is a positive regulator in the TREM-1/DAP12 signaling pathway. Blood 2011 Jul  118(4):936-45.
DOI:10.1182/blood-2010-11-317016

Stepanek O, Kalina T, Draber P, Skopcova T, Svojgr K, Angelisova P, Horejsi V, Weiss A, Brdicka T. Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148. Journal of Biological  Chemistry 2011 Jun  286(25): 22101-12.
DOI:10.1074/jbc.M110.196733  

Dong LF, Jameson VJ, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RA, Neuzil J.Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy. Free Radical Biology and Medicine June 2011 50(11): 1546-1555. 

Síma M, Havelková H, Quan L, Svobodová M, Jarošíková T, Vojtíšková J, Stassen AP, Demant P, Lipoldová M. Genetic control of resistance to Trypanosoma brucei brucei infection in mice. PLoS Neglected Tropical Diseases 2011 Jun 5(6): e1173.
DOI:10.1371/journal.pntd.0001173   

Szabó P, Kolář M, Dvořánková B, Lacina L, Štork J, Vlček Č, Strnad H, Tvrdek M, Smetana K Jr. Mouse 3T3 fibroblasts under the influence of fibroblasts isolated from stroma of human basal cell carcinoma acquire properties of multipotent stem cells. Biology of the Cell 2011 May 103(5):233-48.
DOI:10.1042/BC20100113:

Bubeník J. Interleukin 12 in cancer treatment. Folia Biologica  2011 57(1):  1-2.
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Cai B, Katafiasz D, Hořejší V,  Naslavsky N. Pre-sorting endosomal transport of the GPI-anchored protein, CD59, is regulated by EHD1. Traffic 2011 12(1): 102-120. 
DOI: 10.1111/j.1600-0854.2010.01135.x

Doubravska L, Krausova M, Gradl D, Vojtechova M, Tumova L, Lukas J, Valenta T, Pospichalova V, Fafilek B, Plachy J, Sebesta O, Korinek V. Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling. Cellular Signalling 2011 23(5): 837-48.
DOI: 10.1016/j.cellsig.2011.01.007

Flemr M,  Svoboda P. Ribonucleoprotein localization in mouse oocytes. Methods 2011 53(2): 136-141.
 DOI: 10.1016/j.ymeth.2010.08.005

Hájková Z,  Bugajev V, Dráberová E, Vinopal S, Dráberová L, Janáček J, Dráber P, Dráber P. STIM1-Directed Reorganization of Microtubules in Activated Mast Cells. 
Journal of Immunology 2011 186(2): 913-923.
PubMed

Hnilicová J, Hozeifi S, Dušková E, Icha J, Tománková T, Staněk D. Histone deacetylase activity modulates alternative splicing. PLoS One 2011 6(2): e16727. 
DOI: 10.1371/journal.pone.0016727

Homolka D, Ivánek R, Forejt J, Jansa P. Differential expression of non-coding RNAs and continuous evolution of the X chromosome in testicular transcriptome of two mouse species.
PLoS ONE 2011 6(6): e17198-e17198.
PubMed

Horakova H, Polakovicova I, Shaik GM, Eitler J, Bugajev V, Draberova L, Draber P. 1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer. BMC Biotechnology 2011 11(1): 41.
DOI: 10.1186/1472-6750-11-41 

Hrdinka M, Dráber P, Stepánek O, Ormsby T, Otáhal P, Angelisová P, Brdicka T, Paces J, Horejsí V, Drbal K. PRR7 Is a Transmembrane Adaptor Protein Expressed in Activated T Cells Involved in Regulation of T Cell Receptor Signaling and Apoptosis. Journal of  Biological  Chemistry 2011 286(22): 19617-29. 
DOI:10.1074/jbc.M110.175117 

Indrová M, Šímová J, Bieblová J, Bubeník J, Reiniš M. NK1.1+ cells are important for the development of protective immunity against MHC I-deficient, HPV16-associated tumours.
Oncology Reports 2011 25(1): 281-288.
DOI: 10.3892/or_00001072

Košař M, Bartkova J, Hubáčková S, Hodný Z, Lukas J, Bartek J. Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner, and follow expression of p16 (ink4a). Cell Cycle 2011 10(3): 457-468.
DOI: 10.4161/cc.10.3.14707

Kozmiková I, Smolíková J, Vlček Č, Kozmik Z. Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning. PLoS ONE 2011 6(2): e 14650.
DOI: 10.1371/journal.pone.0014650

Krejčiříková V, Pachl P, Fábry M, Malý P, Řezáčová P, Brynda J. Structure of the mouse galectin-4 N-terminal carbohydrate-recognition domain reveals the mechanism of oligosaccharide recognition. Acta Crystallographica Section D-Biological Crystallography 2011 67(Pt3): 204-211.
DOI: 10.1107/S0907444911004082

Lenčová A, Pokorná K, Zajícová A, Krulová M, Filipec M, Holáň V. Graft survival and cytokine production profile after limbal transplantation in the experimental mouse model. Transplant Immunology 2011 24(3): 189-94. 
DOI: 10.1016/j.trim.2010.11.005 WOS

 Mader P, Brynda J, Gitto R, Agnello S, Pachl P, Supuran CT, Chimirri A, Řezáčová P. Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides. Journal of Medicinal Chemistry 2011 54(7): 2522-6 .DOI: 10.1021/jm2000213

 Maňásková-Postlerová P, Davidová N, Sulc M, Philimonenko A, Hozák P, Jonáková V. Reproductive tissue expression and sperm localization of porcine beta-microseminoprotein. Cell and Tissue Research 2011 344(2): 341-53. 
DOI: 10.1007/s00441-011-1149-y 

Merjava S, Neuwirth A, Tanzerova M, Jirsová K. The spectrum of cytokeratins expressed in the adult human cornea, limbus and perilimbal conjunctiva. Histology and Histopathology  2011 26(3): 323-331.
PubMed

Mikyšková R, Indrová M, Šímová J, Bieblová J, Bubeník J, Reiniš M. Genetically modified tumour vaccines producing IL-12 augment chemotherapy of HPV16-associated tumours with gemcitabine. Oncology  Reports 2011 25(6): 1683-9. 
DOI:10.3892/or.2011.1221

Novotný I, Blažíková M, Staněk D, Heřman P, Malínský J. In vivo kinetics of U4/U6.U5 tri-snRNP formation in Cajal bodies. Molecular Biology of the Cell  2011 22(4): 513-523. DOI: DOI:10.1091/mbc.E10-07-0560

Otáhal P, Pata S, Angelisová P, Hořejší V, Brdička T. The effects of membrane compartmentalization of csk on TCR signaling. Biochimica and  Biophysica Acta. 2011 1813(2): 367-76. 
DOI: 10.1016/j.bbamcr.2010.12.003 

Philimonenko A, Janáček J, Snyers L, Almeder M, Berger W, Schmidt W, Schofer C, Hozák P. Chromosomal dynamics of cell cycle regulator gene p21 during transcriptional activation. Journal of Stuctural Biology 2011 173(2): 382-390.
DOI: 10.1016/j.jsb.2010.10.010

Pospichalova V, Tureckova J, Fafilek B, Vojtechova M, Krausova M, Lukas J, Sloncova E, Takacova S, Divoky V, Leprince D, Plachy J, Korinek V. Generation of two modified mouse alleles of the Hic1 tumor suppressor gene. Genesis 2011 49(3): 142-51. 
DOI: 10.1002/dvg.20719

Rohoušová I, Hostomská J, Vlková M, Kobets T, Lipoldová M, Volf P. The protective effect against Leishmania infection conferred by sand fly bites is limited to short-term exposure. International Journal of Parasitology 2011 41(5): 481-5.
DOI: 10.1016/j.ijpara.2011.01.003 WOS

Sedlák D, Paguio A, Bartůněk P. Two panels of steroid receptor luciferase reporter cell lines for compound profiling. Combinatorial  Chemistry and  High Throughput Screening 2011 14(4): 248-66.
 
Sobol M, Nebesářová J, Hozák P. A method for preserving ultrastructural properties of mitotic cells for subsequent immunogold labeling using low-temperature embedding in LR White resin. Histochemistry and Cell Biology 2011 135(1): 103-110.
DOI: 10.1007/s00418-010-0771-1

Strnad H, Rídl J, Pačes J, Kolář M, Vlček Č, Pačes V. Complete genome sequence of the haloaromatic acid-degrading bacterium Achromobacter xylosoxidans A8. Journal of Bacteriology 2011 193(3): 791-792.
DOI: 10.1128/JB.01299-10

Šlouf M, Pavlova E, Bhardwaj M, Pleštil J, Onderková H, Philimonenko A, Hozák P. Preparation of stable Pd nanoparticles with tunable size for multiple immunolabeling in biomedicine. Materials Letters 2011 65(8): 1197-1200.
 DOI: 10.1016/j.matlet.2011.01.046

Štěpánek O, Brdička T, Angelisová P, Horváth O, Špička J, Stockbauer P, Man P, Hořejší V. Interaction of late apoptotic and necrotic cells with vitronectin. PLoS One 2011 6(5): e19243. 
DOI: 10.1371/journal.pone.0019243 

Teixeira AR, Gomes C, Nitz N, Sousa AO, Alves RM, Guimaro MC, Cordeiro C, Bernal FM, Rosa AC, Hejnar J, Leonardecz E, Hecht MM. Trypanosoma cruzi in the chicken model: Chagas-like heart disease in the absence of parasitism. PLoS Neglected Tropical Diseases  2011 5(3): e1000.
DOI:10.1371/journal.pntd.0001000 

Vlček Č, Marande W, Teijeiro S, Lukeš J, Burger G. Systematically fragmented genes in a multipartite mitochondrial genome. Nucleic Acids Research 2011 39(3): 979-988.
DOI: 10.1093/nar/gkq88

Vondálová Blanářová O, Jelínková I, Szoor A, Skender B, Souček K, Horváth V, Vaculová A, Anděra L, Sova P, Szollosi J, Hofmanová J, Vereb G, Kozubík A. Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway. Carcinogenesis 2011 32(1): 42-51.
DOI: 10.1093/carcin/bgq220