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Prague
September 1, 2012


Outstanding publication achievements



2012 June Solberg N, Machon O, Machonova O, Krauss S:
Mouse Tcf3 represses canonical Wnt signaling by either competing for beta-catenin binding or through occupation of DNA-binding sites.
Mol Cell Biochem. 2012 Jun;365(1-2):53-63. Epub 2012 Jan 22. (Pubmed)
2012 May Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J:
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.
Cell Death Differ. 2012 May;19(5):798-807. Epub 2011 Nov 11. (Pubmed)
2012 May Medema RH, Macurek L:
Checkpoint control and cancer.
Oncogene. 2012 May 24;31(21):2601-13. Epub 2011 Oct 3. (Pubmed)
2012 April Moudry P, Lukas C, Macurek L, Hanzlikova H, Hodny Z, Lukas J, Bartek J:
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage.
Cell Cycle. 2012 Apr 15;11(8):1573-82. Epub 2012 Apr 15. (Pubmed)
2012 April Svobodova E, Krulova M, Zajicova A, Pokorna K, Prochazkova J, Trosan P, Holan V:
The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population.
Stem Cells Dev. 2012 Apr 10;21(6):901-10. Epub 2011 Jul 26. (Pubmed)
2012 February Reinisova M, Plachy J, Trejbalova K, Senigl F, Kucerova D, Geryk J, Svoboda J, Hejnar J:
Intronic deletions that disrupt mRNA splicing of the tva receptor gene result in decreased susceptibility to infection by avian sarcoma and leukosis virus subgroup A.
J Virol. 2012 Feb;86(4):2021-30. Epub 2011 Dec 14. (Pubmed)
2012 January Nejepinska J, Malik R, Filkowski J, Flemr M, Filipowicz W, Svoboda P:
dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells.
Nucleic Acids Res. 2012 Jan;40(1):399-413. Epub 2011 Sep 8. (Pubmed)
2011 December Holan V, Chudickova M, Trosan P, Svobodova E, Krulova M, Kubinova S, Sykova E, Sirc J, Michalek J, Juklickova M, Munzarova M, Zajicova A:
Cyclosporine A-loaded and stem cell-seeded electrospun nanofibers for cell-based therapy and local immunosuppression.
J Control Release. 2011 Dec 20;156(3):406-12. Epub 2011 Jul 23. (Pubmed)
2011 November Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T:
SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Mol Cell Biol. 2011 Nov;31(22):4550-62. Epub 2011 Sep 19. (Pubmed)
2011 July Ormsby T, Schlecker E, Ferdin J, Tessarz AS, Angelisova P, Koprulu AD, Borte M, Warnatz K, Schulze I, Ellmeier W, Horejsi V, Cerwenka A:
Btk is a positive regulator in the TREM-1/DAP12 signaling pathway.
Blood. 2011 Jul 28;118(4):936-45. Epub 2011 Jun 9. (Pubmed)
2011 June Stepanek O, Kalina T, Draber P, Skopcova T, Svojgr K, Angelisova P, Horejsi V, Weiss A, Brdicka T:
Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148.
J Biol Chem. 2011 Jun 24;286(25):22101-12. Epub 2011 May 4. (Pubmed)
2011 June Hrdinka M, Draber P, Stepanek O, Ormsby T, Otahal P, Angelisova P, Brdicka T, Paces J, Horejsi V, Drbal K:
PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis.
J Biol Chem. 2011 Jun 3;286(22):19617-29. Epub 2011 Apr 1. (Pubmed)
2011 April Mader P, Brynda J, Gitto R, Agnello S, Pachl P, Supuran CT, Chimirri A, Rezacova P:
Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides.
J Med Chem. 2011 Apr 14;54(7):2522-6. Epub 2011 Mar 11. (Pubmed)
2011 February Novotny I, Blazikova M, Stanek D, Herman P, Malinsky J:
In vivo kinetics of U4/U6.U5 tri-snRNP formation in Cajal bodies.
Mol Biol Cell. 2011 Feb 15;22(4):513-23. Epub 2010 Dec 22. (Pubmed)
2011 February Strnad H, Ridl J, Paces J, Kolar M, Vlcek C, Paces V:
Complete genome sequence of the haloaromatic acid-degrading bacterium Achromobacter xylosoxidans A8.
J Bacteriol. 2011 Feb;193(3):791-2. Epub 2010 Nov 19. (Pubmed)
2011 February Vlcek C, Marande W, Teijeiro S, Lukes J, Burger G:
Systematically fragmented genes in a multipartite mitochondrial genome.
Nucleic Acids Res. 2011 Feb;39(3):979-88. Epub 2010 Oct 8. (Pubmed)
2011 January Hajkova Z, Bugajev V, Draberova E, Vinopal S, Draberova L, Janacek J, Draber P, Draber P:
STIM1-directed reorganization of microtubules in activated mast cells.
J Immunol. 2011 Jan 15;186(2):913-23. Epub 2010 Dec 15. (Pubmed)
2010 October Huranova M, Ivani I, Benda A, Poser I, Brody Y, Hof M, Shav-Tal Y, Neugebauer KM, Stanek D:
The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells.
J Cell Biol. 2010 Oct 4;191(1):75-86. (Pubmed)
2010 August Kanagaraj R, Huehn D, Mackellar A, Menigatti M, Zheng L, Urban V, Shevelev I, Greenleaf AL, Janscak P:
RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription.
Nucleic Acids Res. 2010 Aug 12. (Pubmed)
2010 August Svoboda P, Flemr M:
The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency.
EMBO Rep. 2010 Aug;11(8):590-7. Epub 2010 Jul 23. (Pubmed)
2010 February Ma J, Flemr M, Stein P, Berninger P, Malik R, Zavolan M, Svoboda P, Schultz RM:
MicroRNA activity is suppressed in mouse oocytes.
Curr Biol. 2010 Feb 9;20(3):265-70. Epub 2010 Jan 28. (Pubmed)
2010 January Furugaki K, Pokorna K, Le Pogam C, Aoki M, Reboul M, Bajzik V, Krief P, Janin A, Noguera ME, West R, Charron D, Chomienne C, Pla M, Moins-Teisserenc H, Padua RA:
DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model.
Blood. 2010 Jan 21;115(3):653-6. Epub 2009 Nov 19. (Pubmed)
2010 January Bartek J, Hodny Z:
SUMO boosts the DNA damage response barrier against cancer.
Cancer Cell. 2010 Jan 19;17(1):9-11. (Pubmed)
2009 August Blazkova J, Trejbalova K, Gondois-Rey F, Halfon P, Philibert P, Guiguen A, Verdin E, Olive D, Van Lint C, Hejnar J, Hirsch I:
CpG methylation controls reactivation of HIV from latency.
PLoS Pathog. 2009 Aug;5(8):e1000554. Epub 2009 Aug 21. (Pubmed)
2009 July Stachura DL, Reyes JR, Bartunek P, Paw BH, Zon LI, Traver D:
Zebrafish kidney stromal cell lines support multilineage hematopoiesis.
Blood. 2009 Jul 9;114(2):279-89. Epub 2009 May 11. (Pubmed)
2009 June Pajer P, Karafiat V, Pecenka V, Prukova D, Dudlova J, Plachy J, Kasparova P, Dvorak M:
Industasis, a promotion of tumor formation by nontumorigenic stray cells.
Cancer Res. 2009 Jun 1;69(11):4605-12. (Pubmed)
2009 June Huranova M, Hnilicova J, Fleischer B, Cvackova Z, Stanek D:
A mutation linked to retinitis pigmentosa in HPRP31 causes protein instability and impairs its interactions with spliceosomal snRNPs.
Hum Mol Genet. 2009 Jun 1;18(11):2014-23. Epub 2009 Mar 17. (Pubmed)
2009 May Lukas J, Mazna P, Valenta T, Doubravska L, Pospichalova V, Vojtechova M, Fafilek B, Ivanek R, Plachy J, Novak J, Korinek V:
Dazap2 modulates transcription driven by the Wnt effector TCF-4.
Nucleic Acids Res. 2009 May;37(9):3007-20. Epub 2009 Mar 20. (Pubmed)
2009 May Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori AA, Gerrits B, Shevelev I, Janscak P:
MRE11 complex links RECQ5 helicase to sites of DNA damage.
Nucleic Acids Res. 2009 May;37(8):2645-57. Epub 2009 Mar 6. (Pubmed)
2009 February Wu W, Slastad H, de la Rosa Carrillo D, Frey T, Tjonnfjord G, Boretti E, Aasheim HC, Horejsi V, Lund-Johansen F:
Antibody array analysis with label-based detection and resolution of protein size.
Mol Cell Proteomics. 2009 Feb;8(2):245-57. Epub 2008 Sep 16. (Pubmed)
2009 January Mihola O, Trachtulec Z, Vlcek C, Schimenti JC, Forejt J:
A mouse speciation gene encodes a meiotic histone H3 methyltransferase.
Science. 2009 Jan 16;323(5912):373-5. Epub 2008 Dec 11. (Pubmed)