|
GRANT
AGENCY
|
GRANT´S NUMBER
|
THE GRANT´S NAME
|
SCHEDULE
|
GRANT´S
CO-ORDINATOR
|
GROUP
|
|
GA ČR
|
GAP301/10/2174
|
Epigenetic
mechanisms in regulativ of genes important for antigen
presentation
and
antitumour immunity
|
2010-2013
|
M.
Reiniš
|
11
|
|
GA ČR
|
GPP301/11/P220
|
Mechanisms
underlying cyclophosphamide-induced accumulation of myeloid
derived
suppressor cells
|
2011-2013
|
R.
Mikyšková
|
11
|
|
GA ČR
|
GAP502/10/1651
|
Characterization of new avian sarcoma and
leukosis virus (ASLV) receptor
alleles as revealed by the analysis of
semiresistant cells
|
2010-2012
|
J.
Plachý
|
12
|
|
GA ČR
|
P502/11/2207
|
Avian
Sarcoma and Leukosis Virus-based Vectors and Their Potential for
Transgenesis in chicken
|
2011-2013
|
J.
Hejnar
|
12
|
|
GA ČR
|
GAP304/12/1736
|
Development of CpG methylation of HIV-1
promoter and its stabilizing effect on the latent provirus reservoir:
longitudinal study in patients
|
2012-2014
|
K.
Trejbalová
|
12
|
|
MŠMT
|
LK11215
|
Regulation of active endogenous retroviruses in the
mammalian genome
|
2012-2016
|
D.
Elleder
|
12
|
|
MZE
|
QJ1210041
|
A novel type of vaccine for attenuation of viral diseases
in poultry
|
2012-2016
|
J.
Hejnar
(spoluřeš.)
|
12
|
|
GA ČR
|
GA310/09/2084
|
Characterization of the molecular machinery
regulating the recruitment
of signaling molecules to lipid rafts
|
2009-2013
|
D.
Filipp
|
13
|
|
GA ČR
|
P302/12/G101
|
Molecular mechanisms of leukocyte receptor signalling
– their role in health and disease
|
2012-2018
|
V.
Hořejší (+ Pe. Dráber
+ D.
Filipp)
|
13
|
|
GA ČR
|
GA303/08/1591
|
Study of glutamate receptors conformational
changes using novel fluorescent techniques
|
2008-2012
|
J.
Blahoš
|
14
|
|
GA ČR
|
GAP303/12/2408
|
Functional
consequences of metabotropic glutamate receptor 1a and 1b splice
variants assebmly in heterodimeric complexes
|
2012-2016
|
J.
Blahoš
|
14
|
|
GA ČR
|
GA310/08/1697
|
First
genetic model for analysis of susceptibility to parasite Leishmania
tropica: potential implications for studies of human leishmaniases
|
2008-2012
|
M.
Lipoldová
|
15
|
|
GA ČR
|
GAP502/11/2116
|
Differences
in clinical course of tick-borne encephalitis in host, and their
genetic determination
|
2011-2015
|
M.
Lipoldová (spoluřeš.)
|
15
|
|
MŠMT
|
LH12049
|
New genomic strategy for fast identification of genes
controlling development of infectious diseases and cancer
|
2012-2015
|
M.
Lipoldová
|
15
|
|
AV ČR
|
KAN200520801
|
Targeted
expression and transport of bioactive molecules
|
2008-2012
|
D.
Staněk
|
16
|
|
GA ČR
|
GAP305/10/0424
|
Regulation of alternative splicing via
chromatin acetylation
|
2010-2013
|
D.
Staněk
|
16
|
|
GA ČR
|
GAP302/11/1910
|
Formation
of splicing machinery in the context of the cell nucleus
|
2011-2014
|
D.
Staněk
|
16
|
|
GA ČR
|
P305/12/G034
|
Centre for RNA biology
|
2012-2018
|
D.
Staněk
(+ Pe. Svoboda) (spoluřeš.)
|
16
|
|
GA ČR
|
GPP301/12/P425
|
Functional
analysis of hBrr2 mutations linked to retinitis pigmentosa
|
2012-2014
|
Z.
Cvačková
|
16
|
|
GA AV ČR
|
IAA500520812
|
Investigating
the pathologic role of metalloproteinases in liver using transgenic
mice with conditional expression of transgenes
|
2008-2012
|
R.
Sedláček
|
18
|
|
GA ČR
|
GAP305/10/2143
|
Generation
of mouse models for targeting stelete cells and myofibroblasts in the
liver
|
2010-2013
|
R.
Sedláček
|
18
|
|
GA ČR
|
GAP303/10/2044
|
The
Impact of a liver-specific deficiency of growth factor sheddase ADAM10
on liver development and pathology
|
2010-2013
|
R.
Sedláček
|
18
|
|
GA ČR
|
GAP302/11/2048
|
Function
of metalloproteinases in colon epithelium and during development of
experimental colitis and colon cancer
|
2011-2014
|
R.
Sedláček
|
18
|
|
OPVK
|
CZ.1.07/2.3.00/20.0102
|
Formation of an expert phenogenomics team
|
2011-2014
|
R.
Sedláček
|
18
|
|
OPVK
|
CZ.1.07/2.3.00/30.0027
|
Establishment of a centre of transgenic technologies
|
|
R.
Sedláček
|
18
|
|
MŠMT
|
Rada
pro velké infrastruktury pro
výzkum,
vývoj a inovace
|
Infrafrontier-CZ/Czech Centre for Phenogenomics as a
national centre of the “European Infrastructure for Phenotyping
and Archiving Model Mammalian Genomes”: Integration of the Czech
national centre into the international network – support of
international activities
|
2012-2015
|
R.
Sedláček
|
18
|
|
MŠMT
|
LK11213
|
Analysis of the Pin1 and CRMP2A genes and their impact on
the growth, branching and regeneration of axons in vitro and in vivo
|
2012-2016
|
M.
Balaštík
|
18
|
|
AV ČR
|
KAN200520804
|
Biocompatible
nanofiber scaffolds forming novel drug matrices for the application of
biologically and pharmacologically active substances
|
2008-2012
|
V.
Holáň
|
19
|
|
GA ČR
|
GA206/08/0640
|
Host-parasite relationship, hybrid zone,
immune systém, house mouse, Mus musculus
|
2008-2012
|
V.
Holáň (spoluřeš.)
|
19
|
|
GA ČR
|
GAP304/11/0653
|
Targeted
differentiation and transdifferentiation of limbal and mesenchymal stem
cells and their therapeutic applications in preclinical models
|
2011-2014
|
V.
Holáň
|
19
|
|
GA ČR
|
GAP301/11/1568
|
Cellular
aspects of transplantation tolerance
|
2011-2014
|
V.
Holáň (spoluřeš.)
|
19
|
|
GA ČR
|
GAP305/11/1780
|
Wnt
signaling in self-renewal and tumorigenesis of the intestinal epithelia
|
2011-2014
|
V.
Kořínek
|
20
|
|
GA ČR
|
GAP304/11/1252
|
Bacteria
in etiology, prevention ant therapy of experimentally induced
intestinal inflammation and colon cancer
|
2011-2014
|
V.
Kořínek (spoluřeš.)
|
20
|
|
GA ČR
|
GAP305/12/2347
|
HIC1,
Hypermethylated in cancer 1, gene targeting, tumors, expression
prifiling, cellular signaling
|
2012-2015
|
V.
Kořínek
|
20
|
|
MPO
|
TIP
– FR-TI4/802
|
Development of novel chemical
compounds that can be utilised in antitumour therapy and regenerative
medicine
|
2012-
|
P.
Bartůněk (+ V. Kořínek)
|
20
|
|
GA ČR
|
GD204/09/H058
|
Intercellular
signalling in development and disease
|
2009-2012
|
Z.
Kozmik (spoluřeš.)
(+
Kořínek)
|
20
|
|
AV ČR
|
Premium Academiae
|
Premium Academiae
|
2007-2013
|
J.
Forejt
|
21
|
|
GA ČR
|
GAP305/10/1931
|
Identification of interactors of the meiotic
histone methyltransferase Hybrid sterility 1 /PR-domain 9)
|
2010-2013
|
Z.
Trachtulec
|
21
|
|
MŠMT
|
LD11079 (COST CZ)
|
New mouse models for the study
of biomedical complex traits and human diseases for systemic genetics
|
2011-2014
|
J.
Forejt
|
21
|
|
GA ČR
|
GPP305/11/P630
|
Epigenetic
regulators of gene expression in mouse spermatogenesis
|
2011-2013
|
O.
Mihola
|
21
|
|
GA ČR
|
GD204/09/H084
|
Molecular
biology of a differentiating cell
|
2009-2012
|
P.
Hozák (+ J. Forejt + Pe. Dráber + Pa. Dráber)
|
21
|
|
AV ČR
|
M200520901
|
Novel
components of mast cell immune receptor signalling
|
2009-2012
|
Pe.
Dráber
|
22
|
|
MPO
|
FR-TI3/067
|
Genetically
modified polymerases and their utilization for amplification of
non-purified DNA
|
2011-2014
|
Pe.
Dráber
|
22
|
|
GA ČR
|
GA301/09/1826
|
Topography and function of Csk-binding
proteins of the plasma membrane in mast cells
|
2009-2013
|
Pe.
Dráber
|
22
|
|
TA ČR
|
TA01010436
|
New
generations of DNA aptamers
|
2011-2013
|
Pe.
Dráber
|
22
|
|
GA ČR
|
GAP302/10/1759
|
Function-structure
relationships between transmembrane adaptor-based signalosomes in mast
cells
|
2010-2013
|
L.
Dráberová
|
22
|
|
MŠMT
|
COST – LD12073
|
Membrane signalosomes of mast cells and basophiles – targets for innovative therapy
|
2012-2014
|
Pe.
Dráber
|
22
|
|
GA ČR
|
P302/12/G101
|
Molecular mechanisms of leukocyte receptor signalling
– their role in health and disease
|
2012-2018
|
V.
Hořejší (+ Pe. Dráber + D. Filipp)
|
22
|
|
GA ČR
|
GD204/09/H084
|
Molecular
biology of a differentiating cell
|
2009-2012
|
P.
Hozák (+ J. Forejt + Pe. Dráber + Pa. Dráber)
|
22
|
|
GA ČR
|
GAP301/10/1971
|
Expression, signaling and function of Death
Receptors in human embryonic stem cells
|
2010-2012
|
L.
Anděra
|
23
|
|
MŠMT
|
LH12202
|
Analysis and inhibition of the mechanisms leading to
resistance of tumour cells to the TRAIL ligand
|
2012-2015
|
L.
Anděra
|
23
|
|
MZ ČR
|
NT/13201
|
Role of angiogenesis in the survival, growth,
dissemination and therapeutic response of mantle cell lymphoma (MCL)
|
2012-2015
|
L.
Anděra (spoluřeš.)
|
23
|
|
GA ČR
|
GEMEM/09/E011
|
Signaling
and adaptor proteins of leukocyte membrane microdomains
|
2009-2012
|
V.
Hořejší
|
24
|
|
GA ČR
|
GAP305/11/0459
|
The effect of transmembrane domains of
integral proteins on dynamic organisation of the plasma membrane of T
lymphocytes
|
2011-2014
|
T.
Brdička (spoluřeš.)
|
24
|
|
GA ČR
|
GAP302/12/1712
|
Function
of Csk-anchoring proteins SCIMP and PSTPIP2 in leukocyte signaling and
inflammation
|
2012-2015
|
T.
Brdička
|
24
|
|
GA ČR
|
P302/12/G101
|
Molecular
mechanisms of signaling through leukocyte receptors their role in
health and disease
|
2012-2018
|
V.
Hořejší (+ Pe. Dráber
+ D.
Filipp)
|
24
|
|
MZ ČR
|
NT/13271
|
Phenotyping of T- and B- lymphocytes in immunodeficient
patients
|
2012-2015
|
T.
Brdička (spoluřeš.)
|
24
|
|
MZ ČR
|
NT/13462
|
Optimization of immunotherapy and monitoring of minimal
residual disease using flow cytometry in resistant acute lymphoblastic
leukaemia
|
2012-2015
|
P.
Otáhal (spoluřeš.)
|
24
|
|
GA ČR
|
GD204/09/H084
|
Molecular
biology of a differentiating cell
|
2009-2012
|
P.
Hozák
|
25
|
|
GA ČR
|
GAP305/11/2232
|
Functions
of myosin I and its binding partners in the cell nucleus
|
2011-2015
|
P.
Hozák
|
25
|
|
TA ČR
|
TE01020118
|
Electron microscopy
|
2012-2019
|
P. Hozák (spoluřeš)
|
25
|
|
MPO
|
FR-TI3/588
|
Development of a kit for detection of
mutations in structural proteins of a cell
|
2011-2015
|
P.
Hozák
|
25
|
|
EU
– FP7
|
262023
|
Euro-BioImaging:
Research infrastructure for imaging technologies in biological and
biomedical sciences
|
2011-2013
|
P.
Hozák
|
25
|
|
MPO
|
FR-TI4/660
|
Multimodal holographic microscope
|
2012-2014
|
P.
Hozák (spoluřeš.)
|
25
|
|
MŠMT
|
LD12063
|
New nuclear functions of central filaments
|
2012-2015
|
P.
Hozák
|
25
|
|
MŠMT
|
LG12017
|
Provision of participation in the managing organs of the
European and World Microscopy Society (EMS, IFSM)
|
2012-2015
|
P.
Hozák
|
25
|
|
MŠMT
|
LE12004
|
Support of the Czech participation in pan-European
research infrastructure Euro-Bioimaging
|
2012-2015
|
P.
Hozák
|
25
|
|
MŠMT
|
LH12143
|
Contribution of actin and myosin protein families to
chromatin dynamics and transcription in the cell nucleus
|
2012-2015
|
P.
Hozák
|
25
|
|
GA ČR
|
GAP302/10/1701
|
Analysis
of functional differences between gamma-tubulins
|
2010-2012
|
E.
Dráberová
|
26
|
|
GA ČR
|
GPP302/11/P709
|
Analysis
of microtubular changes during activation of mast cells
|
2011-2013
|
V.
Sulimenko
|
26
|
|
GA ČR
|
GAP302/12/1673
|
Role of
gamm-tubulin complexes in regulation of cell cycle progression
|
2012-2015
|
Pa.
Dráber
|
26
|
|
GA ČR
|
GD204/09/H084
|
Molecular
biology of a differentiating cell
|
2009-2012
|
P.
Hozák (+ J. Forejt + Pe. Dráber + Pa. Dráber)
|
26
|
|
TACR
|
TA01010436
|
New generations of DNA aptamers
|
2011-2013
|
Pe.
Dráber (+ Pa. Dráber)
|
26
|
|
MŠMT
|
LH12050
|
Regulation of microtubule formation in brain tumour cells
|
2012-2015
|
Pa.
Dráber
|
26
|
|
GA ČR
|
GA204/09/0085
|
RNA
silencing and long dsRNA in mammalian cells
|
2009-2013
|
P.
Svoboda
|
28
|
|
GA ČR
|
GAP305/10/2215
|
Control
of chromatin and pluripotency by microRNAs
|
2010-2013
|
P.
Svoboda
|
28
|
|
MŠMT
|
ME09039
|
Role of
posttranslational mechanisms in reprogramming mouse oocytes to
pluripotent cells.
|
2009-2012
|
P.
Svoboda
|
28
|
|
GA ČR
|
P305/12/G034
|
Centre for RNA biology
|
2012-2018
|
D.
Staněk (+ Pe. Svoboda) (spoluřeš.)
|
28
|
|
GA AV ČR
|
IAA500520908
|
The role of Pax genes in eye evolution
|
2009-2013
|
Z.
Kozmik
|
29
|
|
GA ČR
|
GD204/09/H058
|
Intercellular
signalling in development of the organism and in disease genesis
|
2009-2012
|
Z.
Kozmik (spoluřeš.)
|
29
|
|
GA ČR
|
GAP301/11/2198
|
Genetics
of mammalian eye development
|
2011-2014
|
Z.
Kozmik
|
29
|
|
GA ČR
|
GAP305/10/2141
|
Evolution of photoreceptors: insights from
ancestral regulatory circuits
|
2010-2014
|
Z.
Kozmik
|
29
|
|
GA ČR -
Eurocores
|
GCP305/10/J064
|
Reconstructing urbilaterian photoreceptors:
comparative study between Branchiostoma (Chordata) and Platynereis
(Annelida)
|
2010-2012
|
Z.
Kozmik (spoluřeš.)
|
29
|
|
GA ČR
|
GAP305/12/2042
|
The
role of transcription factors Tcf in the induced cell pluripotency
(iPS) and during neurogenesis
|
2012-2015
|
O.
Machoň
|
29
|
|
MŠMT
|
LK11214
|
Genetic regulation of the brain and eye embryonic
development
|
2012-2016
|
O.
Machoň
|
29
|
|
MŠMT
|
LH12047
|
Role of alternative mRNA splicing in the evolution of
body plan in vertebrates
|
2012-2015
|
Z.
Kozmik
|
29
|
|
GA ČR
|
GA203/09/0820
|
Structurally inspired synthese of the
selectiv inhibitors nukleotidas, potentially important medicals
|
2009-2013
|
J.
Brynda
|
31
|
|
TA ČR
|
TA 02010797
|
Labelling of recombinant
antibody fragments using microfluidics systems
|
2012-2014
|
J.
Sedláček (spoluřeš.)
|
31
|
|
GA ČR
|
GCP305/10/J052
|
Functional
analysis of endogenous retroviral elements in human genome: possible
association with cancers
|
2010-2012
|
J. Pačes
|
33
|
|
GA ČR
|
GAP305/11/1061
|
Evolution of parasitism:analysis of genomes
and key physiological functions of free-living Mastigamoeba balamuthi
and pathogenic Entamoeba histolytica
|
2011-2015
|
J.
Pačes (spoluřeš.)
|
33
|
|
GA ČR
|
GAP506/11/1317
|
Diversity and evolution of anaerobic
Heterolobosea
|
2011-2014
|
Č.
Vlček (spoluřeš.)
|
33
|
|
GA ČR
|
GAP506/11/1320
|
Establishment of the secondary plastid in
euglenids
|
2011-2015
|
Č.
Vlček (spoluřeš.)
|
33
|
|
GA ČR
|
GAP506/12/1010
|
Sequencing of the oxymonad and trimastix genomes
|
2012-2014
|
V. Pačes (spoluřeš.)
|
33
|
|
GA ČR
|
GAP304/12/1333
|
Cell-to-cell
interactions in malignant melanoma – experimental study
|
2012-2015
|
H. Strnad (spoluřeš.)
|
33
|
|
MZ ČR
|
NT/13488
|
Genomic analysis of tumour-associated fibroblasts in head
and neck cancer: basis for a novel generation of biological antitumour
therapy
|
2012-2015
|
H.
Strnad (spoluřeš.)
|
33
|
|
MZ ČR
|
NT/13112
|
Study of the antitumour effects of statins
|
2012-2015
|
H.
Strnad (spoluřeš.)
|
33
|
|
GA ČR
|
GA203/09/1311
|
Synthetic
probes for recognition of tumor markers: applications for cell directed
apoptosis and targeted photodynamic therapy
|
2009-2012
|
J.
Králová
|
36
|
|
GA ČR
|
GAP305/10/2133
|
The study of satellite cells migration
|
2010-2012
|
P.
Kašpar
|
36
|
|
GA ČR
|
GAP303/11/1291
|
New types of ligands interfering with cancer
cell communication as a new therapeutic strategy
|
2011-2014
|
J.
Králová (spoluřeš.)
|
36
|
|
AV ČR
|
KAN200520801
|
Targeted expression and transport of bioactive molecules
|
2008-2012
|
D. Staněk (+ M. Dvořák)
|
36
|
|
EU -
FP7
|
TRIREME
223575
|
Systems-Level, Multi-Layer Understanding of
Cellular Responses to Ionizing Radiation
|
2009-2012
|
J.
Bartek
|
37
|
|
GA ČR
|
GA204/08/1418
|
The
role of the JAK/STATsignalling pathway in cellular senescence
|
2008-2012
|
Z.
Hodný
|
37
|
|
GA ČR
|
GPP305/10/P420
|
Role of
Wip1 phosphatase in the DNA damage response
|
2010-2012
|
L.
Macůrek
|
37
|
|
GA ČR
|
GAP301/10/1525
|
Mechanisms
of DNA damage checkpoint termination
|
2010-2012
|
J.
Bartek
|
37
|
|
GA ČR
|
GPP305/11/P683
|
Post-translational
modifications of Daxx and their functional relevance in DNA damage
response and cellular senescence
|
2011-2013
|
H.
Hanzlíková
|
37
|
|
GA ČR
|
GAP305/12/2485
|
Structure
and function of proteins involved in DNA damage signaling
|
2012-2015
|
L.
Macůrek
|
37
|
|
GA ČR
|
GA310/08/0878
|
The role of the cells prion protein in
erytroidnic differentiation
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2008-2012
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P.
Bartůněk (spoluřeš.)
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38
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GA ČR
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GAP305/10/0953
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New regulators of megakaryocyte and erythroid
lineage commitment
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2010-2013
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P.
Bartůněk
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38
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OPPK
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CZ-OPENSCREEN
CZ.2.16/3.1.00/24020
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National infrastructure for chemical biology
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2011-
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P.
Bartůněk
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38
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GA ČR
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GAP301/12/1478
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The
role of DISP3 protein in lipid metabolism
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2012-2015
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P.
Bartůněk
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38
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MPO
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TIP
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Development of novel chemical
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2012-
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P.
Bartůněk (+ V. Kořínek)
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38
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TA ČR
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TA02010212
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ReceptorX: Integrated platform for identification and
development of novel drugs
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2012-
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P.
Bartůněk
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38
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MŠMT
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Support for infrastructure operation
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2012-
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P.
Bartůněk
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38
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FP7
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261861
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EU-OPENSCREEN—European
Infrastructure of Open Screening Platforms for Chemical Biology
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2010-2013
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P.
Bartůněk
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38
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GA ČR
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GA204/09/0565
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Role of RECQ5 DNA helicase in maintenance of genomic
stability
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2009-2013
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P.
Janščák
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42
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GA ČR
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GAP305/10/0281
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Role of the Rothmund-Thomson syndrome gene
product in maintenance of genomic stability
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2010-2014
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P.
Janščák
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42
|
|
GA ČR
|
GA204/09/0565
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Role of RECQ5 DNA helicase in maintenance of
genomic stability
|
2009-2013
|
P.
Janščák
|
42
|
|
GA ČR
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GAP302/11/1481
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Serine
proteases of human parasite Schistosoma mansoni and their function in
host-parasite interactions
|
2011-2014
|
J.
Dvořák
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43
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EU FP7
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PIRG05-GA-2009-248642
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Schistosoma
Protease
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2009-2013
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J.
Dvořák
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43
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