Publikace za rok 2012

Mikyšková R, Indrová M, Polláková V, Bieblová J, Símová J, Reiniš M. Cyclophosphamide-induced Myeloid-derived Suppressor Cell Population Is Immunosuppressive But Not Identical to Myeloid-derived Suppressor Cells Induced By Growing TC-1 Tumors. Journal of Immunotherapy 2012 35(5):374-84.

Reinišová M, Plachý J, Trejbalová K, Šenigl F, Kučerová D, Geryk J, Svoboda J, Hejnar J. Intronic deletions that disrupt mRNA splicing of the tva receptor gene result in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroup A. Journal of  Virology 2012 86(4):2021-30.

Ballek O, Broučková A, Manning J, Filipp D. A specific type of membrane microdomains is involved in the maintenance and translocation of kinase active Lck to lipid rafts. Immunology Letters 2012 142(1-2):64-74.

Neuwirth A, Dobeš J, Oujezdská J, Ballek O, Benešová M, Sumník Z, Včeláková J, Koloušková S, Obermannová B, Kolář M, Stechová K, Filipp D. Eosinophils from patients with type 1 diabetes mellitus express high level of myeloid alpha-defensins and myeloperoxidase. Cellular Immunology 2012 273(2):158-63.

Stechova K, Halbhuber Z, Hubackova M, Kayserova J, Petruzelkova L, Vcelakova J, Kolouskova S, Ulmannova T, Faresjö M, Neuwirth A, Spisek R, Sediva A, Filipp D, Sumnik Z. Case report: type 1 diabetes in monozygotic quadruplets. European Journal of Human Genetics 2012 20(4):457-62.

Kobets T, Grekov I, Lipoldova M. Leishmaniasis: prevention, parasite detection and treatment. Current Medicinal Chemistry 2012 19(10):1443-74.

Kasparek P, Krenek P, Buryova H, Suchanova S, Beck IM, Sedlacek R. Transgenic mouse model expressing tdTomato under involucrin promoter as a tool for analysis of epidermal differentiation and wound healing. Transgenic Research 2012 21(3):683-9.

Svobodova E, Krulova M, Zajicova A, Pokorna K, Prochazkova J, Trosan P, Holan V. The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population.Stem Cells Development 2012 21(6):901-10.

Prochazkova J, Pokorna K, Holan V IL-12 inhibits the TGF-β-dependent T cell developmental programs and skews the TGF-β-induced differentiation into a Th1-like direction. Immunobiology 2012 217(1):74-82.

Dubský M, Kubinová S, Sirc J, Voska L, Zajíček R, Zajícová A, Lesný P, Jirkovská A, Michálek J, Munzarová M, Holáň V, Syková E. Nanofibers prepared by needleless electrospinning technology as scaffolds for wound healing. Journal of Materials science-materials in Medicine 2012 23(4):931-41.

Homolka D, Jansa P, Forejt J. Genetically enhanced asynapsis of autosomal chromatin promotes transcriptional dysregulation and meiotic failure. Chromosoma 2012 121(1):91-104.

Halova I, Draberova L, Draber P. Mast cell chemotaxis - chemoattractants and signaling pathways.Frontiers in Immunology 2012 3:119.

Draber P, Halova I, Levi-Schaffer F, Draberova L. Transmembrane Adaptor Proteins in the High-Affinity IgE Receptor Signaling. Frontiers in Immunology 2011 2:95.

Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Tamang TD, Khurana MC, Harry EA, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ. Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. Journal of  Biological  Chemistry 2012 287(3):2045-54.

Svojgr K, Kalina T, Kanderova V, Skopcova T, Brdicka T, Zuna J. The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL. Experimental Hematology 2012 40(5):379-85.

Hrdinka M, Otahal P, Horejsi V. The Transmembrane Region Is Responsible for Targeting of Adaptor Protein LAX into "Heavy Rafts". PLoS One 2012 7(5):e36330.

Kolostova K, Taltynov O, Pinterova D, Boubelik M, Raska O, Hozak P, Jirkovska M, Bobek V. Wound healing gene therapy: cartilage regeneration induced by vascular endothelial growth factor plasmid. American Jouranl of Otolaryngology 2012 33(1):68-74.

Dráber P, Sulimenko V, Dráberová E. Cytoskeleton in mast cell signaling. Frontiers in Immunology 2012 3:130.

Vinopal S, Cernohorská M, Sulimenko V, Sulimenko T, Vosecká V, Flemr M, Dráberová E, Dráber P. γ-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis. PLoS One 2012 7(1):e29919.

Katsetos CD, Draber P. Tubulins as therapeutic targets in cancer: from bench to bedside.Current  Pharmaceutical Design 2012 18(19):2778-92.

Hořejší B, Vinopal S, Sládková V, Dráberová E, Sulimenko V, Sulimenko T, Vosecká V, Philimonenko A, Hozák P, Katsetos CD, Dráber P. Nuclear γ-tubulin associates with nucleoli and interacts with tumor suppressor protein C53. Journal of Cellular  Physiology 2012 227(1):367-82

Nejepinska J, Malik R, Filkowski J, Flemr M, Filipowicz W, Svoboda P. dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells. Nucleic Acids Research 2012 40(1):399-413.

Nejepinska J, Flemr M, Svoboda P. Control of the interferon response in RNAi experiments. Methods in Molecular Biology 2012 820:133-61.

Ohrt T, Muetze J, Svoboda P, Schwille P. Intracellular localization and routing of miRNA and RNAi pathway components. Current Topics in Medicinal Chemistry 2012 12(2):79-88.

Solberg N, Machon O, Machonova O, Krauss S. Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sites. Molecular and Cellular Biochemistry 2012 365(1-2):53-63.

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S. A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice. Cancer Research 2012  1;72(11):2822-2832.

Dostál J, Brynda J, Hrušková-Heidingsfeldová O, Pachl P, Pichová I, Rezáčová P. The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir. Journal of Enzyme Inhibition and Medicinal Chemistry 2012 27(1):160-5.

Procházková K, Cermáková K, Pachl P, Sieglová I, Fábry M, Otwinowski Z, Rezáčová P. Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis. Acta Crystallographica section D-Biological Crystallography 2012  68(Pt 2):176-85.

Hrdá Š, Fousek J, Szabová J, Hampl V, Vlček Č. The plastid genome of Eutreptiella provides a window into the process of secondary endosymbiosis of plastid in euglenids. PLoS One 2012 7(3):e33746.

Hroudova M, Vojta P, Strnad H, Krejcik Z, Ridl J, Paces J, Vlcek C, Paces V. Diversity, Phylogeny and Expression Patterns of Pou and Six Homeodomain Transcription Factors in Hydrozoan Jellyfish Craspedacusta sowerbyi. PLoS One 2012 7(4):e36420.

Baldrian P, Kolařík M, Stursová M, Kopecký J, Valášková V, Větrovský T, Zifčáková L, Snajdr J, Rídl J, Vlček C, Voříšková J. Active and total microbial communities in forest soil are largely different and highly stratified during decomposition. ISME Journal 2012 6(2):248-58.

Busek P, Stremenova J, Sromova L, Hilser M, Balaziova E, Kosek D, Trylcova J, Strnad H, Krepela E, Sedo A. Dipeptidyl peptidase-IV inhibits glioma cell growth independent of its enzymatic activity. International Journal of Biochemistry & Cell Biology 2012 44(5):738-47.

Moserova I, Kralova J. Role of ER stress response in photodynamic therapy: ROS generated in different subcellular compartments trigger diverse cell death pathways. PLoS One 2012 7(3):e32972.

Bříza T, Králová J, Cígler P, Kejík Z, Poučková P, Vašek P, Moserová I, Martásek P, Král V. Combination of two chromophores: synthesis and PDT application of porphyrin-pentamethinium conjugate. Bioorganic & Medicinal Chemistry Letters 2012 22(1):82-4.

Moudry P, Lukas C, Macurek L, Hanzlikova H, Hodny Z, Lukas J, Bartek J. Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage. Cell Cycle 2012 11(8):1573-82.

Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J. Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1. Cell Death and Differentiation 2012 19(5):798-807.

Dzijak R, Yildirim S, Kahle M, Novák P, Hnilicová J, Venit T, Hozák P. Specific nuclear localizing sequence directs two myosin isoforms to the cell nucleus in calmodulin-sensitive manner. PLoS One. 2012 7(1):e30529.

Hessler F, Císařová I, Sedlák D, Bartůněk P, Kotora M. Synthesis of ferrocenestrone: the first metallocene based steroid analogue. Chemistry 2012 18(18):5515-8.