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Education |
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1999-2004 |
Ph.D. in Molecular Biology and Virology (thesis "HIV-1 Protease Inhibition and Drug Resistance Studied by Structure Analysis and Computational Methods"), Faculty of Science, Charles University, Prague, Czech Republic. |
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Oct - Nov 2001 |
crystallographic refinement, J. R Mesters, Prof. R. Hilgenfeld, Institut für Molekulare Biotechnologie, Jena, Germany |
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Jul 2001 |
summer school of quantum chemistry, Dr. P. Nachtigall, Prof. P.Hobza, J. Heyrovsky Institute of Physical Chemistry, Prague |
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Dec 2000 |
course on Combinatorial Chemistry, S. Miertus, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy |
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Jul 2000 |
course on biomolecular simulations, R. Wade, M. Nilges, European Molecular Biology Laboratories (EMBL), Heidelberg |
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Nov 1999 |
computational “WHAT IF“ user course, G. Vriend, EMBL, Heidelberg |
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1994-1999 |
MSc. in biology, molecular biology, virology, genetics and immunology, Faculty of Science, Charles University, Prague, Czech Republic. |
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Experience |
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Jan 2010 – present |
researcher at the group of Prof. Pavel Hobza, Institute of Organic Chemistry and Biochemistry AS CR v.v.i., Prague |
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2007 – 2009 |
post-doc with Dr. Lubomír Rulíšek and Dr. Jan Konvalinka, IOCB, Prague |
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Jan - Dec 2006 |
post-doc with Dr. Martin J. Field, Institut de Biologie Structurale, Grenoble |
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2004 -2005 |
post-doc with Prof. Pavel Hobza, IOCB, Prague |
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Research interest |
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drug design
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biomolecular simulations
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borane chemistry
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noncovalent interactions
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reaction mechanisms
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X-ray crystallography
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