Ústav experimentální botaniky AV ČR, v. v. i.
již 50 let poznáváme svět rostlin

Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones

Landa P., Kutil Z., Temml V., Vuorinen A., Malík J., Dvořákova M., Maršík P., Kokoška L., Přibylová M., Schuster D., Vaněk T.
PLANTA MEDICA 78 : 326-333 , 2012
Klíčová slova: inflammation, prostaglandin synthase, structure‑activity relationship, cytotoxicity, free radicals, pharmacophore modeling

In vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1 and -2 catalyzed prostaglandin E2 biosyntheses

Maršík P., Kokoška L., Landa P., Nepovím A., Soudek P., Vaněk T.
PLANTA MEDICA 71 : 739-742 , 2005
Klíčová slova: Nigella sativa - thymol - thymoquinone - cyclooxygenase-1 - cyclooxygenase-2 - anti-inflammatory activity