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Grant projects implemented at IMG in 2005

2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012


Grant Agency Grant No. CPR Duration Grant Investigator Group
GSF
 301/04/0492
 GA301/04/0492
 2004-2006
 M. Reiniš
 11
Grant Name
Immunotherapy of MHC class I- Tumours: Modulation of the MHC Class I Expression by Demethylation, Selection of Proper Adjuvants.

Grant Agency Grant No. CPR Duration Grant Investigator Group
GSF
 310/05/H533
 ---
 2005-2008
 M. Reiniš 11
Grant Name
Study of infectious diseases and their aetiologic agents.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 IGA MH CR NR8004   NR8004
2004-2006   M. Indrová
(co-investigator)
 11
Grant Name
Combined immunotherapy of human papillomavirus-induced tumours.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 IGA MH CR NR7807  NR7807  2004-2006 M. Reiniš   11
Grant Name
Tumours of human papillomavirus origin with different expression of MHC class I molecules: theoretical principles of immunotherapy.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 523/04/0489   GA523/04/0489
 2004-2006 J. Geryk
 12
Grant Name
Pathogenic Effects of Avian Leukosis Virus (ALV) Infection: Molecular and Genetic Aspects.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/05/0939  GA204/05/0939 2005-2007  J. Hejnar  12 
Grant Name
CpG methylation of human endogenous retroviruses and LINEs.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 523/04/0569   GA523/04/0569  2004 - 2006  J. Hejnar  12
Grant Name
RNA interference: applications in chickens.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR
 NR8323  --- 2005-2007  E. Matoušková
(co-investigator) 		 14 
Grant Name
Prognostic and predictive factors of breast carcinoma.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR IBS5052312   IBS5052312
2003-2005
 E. Matoušková 14 
Grant Name
Optimization of application of artificial recombined skin for preventing conversion of deep dermal to full thickness burns.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF 524/04/0102   GA524/04/0102
  2004-2006  E. Pokorná
(co-investigator)
14 
Grant Name
Study of the immunologic response after devitalization of tumours in various animal models.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 IGA MH CR NR8145   NR8145
 2004-2006  E. Matoušková  14
Grant Name
Biology of the interaction of chemosensors with cells of ovarian and breast tumours tested for chemoresistance in vitro and consequences for therapeutic indication.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR  NR8345  NR8345  2005-2008 E. Matoušková
(co-investigator)
14 
Grant Name
Experimentally modified expression of sequence variants of  BRCA1 and BRCA2 genes in primary mammary cells in vitro: effect on the genesis of breast carcinoma and its influencing with various antitumour treatment modalities in bearers of hereditary mutations.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NR8323   NR8323
 2005-2007  P.Veselý (co-investigator)
 14
Grant Name
Prognostic and predictive factors of breast carcinoma.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
HHMI
55000323   --- 2001-2005   M. Lipoldová
  15
Grant Name
Genetic analysis of the immune response.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF  310/03/1381  GA310/03/1381  2003-2005 M. Lipoldová   15
Grant Name
Genetic analysis of immune response.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF  310/03/H147 GD310/03/H147 2003-2007  M. Lipoldová (co-investigator)
15 
Grant Name
Immune regulation mechanisms and their utilization for new preventive and therapeutic protocols.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF 301/02/D159   GP301/02/D159  2002-2005 J. Turečková  16 
Grant Name
Regulation of PKC beta 2 in malignant and differentiating colorectal adenocarcinoma cells.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 301/04/0550   GA301/04/0550
2004-2006  Z. Tuháčková   16
Grant Name
Alternations in translational control through signal transduction pathways in v-Src-transformed cells as a model target for cancer therapy.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
FP6   018094 (MACROCEPT)  --- 2005-2007  V. Holáň (co-investigator)
19 
Grant Name
Tergeted Therapies For Inflammatory Bowel Disease.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF  310/02/D162
 ---  2002-2005 M. Krulová  19
Grant Name
Molecular mechanisms of the effector phase of transplantation reaction after mucosal immunisation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 IGA MH CR NR8340
  NR8340  2005-2007 V. Holáň (co-investigator)
 19
Grant Name
Characteriation and modulation of the risk factors of human corneal transplants leading to immunologic rejection.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR  NI7531  NI7531  2003-2005 V. Holáň (co-investigator)
 19
Grant Name
Role of non-specific immunity in the rejection process, tolerance of failure of the corneal transplant.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NR7816   NR7816
 2004-2006  V. Holáň 19 
Grant Name
Cellular and molecular mechanisms of xenotransplantation reaction. Experimental model of corneal transplantation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR IAA5052406   IAA5052406
2004-2008  Z. Trachtulec  21 
Grant Name
Analysis of haplotypes in wild and wild-derived mice on chromosome 17.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 301/05/0738   GA301/05/0738
2005-2007  Z. Trachtulec 21 
Grant Name
Identification and analysis of groups of conserved syntenic genes by methods of bioinformatics and molecular genetics.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 HHMI  55000306  --- 2001-2005  J. Forejt   21
Grant Name
New tools for genome scanning and positional cloning of mouse complex traits loci.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 NIH  1R01  --- 2004-2007  J. Forejt  21 
Grant Name
Consomic strains between C57/BL/6 and PWD.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GA AS CR IAA5052310   IAA5052310
 2003-2006  Pe. Dráber
 22 
Grant Name
Regulatory roles of Lyn kinase in mast cell activation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 301/03/0596  GA301/03/0596 2003-2005
L. Dráberová  22 
Grant Name
Functional and structural heterogeneity of membrane microdomains in mast cells activated via dimerized IgE receptor.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/03/0594   GA204/03/0594  2003-2005 Pe. Dráber   22
Grant Name
Nonreceptor tyrosine phosphatases in antigen activated mast cells.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 HHMI-INTNL
 55000304   --- 2001-2005  Pe. Dráber  22 
Grant Name
Regulatory role of membrane microdomains in mast cell signaling.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NR8079 NR8079
2004-2006  Pe. Dráber (co-investigator) 22 
Grant Name
Role of glycosfingolipids, immune mechanisms and inflammation in the pathogenesis of experimental and clinical cholestasis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
AS CR
 S5052201   IBS5052201
2002-2005  M. Boubelík  22 
Grant Name
Optimization of DNA segments amplification by polymerase chain reaction.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 AS CR
 1QS500520551  ---  2005-2009  M. Boubelík  22 
Grant Name
New generation of products for amplification of DNA fragments using polymerase chain reaction.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR   
 KJB5052407   KJB5052407
 2004-2005   L. Čermák 23 
Grant Name
The role of adhesion molecules in the regulation of TRAIL-induce apoptosis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GA AS CR IAA5052304   IAA5052304
2003-2006  L. Anděra
23 
Grant Name
Characterization of a role of the adapter protein Daxx in the initiation and regulation of apoptosis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF 204/04/0532   GA204/04/0532
 2004-2006 V. Kořínek 23 
Grant Name
Novel components of the Wnt signaling pathway.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR 
NR8317  NR8317
  2005-2008 L. Anděra (co-investigator)
 23
Grant Name
Study of human leukemic stem cells and progenitors.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
MPO  FT-TA2/015
 FT-TA2/015  2005-2007  L. Anděra (co-investigator)
23 
Grant Name
Development and preparation of recombinant proteins derived from the antigenic structure of Epstein-Barr virus EBNA1 protein and their utilization for diagnostics of infectious diseases.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
ME CR   EUREKA – OE138 OE138  2004-2006  L. Anděra 23 
Grant Name
Preparation of monoclonal antibodies against TRAIL receptors DR4 and DR5 and their prospective utilization for tumour therapy.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
FP6 
12919 (HYBLIB) NEST
  ---  2005-2008 V. Hořejší  24 
Grant Name
Human monoclonal antibodies from a library of hybridomas.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 ME CR EUREKA- 1P04OE190   1P04OE190  2005-2007 P. Angelisová   24
Grant Name
RECAN Recombinant signalling proteins for preparation of comercially relevant polyclonal and monoclonal antibodies. 

Grant Agency Grant No. CPR Duration Grant Investigator Group  
ME CR  1M68378050001   1M0506 2005-2009  V. Hořejší   24
Grant Name
Center of Molecular and Cellular Immunology.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF 304/03/0090   GA304/03/0090
 2003-2005  P. Malý  25 
Grant Name
Studies of the mouse galectin-4 and its recombinant CRD domains in relation to the binding of saccharides and recognition of cell ligands.

nt Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/05/H023   --- 2005-2008   Pa. Dráber 26 
Grant Name
Molecular biology of differentiating cell.

rant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/05/2375   GA204/05/2375
  2005-2007 Pa. Dráber  26 
Grant Name
Analysis and regulation of gamma-tubulin forms associated with membrane microdomains.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF  304/04/1273  GA304/04/1273 2004-2006  E. Dráberová   26
Grant Name
Analysis of gamma-tubulin forms and other spindle pole components.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 FP6 INTAS 03-51-6459   --- 2004-2007  Pa. Dráber  26 
Grant Name
The functional role of microtubule phosphorylation in plant development and environmental stimuli response.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 ME CR  NEURO-1PO4OE158  1PO4OE158  2004-2006 Pa. Dráber  26 
Grant Name
Preparation of  monoclonal antibodies against cytoskeletal and signalling molecules for monitoring neurodegenerative processes.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 ME CR LC545   LC545 2005-2009   Pa. Dráber 26 
Grant Name
Center of Cell Functional Organization.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 ME CR 1P05ME776   1P05ME776 2005 - 2008  V. Viklický  26 
Grant Name
Participation in the proceedings of bioethics committees .

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 AS  CR
 IBS5052301  IBS5052301
2003-2005   V. Viklický  26
Grant Name
Monoclonal antibodies for diagnosis of neuronal tumours and monitoring of neurodegenerative processes.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR A5052402
 IAA5052402  2004-2006 J. Kovář
 27
Grant Name
Transport of low-molecular-mass iron into human cells: identification of transport molecules.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR B5052401   KJB5052401
 2004-2005  Z. Naďová   27
Grant Name
Mechanisms of programmed cell death completion in human tumor cells: induction by iron deprivation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 305/03/0287   GA305/03/0287 2003-2005   J. Čapková (co-investigator)
27 
Grant Name
Etiology of ANKENT - experimental model for human ankylosing spondylitis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF
 524/03/0178  GA524/03/0178
 2003-2005  J. Pěknicová (co-investigator)
 27
Grant Name
Detailed study of spermatozoa in model species of chondrostean (Chondrostei) and teleostean (Telostei) fish.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NL7567 NL7567  2003-2005 J. Kovář (co-investigator)
27 
Grant Name
Influence of polyphenols and chelates on the toxicity and effect of anthracyclins and taxanes.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NL7567 NL7567  2003-2005 J. Kovář (co-investigator)
27 
Grant Name
Influence of polyphenols and chelates on the toxicity and effect of anthracyclins and taxanes.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NJ7463 NJ7463  2003-2005 J. Pěknicová   27 
Grant Name
Male infertility, sperm and seminal plasma state, damage biomarkers.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
IGA MH CR NR7838
 NR7838
2004-2006   J. Pěknicová (co-investigator)
 27
Grant Name
Participation of immunopathological mechanisms in repeated failure of embryo nidation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/04/1358   GA204/04/1358
  2004-2006 Z. Kozmik  29 
Grant Name
  The role of wnt signalling in eye development and lens cell differentiation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 FP5  V.RP – QLK2  ---  2003-2005 J. Sedláček  31 
Grant Name
Rational approaches towards understanding and overcoming HIV protease inhibitor resistance.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 203/05/2141   GA203/05/2141 2005-2007  Ondráček (co-investigator)
31 
Grant Name
Organic Synthesis in Protein Crystals.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 MIT FD-K3/001  FD-K3/001
 2003-2005  J. Sedláček  31 
Grant Name
Development of new radiopharmaceuticals based on monoclonal and recombinant antibodies .

Grant Agency Grant No. CPR Duration Grant Investigator Group  
ME CR  IM4635608802   1M0505 2005-5009  M. Fábry 31 
Grant Name
Center for Targeted Therapeutics.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF  204/03/H066  GD204/03/H066 2003-2007   V. Pačes 33 
Grant Name
Molecular mechanisms of cellular interactions.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 ME CR 1M68378050   1M0520 2005-2009  V. Pačes  33 
Grant Name
Center for Applied Genomics.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF 303/04/P070   303/04/P070 2004-2006  P. Maňásková 35 
Grant Name
The role of proteins of the male reproductive tract in some phases of reproduction.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GSF  303/05/0614  GA303/05/0614 2005-2007  B. Železná (co-investigator)
35 
Grant Name
Central and peripheral pathways underlying feefing-related effects of cocaine and amphetamine regulated transcript (CART) peptides.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GA AS CR IAA5052309   IAA5052309 2003-2005  M. Dvořák 36 
Grant Name
Molecular mechanism of proliferation of leukemie monoblasts activated by v-Myb oncoprotein.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
 GA AS CR AV0Z5052915-IO44   --- 1.9.2004-31.8.2005  Z. Hořejší  36 
Grant Name
Asymmetric division of stem cells in the early vertebrate embryo.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR AV0Z5052915-I045   --- 1.9.2004-31.8.2005  P. Pajer  36 
Grant Name
Identification and characterization of novel oncogenes using retrovirus-induced chicken nephroblastomas.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 301/04/1315   301/04/1315 2004-2006   J. Králová
  36
Grant Name
Induction of apoptosis by macrocyclic compounds in cancer cells.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 304/03/0463   GA304/03/0463 2003-2005  M. Dvořák  36 
Grant Name
The role of c-myb gene in the early vertebrate embryogenesis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/03/0593   GA204/03/0593 2003-2005  J. Korb  37 
Grant Name
Studies of molecular mechanism of polyomavirus infection aimed to the development of capsid-like particles for the gene delivery system.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
EMBO/HHMI Scientist Award 
   --- 2004-2006  P. Bartůněk  38 
Grant Name
Hematopoietic Cell Differentiation.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
Volkswagen Stiffung  I/77 849   --- 2002-2005  P. Bartůněk (co-investigator)
38 
Grant Name
Nuclear Hormone Receptors in normal and malignant hematopoiesis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR A5052206   IAA5052206
  2002-2005 J. Jonák  39 
Grant Name
Gene ybxF, a newly identified member of the streptomycin operon of Bacillus subtilis.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GA AS CR KJB500520503   KJB500520503  2005-2006  H. Šanderová  39
Grant Name
Elongation factor Tu G-domains: proteins for the study of structural elements of thermostability.

Grant Agency Grant No. CPR Duration Grant Investigator Group  
GSF 204/05/P510   GP204/05/P510  2005-2007 L. Krásný   39
Grant Name
Interaction of Bacillus subtilis rRNA Promoters with RNA polymerase: Defining Elements Required for Regulation of Transcription Initiation.


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