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Grant projects implemented at IMG in 2007

    2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012

Grant Agency:   GSF                   
Grant No: 310/05/H533
Grant Name: Study of infectious diseases and their causative agents
Duration: 2005-2008
Project Investigator: M. Reiniš
Group: 11
Project Agency:   FP6 EU
Project No.: Network of Excellence    018933    Clinigene
Project Name: European Clinical Gene Transfer Advisory Network
Duration: 2005-2009
Project Investigator: J. Bubeník
Group: 11
Project Agency:   GSF      
Project No.: 301/06/0774
Project Name: Role of NK, Th and tumour-infiltrating cells in chemotherapy and gene therapy of MHC I-defficient HPV 16-associated tumours       
Duration: 2006-2008
Project Investigator: M. Indrová
Group: 11
Project Agency:   GA AS CR             
Project No.: A500520605 
Project Name: Induction of immunity against HPV16 E6/E7 oncogenes-induced tumours with peptide- and dendritic cell-based vaccines; immunotherapy of minimal residual tumour disease
Duration: 2006-2009
Project Investigator: M. Reiniš
Group: 11
Project Agency:   GSF          
Project No.: 204/05/0939  
Project Name: CpG methylation of human endogenous retroviruses and LINEs
Duration: 2005-2007  
Project Investigator: J. Hejnar
Group: 12
Project Agency:   GSF     
Project No.: 523/07/1282
Project Name: Characterization of the cellular receptor Tvc and its role in the pathogenesis of avian leukosis viruses subgroup C-induced diseases
Duration: 2007-2009
Project Investigator: J. Geryk
Group: 12
Project Agency:   GSF               
Project No.: 523/07/1171
Project Name: L1 retrotransposon-based transgenic chicken models
Duration: 2007-2009
Project Investigator: J. Hejnar
Group: 12
Project Agency:   EU              
Project No.: 037377 
Project Name: Engineering of the porcine genome for xenotransplantation studies in primates: a step towards clinical application
Duration:
Project Investigator: J. Hejnar
Group: 12
Project Agency:   GA AS CR          
Project No.: IAA500520709
Project Name: Mechanisms of syncytin-mediated cell-to-cell fusion in placenta 
Duration: 2007-2009  
Project Investigator: J. Hejnar
Group: 12
Project Agency:   GSF               
Project No.: 204/07/1030
Project Name: Integration preference of retroviruses
Duration: 2007-2009
Project Investigator: J. Plachý
Group: 12
Project Agency:   GA AS CR              
Project No.: IAA500520707
Project Name: The role of innate immune molecules in embryonic homeostasis and sterile inflammation
Duration: 2007-2011 
Project Investigator: D. Filipp
Group: 13
Project Agency:   GSF         
Project No.: 204/05/0920
Project Name: Functional consequences of GABAb receptor and the deubiquitinating enzyme USP14 association 
Duration: 2005-2007 
Project Investigator: J. Blahoš
Group: 14
Project Agency:   GA AS CR            
Project No.: IAA500390701
Project Name: Mobilita Cannabinoidního receptoru CB1: role asociovaných proteinu 
Duration: 2007-2011
Project Investigator: J. Blahoš
Group: 14
Project Agency:   GA AS CR             
Project No.: IAA400400621
Project Name: DNA Condensation: Monte-Carlo Simulations, Light Scattering, Fluorescence Correlation Spectroscopy in vitro and in vivo  
Duration: 2006-2010
Project Investigator: J. Blahoš (co-investigator)
Group: 14
Project Agency:   FWEC 6           
Project No.: LSHM-CT-2004-511995  
Project Name: Synaptic scaffolding proteins orchestrating cortical synapse organisation during development  
Duration: 2005-2007
Project Investigator: J. Blahoš (co-investigator)
Group: 14
Project Agency:   GSF              
Project No.: 310/03/H147  
Project Name: Regulatory mechanisms of the immune responses and their potential for development of new preventive and therapeutic strategies
Duration: 2003-2007
Project Investigator: M. Lipoldová
Group: 15
Project Agency:   GSF              
Project No.: 310/06/1745
Project Name: Fine mapping and molecular identification of genes that control response to Leishmania major
Duration: 2006-2008
Project Investigator: M. Lipoldová
Group: 15
Project Agency:   GA AS CR             
Project No.: A500520606
Project Name: Mapping and Identification of Genes that Control Proliferation of Activated Lymphocytes and Study of their Relationship to Disease
Duration: 2006-2008 
Project Investigator: M. Lipoldová
Group: 15
Project Agency:   ME CR          
Project No.: LC06009  
Project Name: Centre for molecular ecology of vectors and pathogens 
Duration: 2006-2010 
Project Investigator: M. Lipoldová
Group: 15
Project Agency:   GSF              
Project No.: 204/07/0133
Project Name: Self-organization principles of non-membrane-bound organels in eukaryotic cells 
Duration: 2007-2009
Project Investigator: D. Staněk
Group: 16
Project Agency:   GSF              
Project No.: 301/05/0601 
Project Name: Assembly of small ribonucleoprotein particles in the cell nucleus
Duration: 2005-2007
Project Investigator: D. Staněk
Group: 16
Project Agency:   MPI           
Project No.: Partner group
Project Name: Pre-mRNA splicing and organization of the cell nucleus
Duration: 2006-2008
Project Investigator: D. Staněk
Group: 16
Project Agency:   GSF          
Project No.: 204/05/P510
Project Name: Interaction of Bacillus subtilis rRNA promoters with RNA polymerase: Defining elements required for regulation 
Duration: 2005-2007   
Project Investigator: L. Krásný
Group: 17
Project Agency:   IGA MH CR
Project No.: NR 9138-3/200
Project Name: Inhibitors of Bacterial RNA Polymerase Based on Nucleotide Analogues
Duration: 2007-2009
Project Investigator: L. Krásný
Group: 17
Project Agency:   FP6              
Project No.: 018094 (MACROCEPT)
Project Name: Targeted Therapies For Inflammatory Bowel Disease
Duration: 2005-2007  
Project Investigator: V. Holáň (co-investigator)
Group: 19
Project Agency:   IGA MH CR               
Project No.: NR8340
Project Name: Characterization and modulation of risk factors of human corneal grafts causing an immunological rejection
Duration: 2005-2007
Project Investigator: V. Holáň (co-investigator)
Group: 19
Project Agency:   GSF             
Project No.: 309/06/0121  
Project Name: Subcellular distribution of mu- and delta-opioid receptors and functional activity of trimeric G proteins after the long-term morphine stimulation
Duration: 2006-2008
Project Investigator: V. Holáň (co-investigator)
Group: 19
Project Agency:   GSF          
Project No.: 204/06/1658
Project Name: Putative role of Akt and PKC beta II in FAK-dependent migration or invasion of colorectal cancer cells  
Duration: 2006-2008  
Project Investigator: J. Turečková
Group: 20
Project Agency:   GSF         
Project No.: 204/07/1567 
Project Name: Tumor suppressors in the Wnt signaling pathway
Duration: 2007-2009  
Project Investigator: V. Kořínek
Group: 20
Project Agency:   ME CR            
Project No.: 2B06077
Project Name: High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer
Duration: 2006-2011 
Project Investigator: V. Kořínek
Group: 20
Project Agency:   GA AS CR             
Project No.: IAA5052406
Project Name: Analysis of haplotypes in wild and wild-derived mice on chromosome 17
Duration: 2004-2008
Project Investigator: Z. Trachtulec
Group: 21
Project Agency:   GSF        
Project No.: 301/05/0738 
Project Name: Identification and analysis of groups of conserved syntenic genes by methods of bioinformatics and molecular genetics
Duration: 2005-2007 
Project Investigator: Z. Trachtulec
Group: 21
Project Agency:   NHI            
Project No.: NIH-1R01 
Project Name: Consomic strains derived from C57/BL/6 and PWD
Duration: 2004-2007  
Project Investigator: J. Forejt
Group: 21
Project Agency:   GSF            
Project No.: 301/06/1334
Project Name: New mouse model of human aneuploidy syndromes
Duration: 2006-2008 
Project Investigator: J. Forejt
Group: 21
Project Agency:   EU       
Project No.: 037627 
Project Name: AnEUploidy understanding the importance of gene dosage imbalance in human health using genetics, functional genomics and systems biology   
Duration: 2007-
Project Investigator: J. Forejt
Group: 21
Project Agency:   GSF        
Project No.: 301/07/1264   
Project Name: Uncovering regulatory networks in novel mouse models by genetical genomics  
Duration: 2007-2009
Project Investigator: J. Forejt
Group: 21
Project Agency:   GSF         
Project No.: 301/07/1383  
Project Name: Gene expression profiling during mouse spermatogenesis: Implications for meiotic sex chromosome inactivation and gene retroduplication  
Duration: 2007-2009
Project Investigator: P. Jansa
Group: 21
Project Agency:   AS CR
Project No.: KAN200520701
Project Name: Nano-PCR - ultrasensitive test for detection of specific proteins in body fluids
Duration: 2007-2011
Project Investigator: Pe. Dráber
Group: 22
Project Agency:   Funding programme for projects of targeted research and development
Project No.: 1QS500520551
Project Name: New generation of preparations for amplifications of DNA fragments by polymerase chain reaction
Duration: 1.7.2005-2009
Project Investigator: M. Boubelík
Group: 22
Project Agency:   GSF             
Project No.: 301/06/0361 
Project Name: The regulatory role of NTAL in receptor-mediated signaling in mast cells
Duration: 2006-2008
Project Investigator: L. Dráberová
Group: 22
Project Agency:   IGA MH CR           
Project No.: NR8317-4  
Project Name: Regulatory mechanisms of growth and apoptosis of primary leukemia progenitor/stem cells
Duration: 2005-2008  
Project Investigator: L. Anděra (co-investigator)
Group: 23
Project Agency:   MPO          
Project No.: FT-TA2/015  
Project Name: Construction and large-scale production of recombinant proteins, derived from Epstaein-Barr virus nuclear antigen 1 (EBNA 1), and their application to the diagnostics of infectious diseasea
Duration: 2005-2007 
Project Investigator: L. Anděra (co-investigator)
Group: 23
Project Agency:   FP6 EU                                            
Project No.: STREP FP6-2003-NEST-PATH-2 12919 
Project Name: Human monoclonal antibodies from a library of hybridomas
Duration: 2005-2008
Project Investigator: V. Hořejší
Group: 24
Project Agency:   ME CR         
Project No.: EUREKA- 1P04OE 190 
Project Name: Recombinant signal proteins for generation of commercial interesting polyclonal and monoclonal antibodies 
Duration: 2005-2007   
Project Investigator: P. Angelisová
Group: 24
Project Agency:   ME CR            
Project No.: 1M0506
Project Name: Center of molecular and cellular immunology
Duration: 2005-2009  
Project Investigator: V. Hořejší
Group: 24
Project Agency:   ME CR      
Project No.: 2B06064
Project Name: New target genes for childhood leukemia diagnosis and treatment focused on adaptor molecules of signaling pathways
Duration: 2006-2011
Project Investigator: T. Brdička
Group: 24
Project Agency:   GSF              
Project No.: GD204/05/H023
Project Name: Molecular biology of differentiating cell
Duration: 2005-2009 
Project Investigator: P. Hozák
Group: 25
Project Agency:   ME CR             
Project No.: LC06063
Project Name: Flurescence microscopy in biological and medical research
Duration: 2006-2009 
Project Investigator: P. Hozák (J. Blahoš - co-investigator)
Group: 25
Project Agency:   ME CR        
Project No.: 2B06063
Project Name: Structure and irregularities of the nucleoskeleton: identification and diagnostics
Duration: 2006-2011
Project Investigator: P. Hozák
Group: 25
Project Agency:   AS CR       
Project No.: KAN200520704   
Project Name: New nanoparticles for ultrastructural diagnostics 
Duration: 2007-2011  
Project Investigator: P. Hozák
Group: 25
Project Agency:   GSF            
Project No.: 204/07/1592 
Project Name: Functions of nuclear myosin in gene expression
Duration: 2007-2009 
Project Investigator: P. Hozák
Group: 25
Project Agency:   GSF        
Project No.: DYN/05/E002  
Project Name: Control of stress and interferon regulated gene expression by transcription factors, histone modification and nuclear compartmentalization
Duration: 2005-2007 
Project Investigator: P. Hozák
Group: 25
Project Agency:   ME CR            
Project No.: LC545
Project Name: Functional Organisation of the Cell 
Duration: 2005-2009 
Project Investigator: P. Hozák
Group: 25
Project Agency:   GA AS CR              
Project No.: IAA500390501 
Project Name: The role of PML in cellular senescence 
Duration: 2005-2009
Project Investigator: Z. Hodný
Group: 25
Project Agency:   GSF                   
Project No.: 204/05/H023
Project Name: Molecular biology of differentiating cell
Duration: 2005-2008
Project Investigator: Pa. Dráber (co-investigator)
Group: 26
Project Agency:   GSF                   
Project No.: 204/05/2375
Project Name: Analysis and regulation of gamma-tubulin forms associated with membrane microdomains
Duration: 2005-2007
Project Investigator: Pa. Dráber
Group: 26
Project Agency:   FP6          
Project No.: INTAS 03  03-51-6459
Project Name: The functional role of microtubule phosphorylation in plant development and environmental stimuli response 
Duration: 2004-2007
Project Investigator: Pa. Dráber
Group: 26
Project Agency:   ME CR       
Project No.: 1P05ME776
Project Name: Participation in the action of Bioethic councils
Duration: 2005-2008
Project Investigator: V. Viklický
Group: 61
Project Agency:   ME CR       
Project No.: 1M06011
Project Name: The Centre of Molecular Methods for Monitoring the Diffuse Pollution of the Environment
Duration: 2006-2009
Project Investigator: J. Pěknicová
Group: 27
Project Agency:   GSF     
Project No.: 524/06/0817
Project Name: Ultrastructure, Energetic and Competition in Spermatozoa: A Comparative Study Using Two Model Species of Chondrostean and Teleostean Fishes
Duration: 2006-2008
Project Investigator: J. Pěknicová (co-investigator)
Group: 27
Project Agency:   ME CR             
Project No.: EUREKA E!3557 „EKDEQ“ OE211
Project Name: ELISA kits for detection of environmental quality 
Duration: 2006-2008
Project Investigator: J. Pěknicová (co-investigator)
Group: 27
Project Agency:   ME CR            
Project No.: 2B06151
Project Name: Biodegradation of polybrominated compounds, monitoring of concentration changes of pollutants and their intermediates in the environment
Duration: 2006-2011 
Project Investigator: J. Pěknicová (co-investigator)
Group: 27
Project Agency:   IGA MH CR    
Project No.: NR 8932
Project Name: Differential expression of Pregnancy Associated Plasma Protein - A (PAPP-A) and Insulin-like growth factor-binding protein 4 (IGFBP4) in follicular fluid and blood of women in correlation with ovarian hyperstimulation syndrome (OHSS)
Duration: 2006-2008
Project Investigator: J. Pěknicová (co-investigator)
Group: 27
Project Agency:   GA AS CR        
Project No.: IAA501110701
Project Name: Activity and silencing of mobile elements in mammalian cells
Duration: 2007-2009
Project Investigator: P. Svoboda
Group: 28
Project Agency:   EMBO   
Project No.: 1483
Project Name: EMBO Installation Project
Duration: 2007-2009
Project Investigator: P. Svoboda
Group: 28
Project Agency:   GA AS CR          
Project No.: A500520604
Project Name: Developmental Genetics of Amphioxus:Insight into Evolutionary Origin of Vertebrates
Duration: 2006-2010
Project Investigator: Z. Kozmik
Group: 29
Project Agency:   AS CR          
Project No.: KAN200520702
Project Name: Nanoimmunosensors for detection of cytokines
Duration: 2007-2011
Project Investigator: P. Šebo
Group: 30
Project Agency:   GSF               
Project No.: 203/05/2141
Project Name: Organic synthesis in protein crystals
Duration: 2005-2007
Project Investigator: J. Ondráček (co-investigator)
Group: 31
Project Agency:   ME CR          
Project No.: 1M0505
Project Name: Center of targeted therapeutic drugs
Duration: 2005-2009
Project Investigator: M. Fábry
Group: 31
Project Agency:   GSF             
Project No.: 301/07/0600
Project Name: Intersubunit complementation studies and characterization of genotype - phenotype correlations in adenylosuccinate lyase deficiency 
Duration: 2007-2009 
Project Investigator: J. Brynda (co-investigator)
Group: 31
Project Agency:   ME CR             
Project No.: OE210
Project Name: Engineering radionuclide - labeled antibodies
Duration: 2006-2009 
Project Investigator: J. Sedláček
Group: 31
Project Agency:   MPO
Project No.: 2A-2TP1/076
Project Name: Generic therapeutic antibodies
Duration: 2007-2011
Project Investigator: J. Sedláček
Group: 31
Project Agency:   GSF  
Project No.: 310/06/0477
Project Name: The role of NK and NKT cells in the development and pathogenesis of rheumatoid arthritis
Duration: 2006-2008
Project Investigator: Š. Růžičková
Group: 32
Project Agency:   ME CR           
Project No.: 1M0520
Project Name: Center for Applied Genomics
Duration: 2005-2009 
Project Investigator: V. Pačes
Group: 33
Project Agency:   ME CR        
Project No.: 2B06106
Project Name: Novel genomic and biotechlological approaches in molecular oncology: a way to the early diagnostics and targeted therapy
Duration: 2006-2011
Project Investigator: Č. Vlček
Group: 33
Project Agency:   GA AS CR          
Project No.: A500520602
Project Name: Cell death pathways in mesothelioma cells exposed to pharmacological and immunological inducers of apoptosis: genomic and proteomic approach
Duration: 2006-2008
Project Investigator: J. Neužil
Group: 34
Project Agency:   GA AS CR      
Project No.: IAA500520702
Project Name: A novel model of apoptosis initiation by "mitocans"
Duration: 2007-2009
Project Investigator: J. Neužil
Group: 34
Project Agency:   AS CR        
Project No.: KAN200520703 
Project Name: The use of ultrasound in nanomedicine
Duration: 2007-2011
Project Investigator: J. Neužil
Group: 34
Project Agency:   GSF     
Project No.: 305/07/1008 
Project Name: Role of mitochondria in cardiomyocyte apoptosis during myocardial infarction: from cells to the whole animal
Duration: 2007-2009
Project Investigator: J. Neužil
Group: 34
Project Agency:   GSF      
Project No.: 303/06/0895
Project Name: Characterization of proteins secreted by the male reproductive tract and their role in individual steps of the reproduction process
Duration: 2006-2008
Project Investigator: V. Jonáková
Group: 35
Project Agency:   GSF   
Project No.: 204/03/H066 
Project Name: Molecular mechanisms of cell interactions
Duration: 2003-2007  
Project Investigator: M. Dvořák
Group: 36
Project Agency:   GSF         
Project No.: 204/06/1728 
Project Name: Bone marrow microenvironment in the development of monoblastic leukaemia
Duration: 2006-2008
Project Investigator: M. Dvořák
Group: 36
Project Agency:   GSF            
Project No.: 203/06/1038
Project Name: Supramolecular approach to saccharide-mediated cell surface recognition
Duration: 2006-2008  
Project Investigator: J. Králová (co-investigator)
Group: 36
Project Agency:   GA AS CR        
Project No.: A500520608 
Project Name: Protein transduction as a tool to study a function of Myb proteins
Duration: 2006-2008
Project Investigator: M. Dvořák
Group: 36
Project Agency:   ME CR       
Project No.: LC06061
Project Name: Center of Cell Invasiveness in Embryonic Development and Tumour Metastases
Duration: 2006-2010   
Project Investigator: M. Dvořák
Group: 36
Project Agency:   AS CR          
Project No.: KAN200200651   
Project Name: Nanoparticulate and supramolecular systems for targeted drug delivery
Duration: 2006-2010
Project Investigator: J. Králová (co-investigator)
Group: 36
Project Agency:   ME CR        
Project No.: LC06077
Project Name: Center of Chemical Genetics
Duration: 2006-2010
Project Investigator: P. Bartůněk
Group: 38
Project Agency:   FP6 EU         
Project No.: 018652 CRESCENDO
Project Name: Consortium for Research into Nuclear Receptors in Development and Aging   
Duration: 2006-2011 
Project Investigator: P. Bartůněk
Group: 38
Project Agency:   GA AS CR        
Project No.: IAA500520705
Project Name: Characterization of the new member of sterol-sensing-domain protein family and its role in lipid metabolism
Duration: 2007-2009
Project Investigator: M. Zíková
Group: 38
Project Agency:   GA AS CR         
Project No.: B500520601   
Project Name: Quantification and localization of maternal mRNAs in early development of Xenopus
Duration: 2006-2007 
Project Investigator: R. Šindelka
Group: 39


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