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Grant projects implemented at IMG in 2010

    2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012

GRANT AGENCY

GRANT´S NUMBER

THE GRANT´S NAME

SOLUTION TIME

GRANT´S
CO-ORDINATOR

GROUP

ME CR

OE08011

Superfine defined diets for laboratory animals designed on natural components - development, innovation,and plant tests

2008-2010

Pe. Dráber (M. Boubelík) (co-investigator)

 22

 EU FP6 018933   Clinigene European clinical Gene Transfer Advisory Network  2005-2011   J. Bubeník

GA AS CR

IAA500520807

Mechanisms of protective immunity against tumours with different expression of immunodulatory molecules

2008-2010

M. Indrová

11

GSF

GA301/07/1410

Immunosuppressive cell populations in the course of tumour progression and therapy.

2007-2011

M. Reiniš

11

GSF

GA301/09/1024

Molecular and cellular mechanisms of tumour chemotherapy: immunomodulatory effects

2009-2011

M. Indrová

11

MZ ČR

NS10660_3/2009

Development of experimental anti-WT 1 vaccine for immunotherapy of tumours

2009-2011

M. Indrová (co-investigator)

11

GSF

P301/10/2174

Epigenetic mechanisms in regulativ of genes important for antigen presentation and antitumour immunity

2010-2013

M. Reiniš

11

EU

037377

Engineering of the porcine genome for xenotransplantation studies in primates: a step towards clinical application

2006-2011

J. Hejnar

12

GSF

GP204/08/P616

The role of DNA methylation and histone modifications in the establishment and maintenance of HIV-1 latency

2008-2010

J. Blažková 

12

GSF

GA301/09/P667

Transcriptional silencing of retroviral vectors during their integration into the host genome

2009-2011

F. Šenigl

12

GSF

GA301/09/2031

Fuzogenic  envelope glycoproteins of human endogenous retroviruses and thein receptors

2009-2011

J. Hejnar

12

GSF

P502/10/1651

Characterization of new avian sarcoma and leukosis virus (ASLV) receptor alleles as revealed by the analysis of semiresistant cells

2010-2012

J. Plachý

12

GA AS CR

IAA500520707

The role of innate immune molecules in embryonic homeostasis and sterile inflammation

2007-2011

D. Filipp

13

GSF

GA310/09/2084

Characterization of the molecular machinery regulating the recruitment of signaling molecules to lipid rafts

2009-2013

D. Filipp

13

ME CR

2B08066

Novel treatment of genetically determined metabolic disease, type 1 diabetes, using an immunotherapeutical approach.

2008-2011

D. Filipp

13

GA AS CR

IAA500390701

Role of proteins associated with Cannabinoid receptor CB1 in trafficking

2007-2011

J. Blahoš

14

GA AS CR

IAA400400621

DNA Condensation: Monte-Carlo Simulations, Light Scattering, Fluorescence Correlation Spectroscopy in vitro and in vivo

2006-2010

J. Blahoš (co-ordinator)

14

GSF

GA303/08/1591

Study of glutamate receptors conformational changes using novel fluorescent techniques

2008-2012

J. Blahoš

14

GSF

GA310/08/1697

First genetic model for analysis of susceptibility to parasite Leishmania tropica: potential implications for studies of human leishmaniases

2008-2012

M. Lipoldová

15

ME CR

LC06009

Centre for molecular ecology of vectors and pathogens

2006-2010

M. Lipoldová

15

AS CR

KAN200520801

Targeted expression and transport of bioactive molecules

2008-2012

D. Staněk

16

GSF

P305/10/0424

Regulation of alternative splicing via chromatin acetylation

2010-2013

D. Staněk

16

  EU FP6   LSHP-CT-2007-037693   HIV protease inhibitor resistance by enzyme-substrate coevolution   2007-2011   R. Sedláček

GA AS CR

IAA500520812

Investigating the pathologic role of metalloproteinases in liver using transgenic mice with conditional expression of transgenes

2008-2012

R. Sedláček

18

GSF

GC301/08/J053

Mouse models for investigation of biological functions of novel Kazal-type protease inhibitors LEKTI-2 and LEKTI-3

2008-2010

R. Sedláček

18

GSF

P305/10/2143

Generation of mouse models for targeting stelete cells and myofibroblasts in the liver

2010-2013

R. Sedláček

18

GSF

P303/10/2044

The Impact of a liver-specific deficiency of growth factor sheddase ADAM10 on liver development and pathology

2010-2013

M. Jiroušková

18

AS CR

KAN200520804

Biocompatible nanofiber scaffolds forming novel drug matrices for the application of biologically and pharmacologically active substances

2008-2012

V. Holáň

 

19

EU – FP7

222509

KINACEPT-Novel anti-inflammatory compounds for autoimmune diseases

2008-2010

V. Holáň (co-investigator)

19

GSF

GD310/08/H077

Regulation of immunological mechanisms in health and disease:Development of new diagnostic and therapeutic approaches

2008-2011

V. Holáň (co-investigator.)

19

GSF

GA206/08/0640

Host-parasite relationship, hybrid zone, immune systém, house mouse, Mus musculus

2008-2012

V. Holáň (co-investigator)

19

GSF

GA204/07/1567

Tumor suppressors in the Wnt signaling pathway

2007-2010

V. Kořínek

20

ME CR

2B06077

High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer

2006-2011

V. Kořínek

20

GSF

P305/10/1931

Identification of interactors of the meiotic histone methyltransferase Hybrid sterility 1 /PR-domain 9)

2010-2013

Z. Trachtulec

21

  EU FP6   LSH-CT-2006-037627   AnEUploidy: understanding gene dosage imbalance in human health using genetics, functional genomics and system biology   2006-2010   J.Forejt
  AS CR   Premium Academiae   Premium Academiae  2007-2013   J. Forejt

AS CR

M200520901

Novel components of mast cell immune receptor signalling

2009-2012

Pe. Dráber

22

AS CR

KAN200520701

Nano-PCR – ultrasenzitivní test detekce specifických proteinů v tělních tekutinách

2007-2011

Pe. Dráber

22

GSF

GA301/09/1826

Topography and function of         Csk-binding proteins of the plasma membrane in mast cells 

2009-2013

Pe. Dráber

22

GSF

P302/10/1759

Function-structure relationships between transmembrane adaptor-based signalosomes in mast cells

2010-2013

L. Dráberová

22

AS CR

KAN200520703

The use of ultrasound in nanomedicine

2007-2011

L. Anděra (co-investigator)

23

MH CR

NS10287-3/2009

Experimental therapy of mantle cell lymphoma (Mantle Cell Lymphoma, MCL)

2009-2011

L. Anděra (co-investigator)

23

GA AS CR

KJB500520801

Dissection of Bid function in TRAIL-induced apoptosis

2008-2010

M. Koc

 

23

GSF

P301/10/1971

Expression, signaling and function of Death Receptors in human embryonic stem cells

2010-2012

L. Anděra

23

GSF

MEM/09/E011

Signaling and adaptor proteins of leukocyte membrane microdomains

2009-2012

V. Hořejší

24

ME CR

1M0506

Center of Molecular and Cellular Immunology

2005-2011

V. Hořejší

24

ME CR

2B06064

New target genes for childhood leukemia diagnosis and treatment focused on adaptor molecules of signaling pathways

2006-2011

T. Brdička

24

AS CR

KAN200520704

New nanoparticles for ultrastructural diagnostics

2007-2011

P. Hozák

25

GSF

GA204/07/1592

Functions of nuclear myosin in gene expression

2007-2011

P. Hozák

25

GSF

GA204/09/H084

Molecular biology of a  differentiating cell

2009-2012

P. Hozák

25

  ME CR   LC545   Functional organisation of the cell   2005-2010   P. Hozák
  ME CR   ME09101   Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus   2009-2010   P. Hozák

ME CR

2B06063

Flurescence microscopy in biological and medical research

2006-2011

P. Hozák

25

GSF

GA204/09/1777

Analysis of signaling assemblies containing gamma-tubulin

2009-2011

Pa. Dráber

26

GSF

P302/10/1701

Analysis of functional differences between gamma-tubulins

2010-2012

E. Dráberová

26

GSF

GA204/09/0085

RNA silencing and long dsRNA in mammalian cells

2009-2013

P. Svoboda

28

ME CR

ME09039

Role of posttranslational mechanisms in reprogramming mouse oocytes to pluripotent cells.

2009-2012

P. Svoboda

28

GSF

P305/10/2215

Control of chromatin and pluripotency by microRNAs

2010-2013

P. Svoboda

28

GA AS CR

IAA500520604

Developmental Genetics of Amphioxus:Insight into Evolutionary Origin of Vertebrates

2006-2010

Z. Kozmik

29

GA AS CR

IAA500520908

Význam genů Pax v evoluci oka

2009-2013

Z. Kozmik

29

GSF

GD204/09/H058

Intercellular signalling in development of the organism and in disease genesis

2009-2012

Z. Kozmik (co-investigator)

29

GSF

GA204/08/1618

Molecular basis of canonical Wnt signalling during eye and brain development

2008-2010

Z. Kozmik

29

  P305/10/J064   Reconstructing urbilaterian photoreceptors: comparative study between Branchiostoma (Chordata) and Platynereis (Annelida)   2010-2012   Z. Kozmik (co-investigator)  29

GSF

GA203/09/0820

Structurally inspired synthese of the selectiv inhibitors nukleotidas, potentially important medicals

2009-2013

J. Brynda

31

MIT

2A-2TP1/076

Generic therapeutic antibodies

2007-2011

J. Sedláček

31

  ME CR   1M0505   Center of targeted therapeutic drugs   2005-2011   M. Fábry (co-investigator)   31

ME CR

1M6837805002

Center for Applied Genomics

2005-2011

V. Pačes

33

ME CR

2B06106

Novel genomic and biotechlological approaches in molecular oncology: a way to the early diagnostics and targeted therapy

2006-2011

Č. Vlček

33

ME CR

2B08031

Metagenomics and bioinformatics as a basis for preparation of effective
approaches, preparation and  characterization of microorganisms and their consortia for utilization in bioremediation

 

2008-2011

J. Pačes

33

GSF

P305/10/J052

Functional analysis of endogenous retroviral elements in human genome: possible association with cancers

2010-2012

J. Pačes

33

AS CR

KAN200200651

Nanoparticulate and supramolecular systems for targeted drug delivery

2006-2010

J. Králová (co-investigator)

36

GSF

GA203/09/1311

Synthetic probes for recognition of tumor markers: applications for cell directed apoptosis and targeted photodynamic therapy

2009-2012

J. Králová

36

GSF

GA301/09/1727

Large-scale identification of genes responsible for the formation of solid tumours

2009-2012

M. Dvořák

36

ME CR

LC06061

Center of Cell Invasiveness in Embryonic Development and Tumour Metastases

2006-2010

M. Dvořák

36

GSF

P305/10/2133

Studium migrace satelitních buněk

2010-2012

P. Kašpar

36

GSF

GA204/08/1418

The role of the JAK/STATsignalling pathway in cellular senescence

2008-2012

Z. Hodný

 

37

GSF

GA301/08/0353

Protein modifications in DNA damage signalling: Mechanisms and cancer relevance

2008-2010

J. Bartek

 

37

  GSF   P301/10/1525   Mechanisms of DNA damage checkpoint termination
  2010-2012   J. Bartek

GSF

GA204/08/1418

The role of the JAK/STAT signalling pathway in cellular senescence

2008-2012

Z. Hodný

 

37

GSF

P305/10/P420

Role of Wip1 phosphatase in the DNA damage response

2010-2012

L. Macůrek

37

FP7 EU

TRIREME 223575

Systems-Level, Multi-Layer Understanding of Cellular Responses to Ionizing Radiation

2009-2012

J. Bartek

38

FP6 EU

018652 CRESCENDO

Consortium for Research into Nuclear Receptors in Development and Aging

2006-2011

P. Bartůněk

38

GSF

GA310/08/0878

The role of the cells prion protein in erytroidnic differentiation

2008-2012

P. Bartůněk (co-investigator)

38

GSF

GA204/09/1905

Disp3: A potential role in the self renewal and differentiation of neural stem cells

2009-2012

P. Bartůněk

38

ME CR

LC06077

Center of Chemical Genetics

2006-2010

P. Bartůněk

38

GSF

P305/10/0953

New regulators of megakaryocyte and erythroid lineage commitment

2010-2013

P. Bartůněk

38

 

GSF

GA204/09/0565

Role of  RECQ5 DNA helicase in maintenance of genomic stability

2009-2013

P. Janščák

42

GSF

P305/10/0281

Role of the Rothmund-Thomson syndrome gene product in maintenance of genomic stability

2010-2014

P. Janščák

42


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