Department of Teratology

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Head: Assoc. Prof. Miroslav Peterka, MD, DSc

E-mail: peterka

biomed [dot] cas [dot] cz

Phone: +420 241 062 604

Laboratory of Embryogenesis

Assoc. Prof. Miroslav Peterka, MD, DSc | Head of Laboratory

E-mail: peterka

biomed [dot] cas [dot] cz

Phone: +420 241 062 604

Miroslav Peterka, MD, DSc | Research Scientist

Zbyněk Likovský, PhD | Research Scientist

Petra Herlová, MSc | PhD Student

Natalie Hrozinková, MSc | PhD Student

Bronislava Rokytová | Technician

Ivana Koppová | Technician

Laboratory of Odontogenesis

Renata Peterková, MD, PhD | Head of Laboratory

E-mail: repete

biomed [dot] cas [dot] cz

Phone: +420 241 062 232

Renata Peterková, MD, PhD | Research Scientist

Maria Hovořáková, PhD | Research Scientist

Svatava Churavá, MSc | PhD Student

Jan Procházka, MSc | PhD Student

Michaela Rothová, MSc | PhD Student

Zdenka Lisá | Technician

Lucie Smrčková | Undergraduate Student

Research topics

The Department of Teratology focuses on experimental and clinical teratology with the aim of contributing to our knowledge of normal and pathological development, the ethiopathogenesis of developmental anomalies, and possibilities for their prevention. Only a small portion of inborn defects in man can be explained either by prenatal exposure to a harmful external factor (15 % of cases) or by genetic reasons (20 % of cases). Most developmental defects (65 %) are thought to result from prenatal exposure to the combined effect of several sub-threshold doses of external factors that act either simultaneously or sequentially; a genetic predisposition is presumed in some of these cases. In the Department, the causes and mechanisms that are responsible for the origin of developmental defects induced by environmental and/or genetic factors are investigated. In these studies, two experimental models are used (developing chick embryo and developing mouse dentition), as well as a clinical/epidemiological approach. The origin of external malformations, especially of orofacial clefts, is a pivotal research topic of the Laboratory of Embryogenesis (M. Peterka). The Laboratory of Odontogenesis (R. Peterkova) focuses on tooth development under normal, pathological, and experimental conditions.